Conserved Protein Domain Family
DUF1170
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pfam06663: DUF1170 (this model, PSSM-Id:284152 is obsolete and has been replaced by 461979)
Protein of unknown function (DUF1170)
This family represents a conserved region of unknown function within MAGUIN, a neuronal membrane-associated guanylate kinase-interacting protein. This region is situated between the pfam00595 and pfam00169 domains. All family members also contain an N-terminal pfam00536 domain.
Links
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Statistics
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PSSM-Id: 284152
Aligned: 20 rows
Threshold Bit Score: 202.677
Created: 13-Jul-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q8BMA3        334 LKKEKPAILDLYIPPPPAVPYSPRDENVSFGYRGHSKSkqPLPVRKGSESPNSFLDQESQRRrFTIADS---DQLPg-YS 409  house mouse
XP_007232667  334 sRKEKPAILDLYIPPPPSVPYTPREVRTSSFSNVNNRP-------KGSESPNSFLDLESRRR-FTIAEY---DKLSv-YP 401  Mexican tetra
CAG09880      344 aKKEKPAILDLYIPPPPPVPYAPREVRMDTVSSISQRP-------KGSESPNSFLDLENRRR--TVTDY---DKLNfgCP 411  spotted green...
XP_006626259  389 IKKEKPAILDLYIPPPPAVPYTPRDVKGHKYAGVTARP-------KGSESPNSFLDLESRRR-FTIADY---EQLg-vCP 456  spotted gar
NP_001107119  335 rRPEKPAILDLYIPPPPSVPYSPRDAEKSEYAGVKMRP-------KGSESPNSSLDLANRRR-SNISDY---NNKPtvQP 403  zebrafish
XP_004082424  334 TKREKPAILDFYIPPPPQVPYTPREMRADTVSSINKRP-------KGSESPNSFLDQEGRRH-GSITDY---DKLNpgRP 402  Japanese medaka
XP_007255596  334 VKKEKPAILDLYIPPPPAVPYAPRDVKSSVCSGVTMRT-------KRHESPNSSLDRAGRRR-SNLSDYianQPVIvvPP 405  Mexican tetra
XP_012356319  341 TKRDSSALQDLYIPPPPAEPYIPRDEKGNLPCEDLRGHmvGKPVHKGSESPNSFLDQEYRKR-FNIVEE---DTVLycYE 416  northern whit...
XP_006627810  341 SKRDSSALQDLFIPPPPSEPYTPRDDKGNLPSDDITRHhaGIPVAKGSESPNSFLDQEYRKR-FTVLEE---DAVLycYE 416  spotted gar
XP_007252378  341 SKRDSSALQDLYIPPPPAEPYTPRDEQGNLPCDERGQG--GIPAAKGSESPNSFLDQEYRRR-YPLMEE---EAVLycYE 414  Mexican tetra

Q8BMA3        410 VE-TNVLPTKMRGKTPSYGKPRPLSMPADGNWMGIVDPFAKPRGNGRKGEDALCRYFSNERITPITEESASPMYRFSRPL 488  house mouse
XP_007232667  402 VE-ANVVQTRLRERSSSRGKPRPLSMPAD-TCLNVTDPCARPWTQGRKGEDLLYRYLSNERIPTIAEEIPSTGRSYKSP- 478  Mexican tetra
CAG09880      412 IE-ANVIQPKMREPKPSRGKPRPISMPAD-TCLRVTDPYARPWAQGRKGEDLLYRYLSNERIPTIAEELPSVSPPY-RPA 488  spotted green...
XP_006626259  457 AG-APALPARMRERTSSHGKPRPLSMPVDGSCLGPMDNCSKPWTAGRKGEDALYRYMSNERIPPIIEESPSVHQLY-RPA 534  spotted gar
NP_001107119  404 AE-AAVPQARMRQRTPSRGKPRPVSMPVD-TCLGMSDSPSRPWALGRKGDELLHRYLSNEQIPTISEESPCYPLPY-RPA 480  zebrafish
XP_004082424  403 TD-AGMMQPRMREHKPSRGKPRPLSMPVD-ACVTVADSYVKPWAQARKGEDPLYRYMSNERIPTIAEEVLSGSPSF-RPA 479  Japanese medaka
XP_007255596  406 PE-PVVPQARLRQRTPSRGKPRPVSMPAD-ACLGLSHSPCPPRGLGRKGEDALRRYLSNERIPTISEESPCYPVPY-RPT 482  Mexican tetra
XP_012356319  417 YEkGRSSSQGRRESTPTYGKLRPISMPVEYNWVGDYEDPNKMKRDSRR-ENSLLRYMSNEKI---AQEEYMFQRNSKKDT 492  northern whit...
XP_006627810  417 YDkGR--GPSRRDATPTYGRLRPISMPVEYNWVGDYEDPSKMKREGRR-ENSLLRYVSEDKAP---PEEYMTQRSSKRDT 490  spotted gar
XP_007252378  415 YDpSRGAPPSRRESTPTYGRLRPISMPVEYNWVPDYEDPARLKREGRR-ENSMLRYVSEDKVP----EEYLTGRSAKRDT 489  Mexican tetra

Q8BMA3        489 TERhLVRgADYIRGSRCYINSDLHSSATIPFQEE---GSK--KKSASSSAKASSGEPSLLVS 545  house mouse
XP_007232667  479 GER-CVRgVDHVRNSRFLVNVDLHNSATIPYQED---FTK--KTPMTSTPKRPPTEPSLLVS 534  Mexican tetra
CAG09880      489 GERhLIR-VDHIRGNRYFSNSDLHNSATIPYQED----AR--KAPVAPVTKRTSAERSLLVS 543  spotted green pufferfish
XP_006626259  535 TDRhLIRaADHFRGSRYFTNADLHNSATIPYQEDspkKSP--GSSSSSSSRTASAEPSLLVS 594  spotted gar
NP_001107119  481 GERqLVRgVDHIRGSQCFINADLHNSATIPYQEA---VAR--K-PASKSSKRPPSEPSVFSS 536  zebrafish
XP_004082424  480 GGRhLVR-VDHIRGNRFYSNTDLHNSSTIPYQED----IK--KAPVAPFSRRKSAKRSLLDS 534  Japanese medaka
XP_007255596  483 GAR-LVRgVDHIRGSQCFINADLHNSATIPYQEA---VAR--KK-TSKSSKRPPSESSLFSS 537  Mexican tetra
XP_012356319  493 ----------LQCGAPVPETTLYHTFQQSSLQHK---SKKknKGPIAGKSKRrisckdlgrg 541  northern white-cheeked gibbon
XP_006627810  491 GRR----------------------------------SKK--KGDKGGSPSHYALLPAlqme 516  spotted gar
XP_007252378  490 GKR----------------------------------TKK--KSEKSGSPAHYSLLPAlqme 515  Mexican tetra
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