Conserved Protein Domain Family
Tcp11
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pfam05794: Tcp11 (this model, PSSM-Id:283456 is obsolete and has been replaced by 461743)
T-complex protein 11
This family consists of several eukaryotic T-complex protein 11 (Tcp11) related sequences. Tcp11 is only expressed in fertile adult mammalian testes and is thought to be important in sperm function and fertility. The family also contains the yeast Sok1 protein which is known to suppress cyclic AMP-dependent protein kinase mutants.
Links
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Statistics
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PSSM-Id: 283456
Aligned: 219 rows
Threshold Bit Score: 154.275
Created: 13-Jul-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
O23129        662 FLHDGNLNFPGGStvkdeEDNl---kRRIKETMERAFWDNVMESMkl--------------------------------- 705  thale cress
XP_001645937  218 LRHDIVFDPNLQF-----RPNldgnlGIKKKELADEYWKEVENEIfvyqk------------------------------ 262  Vanderwaltozy...
XP_007399341  252 LRHDLLFDPGLQFr----PTFs-----RRKRDLAESYWIAVVRELdtgctcttldlqgklierrcicgtiplpaekpira 322  Phanerochaete...
ELU39000       77 LRHDLLFDPGLQF-----RPTs----GRKKRDLTDKYWQAVQIEVet--------------------------------- 114  Rhizoctonia s...
XP_003676573  246 LRHDIIFDPSLKFk----QNYdd-kyGSKRKARTDAYWDLIKTELiintrnnnkkn----------------------qi 298  Naumovozyma c...
XP_007403605  552 LRHDIVFDDVLRF-----RPNldgdrGQRKRLVADRYWIAIARELeancrcaafvqrfpdrrpista-pdprqvlgcvcs 625  Melampsora la...
XP_001875779  199 LRHDLLFDPGLQFr----PTCs-----RRKRDLAEKYWAAVMREVetgctcv---------------------------- 241  Laccaria bico...
XP_007329793  179 LRHDILFDSALQFr----PAGh----RRKKENVER-YWDAVAREIesgctcvsydtssrryipt------icvcdrvplp 243  Agaricus bisp...
XP_003686710  246 LRHDIVFDPNLQF-----RPNldgniGVKKRELSQLYWNDLENEI----------------------------------- 285  Tetrapisispor...
KDE04646      448 LRHDIVFDPNLMF-----RPNydgerGERKKRAADRYWYAVSRELvlgcrctafvgserla------------------- 503  Microbotryum ...

O23129        706 --------eK----------PD------------------------------Y------SCISNLMKEVSDELCQMVP-- 729  thale cress
XP_001645937  263 ----rrdvfE----------SR------------------------------R------TRLVPIFDNLRNIILTIVA-- 290  Vanderwaltozy...
XP_007399341  323 yssagnfvtV----------RS------------------------------P------SRLRPLLAELLEVLISIIR-- 354  Phanerochaete...
ELU39000      115 --------gC----------ACtsfdergrrlpcvc---gallsrptssrtlP------SRIPPLVNELCAVLQSVV--- 164  Rhizoctonia s...
XP_003676573  299 hhnhipnihS----------NN------------------------------Q------SLLFLLFDTLKDTILTIIPnw 332  Naumovozyma c...
XP_007403605  626 ggqfneassE----------PNikpgti-------------------pldriP------SRIPPLVEELRNILLSLVV-- 668  Melampsora la...
XP_001875779  242 ---tfdsqgN----------PHrlacvcaqtptspkhpvfsqlsakvytlrmP------SRILTLLCEFLEVLLLVIQ-- 300  Laccaria bico...
XP_007329793  244 tdapltftiP----------PS------------------------------YitvrtpSRVRALLNEFLEVLLHVIQ-- 281  Agaricus bisp...
XP_003686710  286 ---------IiyrndislfnLK------------------------------K------SRLYPLFDNIRKIMMTIVtp- 319  Tetrapisispor...
KDE04646      504 -----cvcqsprsdateisaLW------------------------------P------SRIPNLITELRNIVVSLLP-- 540  Microbotryum ...

