Conserved Protein Domain Family
Na_trans_assoc

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pfam06512: Na_trans_assoc (this model, PSSM-Id:284034 is obsolete and has been replaced by 399489)
Sodium ion transport-associated
Members of this family contain a region found exclusively in eukaryotic sodium channels or their subunits, many of which are voltage-gated. Members very often also contain between one and four copies of pfam00520 and, less often, one copy of pfam00612.
Statistics
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PSSM-Id: 284034
View PSSM: pfam06512
Aligned: 68 rows
Threshold Bit Score: 96.2056
Threshold Setting Gi: 241153636
Created: 14-Jul-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P15390        810 DGEMNNLQIAIGRIKWGIGFAKTFLLG---LLRGKILSP--KEiilslgepggagenaeestpEDEKK--EPPPEDkEL- 881  Norway rat
BAP46858     1031 DNETNKIAEAFNRISRFSNWIKSNIANalkFVKNKLTSQ--IA--------------------SVQPA--EHGENElEL- 1085 yellow fever ...
XP_012347671  717 DNDTNKIAEAIDRIARFVKWIKRNVL----YLAKMMRAKltNQ--------------------ISDQA--PGEGPSnSW- 769  little honeybee
EFA11577     1033 DNDTNKIAEAFDRIGRFIRWIKGNVLH---I------------------------------------------AKLvRF- 1066 red flour beetle
XP_011266384 1025 DNDTNKIAEAIDRIARFINWIKRNILN----IAKLMRAKftNQ--------------------ISDQA--PGEGPSnSW- 1077 Florida carpe...
NP_001138205 1035 DNDTNKIAEAFNRIGRFKSWVKRNIAD---CF--KLIRN--KL--------------------TNQISdqPSEHGDnEL- 1086 fruit fly
ABP96886      480 DQDTNKIAEAFNRISRFIDWIKRNVAD---FL------------------------------------------KLlKNk 514  domestic silk...
XP_008204157 1021 DNDTNKITEAIDRISRFIAWTKRNILN---LL------------------------------------------KMlRAk 1055 jewel wasp
XP_002427248  967 DNDTNKIAEAFNRISRFNAWVKRSILN---FL------------------------------------------KMlRAk 1001 human body louse
EFX81393     1003 DNDTNKLTEAFNRISRFKRWVRRSFSN---GF------------------------------------------RMiRSk 1037 common water ...
P15390        882 K-DNH--ILNHVGLTD-GPRSSIE------------------LDHL--N-------------F-----I----N------ 909  Norway rat
BAP46858     1086 T-PDD--ILADGLLKK-G-VKEHNqle------------vaiGDGM--E-------------F-----T----I------ 1118 yellow fever ...
XP_012347671  770 K-EDG--I-DRDGDLD-LADGELDayrdkksakelnqlevaiGDGM--E-------------F-----T----Ihgdlkn 820  little honeybee
EFA11577     1067 KlTNQ--ISDQPSDVRcDGGLDIS------------------GDEIlaD-------------G-----IikksP------ 1102 red flour beetle
XP_011266384 1078 K-EDG--I-DRDGDLD-LADGELDayrdkksakelnqlevaiGEGM--E-------------F-----T----I------ 1122 Florida carpe...
NP_001138205 1087 E-LGHdeILADGLIKK-GIKEQTQlev-------------aiGDGM--E-------------FtihgdM----K------ 1126 fruit fly
ABP96886      515 L-TNQ--IAIH--APer------------------------vDNEL--Elgtdld-davlykD-----K----K------ 547  domestic silk...
XP_008204157 1056 F-TNQ--ISDQ--APgegpsnswked-----gidrdmnmdlaEGEL--Dayr-------dkkS-----V----K------ 1101 jewel wasp
XP_002427248 1002 I-SNQ--IGDHtgLPdgr----------------------drDTDL--ElgdeilvdgmvfrD-----K----K------ 1039 human body louse
EFX81393     1038 L-TNQ--ISDQrapgelplfqigpfyfqcg--------------------------------------------lfvfnf 1070 common water ...
P15390        910 ---------N--P---------YL-------------------T--------------IQVPIA---------------- 920  Norway rat
BAP46858     1119 ---------H--G---------DLknkgkknkqlmnnskvignS--------------ISN------------------- 1145 yellow fever ...
XP_012347671  821 klkkgklcmN--N---------SK-------------------V--------------IANSIN---------------- 840  little honeybee
EFA11577     1103 ---------K--D---------RL-------------------E--------------VT--IG---------------- 1111 red flour beetle
XP_011266384 1123 ---------H--G---------DL-------------------KnklknklcmnntkvIANSIN---------------- 1147 Florida carpe...
NP_001138205 1127 ---------N--NkpkkskylnNA-------------------Tm-------------IGNSIN---------------- 1147 fruit fly
ABP96886      548 ---------Lk-D---------QV-------------------E--------------VA--IGdgmeftipgdnkykk- 572  domestic silk...
XP_008204157 1102 ---------ElnN---------QF-------------------E--------------VA--IGdgmeftihgdlknkmr 1128 jewel wasp
XP_002427248 1040 ---------NskD---------QL-------------------E--------------VA--IGdgmeftihgdfkeklr 1066 human body louse
EFX81393     1071 rasgmpaalhirR---------HI-------------------E--------------IVvkIAasclflicdesmsklk 1108 common water ...
P15390        921 --------------------SEE-----------------------SDLEMp-----tE--------E---------ETD 935  Norway rat
BAP46858     1146 --------------------HQD-----------------------NKLEH-------ElnhrgmslQ---------DDD 1166 yellow fever ...
