Conserved Protein Domain Family
SHR-BD
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pfam06650: SHR-BD (this model, PSSM-Id:284143 is obsolete and has been replaced by 461974)
SHR-binding domain of vacuolar-sorting associated protein 13
SHR-BD is a family of eukaryotic proteins found on vacuolar-sorting associated proteins towards the C-terminus. In plants, the domain is found to be the region which interacts with SHR or the SHORT-ROOT transcription factor, a regulator of root-growth and asymmetric cell division that separates ground tissue into endodermis and cortex. The plant protein containing the SHR-BD is named SHRUBBY or SHBY, UniProtKB:Q9FT44.
Links
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Statistics
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PSSM-Id: 284143
Aligned: 28 rows
Threshold Bit Score: 209.858
Created: 25-Jun-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q54LB8   2404 RTLSFYCQYWLVNNSLLPIEVKLSDNqVLLVPPnLPD---Q---LPRPPVLYSNNTiRariPLQAEQPMNKS-------- 2469 Dictyostelium dis...
O42926   2084 SKVMIYPPYVIFNHTDLSIQVTSSSP-NSIRYT-IPSg--Sy-sNDIKPYFYSFDE-S---GRKNRAMISIDng------ 2148 Schizosaccharomyc...
P87319   2142 YHIEIFSPYIIINKSGSFLFVGPKNDyNRISFS-SASlssGe-dGKVVPCMFSYSH-N---YGSRRCRLRADns------ 2209 Schizosaccharomyc...
Q9VU08   2809 MELYISAPVWIINKTGLPLIYKQEGTsHTAAGQ-FEe---HetaRQVAPLMFSFSD-Q---EGSPALVLRLGkayg--sn 2878 fruit fly
Q171S2   2807 IQISISAPYWLINKTGIPLVFRQDDLdCESAGQ-FSEn--Eq-aRMISPFMFAFSD-P---SCSGCLTMRLGkrfg--qs 2876 yellow fever mosq...
Q7Q1I0   2826 VQISIGAPYWLVNRTGLPLVFRQDDLdTECAGQ-FSEn--Ee-aRMITPFMFAFSD-P---GCSGSVTMRLGrrfg--gs 2895 Anopheles gambiae...
Q555C6   5082 HIASIYCTNAIQNHTMIPFLLRPSNMkLVNALT-LE--------TNGDPLMISHDKfY---CYHPSApk----------- 5138 Dictyostelium dis...
A0C9X9   2352 REYVIHCSGYIINKSGIPLKYFT--NnNKNDLT-PLg------gMESINTGDPLNRqIvllGTESGNILSLSht------ 2416 Paramecium tetrau...
Q22YP6   2859 rQFYIYCKGYLINESPYKLNVFTQDNkKKEERK-LVg------gQRQIYPDEALNTnIillGQNTGDLMSLSdak----f 2927 Tetrahymena therm...
BAD32230  805 LKIFISAPYWLINKTGLPLIFRQDNAkTDAAGQ-FEE---HelaRSLSPLLFCYAD-K---EQPNLCTMRIGrgihpegm 876  house mouse

Q54LB8   2470 --FCE-----KFPISAVGNPNTIFLTNPTRtYe------LSYKVDFCPNERFRl--SKTVTFVPKNVICNDLPFPILVAQ 2534 Dictyostelium dis...
O42926   2149 tsWSA-----DIGFDTLGSSSQVEVRKTNE-Sdv---clLGMSISESSGKFCL---TKSVTFTPRFVFKNHLDCTVSLRE 2216 Schizosaccharomyc...
P87319   2210 -nWSE-----PVSFDAIGSVFEVELPSKED-Hnkv--yrLGIFVETGPDGYSK---TNIVTITSRFIVRNKTRWSLVIAE 2277 Schizosaccharomyc...
Q9VU08   2879 nmWCK-----SFSTHKDLADRDLRAENTKGsYa------IGISVRRGRGLYAC---TTFVTLSPRFHLHNRSGYKLEFMQ 2944 fruit fly
Q171S2   2877 tiYCQ-----PFKLDQGIKHRQLI----GGsEsf----iIGIEVQRARGRYNQ---TSIVTFSPQYQLYNRSSYKLQVLQ 2940 yellow fever mosq...
Q7Q1I0   2896 pnWCQ-----PFKLEQGTQHRQLR----GPsEtf----iIGIEVRRARGKYGQ---TSIVTFSPRYQLYNRSSYTLQVLQ 2959 Anopheles gambiae...
Q555C6   5139 -iPSK-----EFDI-ILGKEDIIEIQFDAS-Kdqm-rfqFKAIVSTGFNIFFR---TRIVDIYPRFVLVNKLPISLSYTQ 5206 Dictyostelium dis...
A0C9X9   2417 -sTNQkisqfPIQISTIGEPEIDVIISNEEdTnqllqtfLGAKLELGRCNKKYtlfNKIITLEPRFIIINNCNQDIVIAS 2495 Paramecium tetrau...
Q22YP6   2928 dqVSK-----QASIGGVGNTQIDIQTINEQgDtvf--qtMGINVSLKNVDYEQklfSKVITISPRFIIVNKTGYALELKQ 3000 Tetrahymena therm...
BAD32230  877 pgWCQ-----GFSLDGGSGVRALKVIQQGN-Rpgl-iynIGIDVKKGRGRYID---TCMVIFAPRYLLDNKSSHKLAFAQ 946  house mouse