O23129        730 --D--------------S-----------------W----------------KV------E----I-------------- 736  thale cress
XP_001645937  291 --P--------------K-----------------D----------------AQ------M----V-------------- 297  Vanderwaltozy...
XP_007399341  355 --Pvvl--------rptGl---------------sL----------------QA------N----Vvssqeqndshvayl 383  Phanerochaete...
ELU39000      165 -----------------------------------------------------------------H-------------- 165  Rhizoctonia s...
XP_003676573  333 kyD--------------Iq---------------sY----------------AV------I----L-------------- 343  Naumovozyma c...
XP_007403605  669 --P--------------RsqalcpnkntdpspsssA----------------HD------V----I-------------- 692  Melampsora la...
XP_001875779  301 --PlskisgiyvnpntfKa---------------qM----------------QEhtaqaaY----I-------------- 329  Laccaria bico...
XP_007329793  282 --P--------------La---------------tLsgpyvksevlqgpveeHA------EqakhI-------------- 310  Agaricus bisp...
XP_003686710  320 ----------------------------------nD----------------YQ------M----V-------------- 325  Tetrapisispor...
KDE04646      541 --V--------------Kps-------------ehS----------------QE------E----V-------------- 551  Microbotryum ...

O23129        737 TETIDLDILSQLLNSGT-LDIDylgKMLEFALATLRKLSAPAND------RENEST------H----------------- 786  thale cress
XP_001645937  298 KNILETSVCVQGIITGS-LDIL---QLADWICKILKGHCAPMRD------TFMKQLyskfeeAt---------------- 351  Vanderwaltozy...
XP_007399341  384 RSILDADLIQQEIEHGV-FDPS---GVFKAIGDIMRCYCAPMRD------QAVNQM------Valaes------------ 435  Phanerochaete...
ELU39000      166 SASADPALIAQELRHGV-FDSR---GVFKNLGSVLKQHCAPMRD------RAVEMM------Va---------------- 213  Rhizoctonia s...
XP_003676573  344 QQYLDPTLLVQEIYAGA-FDAV---DFATCLTNILRQICAPIRDpfletiEETFKM------Ah---------------- 397  Naumovozyma c...
XP_007403605  693 CSTLDPIEISQKLEKGRrIDMP---ALARFLGLVLKGHCAPMRD------NIVDGM------Vslisgeakdftlepdlq 757  Melampsora la...
XP_001875779  330 RSIFDPVLIEQELKRGL-FDPS---GLFRAIGTTLKGHCAPMRD------SAVESM------Vq---------------- 377  Laccaria bico...
XP_007329793  311 RSLFDLDLIEQELKHGV-FDPS---GLFQVIGLTLKNHCAPMRD------HAVDSM------Veaaka------------ 362  Agaricus bisp...
XP_003686710  326 KDVLNPEMNVQNLIRDT-LDVN---NLSSWIYDILKKYCAPMRD------SLVEKL------Nta--------------- 374  Tetrapisispor...
KDE04646      552 MEMLDPAFIYQQLTRGL-LDVG---KLADYLGVTLKMHCAPMRD------HMIDNM------Ari--------------- 600  Microbotryum ...

O23129        787 --------RdllkelhrlceaedesgnfrAVAIVKGIRFILEQIQELKREIGIGR---IAIMKPFLQGPAgFDYLTKAFE 855  thale cress
XP_001645937  352 -------tEd------------------sLSKFVGAIRFLFHVLEIMKLDVANHQ---IRLLRPALVSNT-VEFERQYYQ 402  Vanderwaltozy...
XP_007399341  436 ---cspggTg------------------tKVDAVRAIRLCFEILELMKLDVANHQ---LQTLRPYLVRSA-AQFELKMFQ 490  Phanerochaete...
ELU39000      214 -------vAs------------------rPGGGVRAVRMCFEILELMKL-VSCHLpldLAPLRPYLFETA-VDFELKTFQ 266  Rhizoctonia s...
XP_003676573  398 -------vSn------------------sVSKFIDALKLTFHTLELMKLDIANHE---LKLLRPTLLENT-IEFEKQYFT 448  Naumovozyma c...
XP_007403605  758 nsahdslqKs------------------sYAGLAGGLRMSFELLELMKLDIANHQ---LRTLRPVLLETA-LEFEIRHFR 815  Melampsora la...
XP_001875779  378 -------aAhtcvk-----------ngnsGTNAVKALRMCMEILELMKLDIANHQ---LQTLRPFLIRTS-GQYELKTLK 435  Laccaria bico...
XP_007329793  363 ---capggSa------------------tIRDAVKVVRNCSEILELMKLDIANHQ---MQTLRPFLVYSS-GAFERKMLR 417  Agaricus bisp...
XP_003686710  375 -------fEkaie-------------lksLHEFIGCIALFLEIMELMRLDMANHQ---IRLIRPALISNS-IEFERQYNQ 430  Tetrapisispor...
KDE04646      601 -------cKg------------------dDASVALGLRHCFEILEMMKLDIANHQ---LRSLRPYLVRTA-VEFERNHQQ 651  Microbotryum ...