XP_012347671  841 --------------------HRD-----------------------YRLDNdy---inQ--------N---------EDD 857  little honeybee
EFA11577     1112 --------------------TGMdltvhgdpkrgknninksktignSILEHgmy--igH--------L---------DED 1152 red flour beetle
XP_011266384 1148 --------------------HHD-----------------------YRLDNdy---inQ--------N---------EDD 1164 Florida carpe...
NP_001138205 1148 --------------------HQD-----------------------NRLEH-------ElnhrglslQ---------DDD 1168 fruit fly
ABP96886      573 ------gkilmnniyrithyHRD-----------------------NRLD--------C--------ElnhhgypiqDDD 607  domestic silk...
XP_008204157 1129 t---slclnntkalvnsinhHRD-----------------------FRLD--------H--------Dymn----hnEDD 1162 jewel wasp
XP_002427248 1067 rskmalnnknnvignsyaglNSD-----------------------NRFE--------S--------Dyit----hnEED 1103 human body louse
EFX81393     1109 ----nkkganntsavcpnstKKRp----------------------DELVldidcrknP--------K---------DDD 1145 common water ...
P15390        936 AFSEP------------------------EDIKKPLQP-----LY--------DGNSSVC-------------------S 959  Norway rat
BAP46858     1167 TASIKsygshk-------------nrpfkDESHKGSAEtmegeEK--------RDVSKED-------------------L 1206 yellow fever ...
XP_012347671  858 TISNKsygshk-------------nrafkDESHKGSMDsldgeEK--------KDASKED-------------------L 897  little honeybee
EFA11577     1153 EISNKsy---------------------gSHKNRFKEEshkgsVDmlddheekRDASKEE-------------------L 1192 red flour beetle
XP_011266384 1165 TISNKsygshk-------------nrafkDESHKGSMDslngeEK--------KDASKED-------------------L 1204 Florida carpe...
NP_001138205 1169 TASINsy---------------------gSHKNRPFKDeshkgSA--------ETMEGEEkrdaskedlgldeeldeegE 1219 fruit fly
ABP96886      608 TISQKsygshkirsfkdeshkgsadtidgEEKKD---------------------ASKEE-------------------L 647  domestic silk...
XP_008204157 1163 TISNKsygshknrsfkdeshkgsldsldgEEKKD---------------------ASKED-------------------L 1202 jewel wasp
XP_002427248 1104 TYSNIsygshrkriykdeshkgsidtfeeDEKGD---------------------MSKEE-------------------- 1142 human body louse
EFX81393     1146 TISYQsygshchritrdeshkgslrvdyyDEKRN---------------------ASKE--------------------- 1183 common water ...
P15390        960 T-----------------ADYKPP----------EEDPEEQAEENPEGEQ---------------------PEECFTEAC 991  Norway rat
BAP46858     1207 G-----------------ID---------------EELDDECDGEEGPLDgeliihad-----edeviedsPADCCPDNC 1249 yellow fever ...
XP_012347671  898 E-----------------QEEDLGeegeegegviGDAIIQAEEDPIESDY---------------------PADCCPENC 939  little honeybee
EFA11577     1193 G-----------------I----G----------EEETEDDRFDLEKPLTdivivgna-----ddiiiddyAADCFPDSC 1236 red flour beetle
XP_011266384 1205 EqegedledegeegeevdIDIIQA----------EEDPIQ-----DNY-----------------------PSDCCPENC 1246 Florida carpe...
NP_001138205 1220 C-----------------EEGPLD----------GDII--IHAHDEDILDe-------------------yPADCCPDSY 1251 fruit fly
ABP96886      648 G-----------------LE---------------EELIEEDE--EGKLDgtlgktdikv-gadedvvddtPADCCPEQC 692  domestic silk...
XP_008204157 1203 E-----------------DDldd----------egEDEDEEEEEVEE-IPcriikqde------eldgensPSDCCPDNC 1248 jewel wasp
XP_002427248 1143 -----------------------------------DEEMDEEEEGESIPEidviidanm----edvmlqdyPSDCCPDHC 1183 human body louse
EFX81393     1184 -------------------Dldg----------fpEEARPAEVEGEDDGLaaeaavvkiahrvdsdedpqyPDACFPDHW 1234 common water ...
P15390        992 VKRCPCLYVDISQGRGKMWWTLRRACF 1018 Norway rat
BAP46858     1250 YKKFPVLAGDDDAPFWQGWANLRLKTF 1276 yellow fever mosquito
XP_012347671  940 YKKFPFLAGDDDAPFWQGWANLRLKTF 966  little honeybee
EFA11577     1237 YKKFPFLAGDEDSPFWQGWGNLRSKTY 1263 red flour beetle
XP_011266384 1247 YKKFPFLAGDDDAPFWQGWANLRLKTF 1273 Florida carpenter ant
NP_001138205 1252 YKKFPILAGDDDSPFWQGWGNLRLKTF 1278 fruit fly
ABP96886      693 YQKFPFLAGDDDSPFWQGWGTLRLKTF 719  domestic silkworm
XP_008204157 1249 YQRFPFLAGDDDAPFWQGWATLRLKTF 1275 jewel wasp
XP_002427248 1184 YKRFPFLAGDDDAPFWQGWSNLRLKTF 1210 human body louse
EFX81393     1235 YEKIPIIKGNDDSPFWQGWAMLRLKTF 1261 common water flea
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