Q54LB8   2535 CVStid---gidKmalnfsgSGlssssgsngkgvsnpvrllgElRLDPGEYKPFHWEENVENKKIS----IRPITNe--k 2605 Dictyostelium dis...
O42926   2217 FGS---------S-------KV--------------------L-HLPSNELIPMMYFSNPQEIALL----LSLPSS---- 2251 Schizosaccharomyc...
P87319   2278 PYN---------D-------FI--------------------A-EIAPEGEEFLTYLRKHSHPMLK----L--------- 2307 Schizosaccharomyc...
Q9VU08   2945 LCDivnydrpdpR-------KI--------------------I-SAPVDCNFAFHWPNWDQEQIIC----VRIPEIe--- 2989 fruit fly
Q171S2   2941 KCFt--------S-------TVhdaia-----------ksnsI-EAVPGCHIAYHWPRLDKVQELC----VRLPEIp--- 2986 yellow fever mosq...
Q7Q1I0   2960 KCLvd------tT-------TVydptmvarssstsssssaacI-EAVPGCHIPFHWPRLEREHELC----VRLPEVp--- 3018 Anopheles gambiae...
Q555C6   5207 VNKdla---imaK-------DS--------------------Q-LLGPESSIPFHWFNGKEEQQLS----ISIGQGtsds 5251 Dictyostelium dis...
A0C9X9   2496 DE----------D-------LF--------------------SqSVPSNQRIIFQSHYNSKTKIRNpcqfISMNLSn--n 2536 Paramecium tetrau...
Q22YP6   3001 NSV---------N-------KI--------------------I-AINKDSRIPLYWFDDNKDRFLN----IRLVEEe--k 3037 Tetrahymena therm...
BAD32230  947 REFargqgtanpN-------GY--------------------I-STLPGSSVVFHWPRNDYDQLLC----VRLMDVp--- 991  house mouse

Q54LB8   2606 NPQew-rWSGGFFVDSI-SDYVVKSRNteRpdhDSL--LFHVNIKEKQGTHFIRIPLSSKEsPPYIIQND-TQFkISFFQ 2680 Dictyostelium dis...
O42926   2252 NNH----WTSPFLAQNV-GIVHLKAFEfdDddnNMSttLLRLCVTLEDATFFVTITKEDKA-WPFRLKNCtSRE-ICYEQ 2324 Schizosaccharomyc...
P87319   2308 SSSdcylWSSSFYIEEI-GSTHVRLMT------SEGekLLRLEIVIKNATIFISIFEETGD-WPYYIKNEsGVL-LKFWQ 2378 Schizosaccharomyc...
Q9VU08   2990 CCC----WSKGIPIKDV-QSLYINVRN--E---WGEmfFLRLEIISKDATFILLFTDARTLpPPIRIDNCsEVV-INFSQ 3058 fruit fly
Q171S2   2987 ECL----WSAGIPICET-QSLYINIRT--V---NGAmhFLRLETIVQGATTFMIFSDAQSLpPPIRLDNYsEVP-IVFHQ 3055 yellow fever mosq...
Q7Q1I0   3019 ECL----WSGGIPITSTgLSLYINIRN--M---NGAmhFLRLETILHGATYFMIFSDAQALpPPIRLDNYsHVP-ITFaq 3088 Anopheles gambiae...
Q555C6   5252 SWK----WSGGMRIDQI-GVNYIKLQH--Qh-dDLIeqSIKVEVRDTSESTMVYFYSNDPQnLPFHIKNEtKTI-ISYQQ 5322 Dictyostelium dis...
A0C9X9   2537 DYQ----SSSRLNISAI-GILYYQLRRkdQ---PKErlYFSCDIRQEGCSLYIIFNQLPQDqAPYKIELPvENLeLEIPE 2608 Paramecium tetrau...
Q22YP6   3038 DWK----WSGNMNVLEL-GTVNFMIRN--Qe-nKMDvsFLRTDVRSDDSNIYIVVEKVTEKeRPYVIQNYsKNFkIELKD 3109 Tetrahymena therm...
BAD32230  992 NCI----WSGGFEVNKN-NSFHINMRD--T---LGKcfFLRVEITLRGATYRISFSDTDQLpPPFRIDNFsKVP-VVFTQ 1060 house mouse

Q54LB8   2681 R-------------DSPENIDYIEPKEKLCYGWDEPSAEY 2707 Dictyostelium discoideum
O42926   2325 KrpdpesvdsrflqGSRSMKYALNPGEEANYSWDFPILKS 2364 Schizosaccharomyces pombe 972h-
P87319   2379 Vnpidas--egknnTALLKYHDIPPHSEVKYSWDYPCCAN 2416 Schizosaccharomyces pombe 972h-
Q9VU08   3059 Lrs---------kpV---WITPVRPQSSLSYVMDDPLGQQ 3086 fruit fly
Q171S2   3056 Raspr------ienH---LKSYVRPHSSIAYVLDDPLGYQ 3086 yellow fever mosquito
Q7Q1I0   3089 ad---------mkaT---FKTVVRPQCSIAYVLDEPTGAP 3116 Anopheles gambiae str. PEST
Q555C6   5323 K-------------HPNSKKYTLKPNEDRYFTWDFPSGER 5349 Dictyostelium discoideum
A0C9X9   2609 Ldvi-------lnsN----------NQVTYFAWDDPQRLQ 2631 Paramecium tetraurelia
Q22YP6   3110 Lniil------ppnE--KEDKTVDEHHQYYFSWENPFEKe 3141 Tetrahymena thermophila SB210
BAD32230 1061 Hgv-----------aePRLRTEVKPMMSLDYAWDEPTLPp 1089 house mouse
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