O23129        856 KRYGPPtqayesLPVTRRWISTLLSSKE-EWEehnntlsalnvverssmgislktggsflspvnttskstvMD------- 927  thale cress
XP_001645937  403 TILSTPnn---kLIPSFDWFKIKYNEEVtKGKli------------------------------------aGQ------- 436  Vanderwaltozy...
XP_007399341  491 ENRQKGpl---pLEATRQWLQTAFDDLAaQTTdp------------------------------------rSS------- 524  Phanerochaete...
ELU39000      267 ERHERGll---tLSTTQEWLRKAASTFSsPPPt----------------------------------------------- 296  Rhizoctonia s...
XP_003676573  449 VLFENEdp---hLTSSLAWFQDAILKLDpPVKi----------------------------------------------- 478  Naumovozyma c...
XP_007403605  816 DQLIKRp----sIDRTKRWYSEAVARVqg-----------------------------------------sSG------- 843  Melampsora la...
XP_001875779  436 NRHGs-------IRVTQEWLHAAHTAMLtRNQpi------------------------------------sHPlyppeyl 472  Laccaria bico...
XP_007329793  418 SRRSIDp----sLPLTKEWLRFAHTTFs-SQEep------------------------------------iKY------- 449  Agaricus bisp...
XP_003686710  431 TILSKPnn---iYVSSFHWFKKT---YDeevsn----------------------------------------------- 457  Tetrapisispor...
KDE04646      652 IRLSSEe-----SERVRQWLIKTSPEDGsAIRdr---------------------------------------------- 680  Microbotryum ...

O23129        928 -TAGQLSeckg-----ervDLAV------RLGLLK-----------L------------------VN------------- 953  thale cress
XP_001645937  437 -TTPQLL------------YRFN------IRNILE-----------L------------------AS------------- 455  Vanderwaltozy...
XP_007399341  525 -SNLSASys--------ryPRFLqiqlsvVRAVIN-----------L------------------IF------------- 553  Phanerochaete...
ELU39000      297 -------------------MHLL------SHALTS-----------LifsppttvstpppptttpLS------------- 327  Rhizoctonia s...
XP_003676573  479 -TFGNIRak--------fiYRAF------IRCTIN-----------L------------------LS------------- 501  Naumovozyma c...
XP_007403605  844 -LSNLLPae--------qiSRAV------QDGLLDfpfssasppsdS------------------AL------------- 877  Melampsora la...
XP_001875779  473 kPSALSGnq--------qlYLAT------LKGIVD-----------L------------------VF------------- 496  Laccaria bico...
XP_007329793  450 -PSQPQGlrytslgkkhqlYISV------VRSIVD-----------M------------------VFdppsssspslvtt 493  Agaricus bisp...
XP_003686710  458 -gnlivGqtlp-----rqiYRLV------IKDILN-----------L------------------TS------------- 483  Tetrapisispor...
KDE04646      681 ------------------vSRSV------LQGVLG-----------L------------------AF------------- 694  Microbotryum ...

O23129        954 -----Qv----------------------aGL---TPEV-LPETFQLNLFRVRDIQAEIQNIIVVTTSLLIWrQMLA--- 999  thale cress
XP_001645937  456 -----Ch-----------------------N----MVQS-YPVALGFDRSRLILLRTNIRQIVCLMICRLLF-KQLI--- 498  Vanderwaltozy...
XP_007399341  554 -----Dsaslpsppsspl-pssiassplvsSP---TRQG-YPETLYLDHIRLTTLRNDAADFTTLYMLMMLY-RQLVhsg 622  Phanerochaete...
ELU39000      328 -----Qr-----------------------LPhiaPPPG-YPETLYLDHARLAGLTADAADLGVLYAVLMLF-RQLVys- 376  Rhizoctonia s...
XP_003676573  502 -----Cc-----------------------QI----VEK-FPGALYFDHSRLMSLRVDVRHLICHYICKLLY-KLMI--- 544  Naumovozyma c...
XP_007403605  878 -----Tp-----------------------SP---SPSF-VPETFSMDTIRLQTLHSDLTDLTIAYLIIMLF-KQLV--- 921  Melampsora la...
XP_001875779  497 -----DsplsnstsatptntplcspitaptQP---QLTS-FPETLYLDTSRIQLLSSDAIDATALYMFLLLY-RQLI--- 563  Laccaria bico...
XP_007329793  494 tlpspPs-----------------------DL---PFPS-FPETLYLDQARIQTYTSEIADLVALWMFLLLY-RQLI--- 542  Agaricus bisp...
XP_003686710  484 -----Csn---------------------------mVDE-FPIILSTDKALLLSLRSKIRQIVCLMICKLLF-DQLV--- 526  Tetrapisispor...
KDE04646      695 -----Ssv---------------------tPS---PPQPtLPFTFQLDAFRLKMHRNEATDLTLLYMLMMLF-QELV--- 741  Microbotryum ...

O23129       1000 ----KSese----------------teSMAKKLLELldgke----------------------------------gaglt 1025 thale cress
XP_001645937  499 ----SQhknidtlakn--yittkytdeRLKSEIMSLiteehg---------------------------------nfkwt 539  Vanderwaltozy...
XP_007399341  623 stpaGPkiavs-----------sddlaALKKEIWEIgparlgycftcrpa----------------sgiadseselaawr 675  Phanerochaete...
ELU39000      377 ---tGSkvsle-----------dsvvdRVKREIWEVgpvrlglcfsgr--------------------kpgddeewekwr 422  Rhizoctonia s...
XP_003676573  545 ----SKdenlndklke--nllsknnmdKLMNELEIIitdqyg---------------------------------hskwt 585  Naumovozyma c...
XP_007403605  922 ----GHsklke------------gdveTLKSELWVLmsepglkvkgkpg-------------------iglkkieskswr 966  Melampsora la...
XP_001875779  564 ----FSestdaaasdp--pkvndsdiaRLKREIRDIgttrlgccftrqald--------------hmeskvgnkeaerwr 623  Laccaria bico...
XP_007329793  543 ----SSfghrkyqk-----erinefasILKREIRAIgprslhtcfl-------------------------ecsnssgsn 588  Agaricus bisp...
XP_003686710  527 ----MHheavridnklktfikssysneEMIADIIAIikdesg---------------------------------nfkwt 569  Tetrapisispor...
KDE04646      742 ----PSsrsca------------kellELRQCIAGVistanaaisqnaptvttastesrfkaatmqgtakfdcdewrhel 805  Microbotryum ...

O23129       1026 EI-------------IETTmsEed-----------------------------------geK------------------ 1039 thale cress
XP_001645937  540 KNtm---------siALQLckVieelyldylretkl-----------pqygipqtvaldekQ------------------ 581  Vanderwaltozy...
XP_007399341  676 KDmd---------dvVLQLttKaceararsrsstaspspa---ssiapvqrpipssapdshL------------------ 725  Phanerochaete...
ELU39000      423 AGmr---------dvVLQVavRaeqvrsgvafds----------------skppttlpdakT------------------ 459  Rhizoctonia s...
XP_003676573  586 KNts---------wiATHIckTirdqqtvnpplsss-----------ssssssssdclreeD------------------ 627  Naumovozyma c...
XP_007403605  967 AGfe---------svLLHIgsRieslrngeggsk----------------gemraavpgkeL------------------ 1003 Melampsora la...
XP_001875779  624 IVkq---------diVLQVakRan-----------------------------------daRnrtalstsapsspvgdap 659  Laccaria bico...
XP_007329793  589 QNpttdklksaldnvVLQIarRassiqrgqelpeig------------alpsmtddipskfT------------------ 638  Agaricus bisp...
XP_003686710  570 RN-------------TSAVslHlyykiqqlinrynieqnepgenrqesktstpafvnlaeeN------------------ 618  Tetrapisispor...
KDE04646      806 RH-------------VGQImaGfatklattavry----------------apainsntvhdM------------------ 838  Microbotryum ...

O23129       1040 ----KKMMRGLLGKSLGEGNT----VYERVTSCIYKAARG------AL-------------------LA----------- 1075 thale cress
XP_001645937  582 ----IEFAKAWLSKQIQPNSpvyilLETRVFKSLEDIIYS------RSgctvegnvkqdfltvysknAS----------- 640  Vanderwaltozy...
XP_007399341  726 ----LKLATSWTDSHLRSDSPlgalMKKRVKEAVEDLAIS------IVlps--------------laSS----------- 770  Phanerochaete...
ELU39000      460 ----LGLLESWTDNNLKPDAplaklFKGRLTKAVEQVVNN------STrkkesde------------------------- 504  Rhizoctonia s...
XP_003676573  628 ----VQFANSWLTTQFDPASKiytiLEKKLFDSLELEIFK------RS-------------------QCddygsivddfl 678  Naumovozyma c...
XP_007403605 1004 ----MKVIQNWMDQHLRLQSTlfaitiRRLRETVEFVINE------ESe------------------AA----------- 1044 Melampsora la...
XP_001875779  660 dervLNVAQCWAELNMQEGSSlstmLHSRLRDVVFTAVVAlaypsrDS-------------------AT----------- 709  Laccaria bico...
XP_007329793  639 ----VSVARKWVDANMKLHSSlrklLHGRLKKVVFERVLA------DV-------------------YP----------- 678  Agaricus bisp...
XP_003686710  619 ----IAFAKQWLAKQIQSNTPvyqlLEKRVYKIIENVIYN------IS-------------------DCt---------- 659  Tetrapisispor...
KDE04646      839 ----PTLVESYIQTHVRSHSKvfilLRSRLQGAVTAVVQD------EL-------------------ALg---------- 879  Microbotryum ...

O23129       1076 -------GNgengkrmv--------------------------------------------------------------- 1085 thale cress
XP_001645937  641 -------YKnkmtsst---------------------------------------------------------------- 649  Vanderwaltozy...
XP_007399341  771 -------TKpdapsvq---------------------------------------------------------------- 779  Phanerochaete...
ELU39000          --------------------------------------------------------------------------------      Rhizoctonia s...
XP_003676573  679 ysfneepEDgkitkii---------------------------------------------------------------- 694  Naumovozyma c...
XP_007403605 1045 -------ERnpssniptclrtgrslnsisthhqdk--------------------------------------------- 1072 Melampsora la...
XP_001875779  710 -------GKtmltadflsslsp---------------------------------------------------------- 724  Laccaria bico...
XP_007329793  679 -------ARseaalekmmgkeiegwgevllpskdc--------------------------------------------- 706  Agaricus bisp...
XP_003686710  660 ------lGGeinqsymkvfnknekkidlktlislsk-------------------------------------------- 689  Tetrapisispor...
KDE04646      880 ------tEMkgapwwmrptvsplasqtsitldprrsrrtgctgersmdivpaeanmkakavsatrrgtkrasldeqecre 953  Microbotryum ...

O23129       1086 ---------------------etemkkvgGGGGLKE-------------------------------RVLETARALGVVA 1113 thale cress
XP_001645937  650 ----------------------nekpkpdSELESEDtdstndnnvtndndndngsnrqqqiiplslsNFENTISLSYVLS 707  Vanderwaltozy...
XP_007399341  780 ----------------------eaarvasGLEPLLP-------------------------------EVRHLAQKLSKLV 806  Phanerochaete...
ELU39000      505 ----------------------ekevvaaGLEPLMP-------------------------------EIRHLGERIGKLA 531  Rhizoctonia s...
XP_003676573  695 ----------------------mdprnviFETFEKK-------------------------------QYEKVLAYVQAIA 721  Naumovozyma c...
XP_007403605 1073 ---qeeieeanrlkhkkgsdggveiwkksGLVELEY-------------------------------EIRVVGNRLKKLL 1118 Melampsora la...
XP_001875779  725 -----------------ksaegasawmmsGMEPLAN-------------------------------EIRSLSEKISRLA 756  Laccaria bico...
XP_007329793  707 ---lgialpksaipfsdnkapaqedgmgnGLEMLSD-------------------------------EVQSLVEKISLLV 752  Agaricus bisp...
XP_003686710  690 ---sshynnnannedennntlfllsdeqkFLPISLK-------------------------------HFENEILLATTLI 735  Tetrapisispor...
KDE04646      954 krarysapntdkidlplhspdlntvlvrnGLTPLAD-------------------------------QIRSLGERLAKLT 1002 Microbotryum ...

O23129       1114 CVSVRVHGPWLTQ 1126 thale cress
XP_001645937  708 NFHWSVFGFHYIK 720  Vanderwaltozyma polyspora DSM 70294
XP_007399341  807 SIHLNVYGTLYTQ 819  Phanerochaete carnosa HHB-10118-sp
ELU39000      532 SFHGRVYRGLYEA 544  Rhizoctonia solani AG-1 IA
XP_003676573  722 NFQWSVFGTQYfl 734  Naumovozyma castellii CBS 4309
XP_007403605 1119 KYHLRGYGGLYAH 1131 Melampsora larici-populina 98AG31
XP_001875779  757 LIHLNAYLPLYEK 769  Laccaria bicolor S238N-H82
XP_007329793  753 VVHFNAYLPVYEK 765  Agaricus bisporus var. burnettii JB137-S8
XP_003686710  736 NFHWSVVGYHYVQ 748  Tetrapisispora phaffii CBS 4417
KDE04646     1003 SFHLAVNSDFYQA 1015 Microbotryum violaceum p1A1 Lamole
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