1M1J,1DEQ


Conserved Protein Domain Family
Fib_alpha

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pfam08702: Fib_alpha (this model, PSSM-Id:285864 is obsolete and has been replaced by 312286)
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Fibrinogen alpha/beta chain family
Fibrinogen is a protein involved in platelet aggregation and is essential for the coagulation of blood. This domain forms part of the central coiled coiled region of the protein which is formed from two sets of three non-identical chains (alpha, beta and gamma).
Statistics
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PSSM-Id: 285864
View PSSM: pfam08702
Aligned: 72 rows
Threshold Bit Score: 149.977
Threshold Setting Gi: 768942638
Created: 13-Jul-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1M1J_E        67 AGGCKHPLDELGVLCPTGCELQTTLLKQEKTVKPVLRDLKDRVAKFSDTSTTMYQYVNMIDNKLVKTQKQRKdNDIILSE 146
gi 542247305  41 KEWPFCTDVEWGPKCPSGCRIQGLMEKYDHNMLKKIEKIRSLLDQNKAKHRSADTVSKQTYDYLKEKLTTDAgYDNNYFD 120
gi 47207198   43 KEWPFCSDDDWGPKCPSGCRIQGLMDKHDFSLLKKIEKIRNLLDQNKAKFRTADQASKQTYDYLKDKLTLDSdNSNKYYA 122
gi 224049651  50 KSWPICADDDWGTKCPSGCRMQGLIDEKDQEFSHRIDKIKKLLSDNQNNHKKSNQIIVETVNALKPNLDSAQeLDETYGR 129
gi 551518639  42 REWPFCTDDDWYSKCPSGCRIQGLMDKNDHELLKKIAKIRSLLDQHKARHRSVDLVSKQTYDILTEKLTLDTgNDNMYYN 121
gi 327274039  50 KSWPTCSDEEWGIKCPSGCRMQGLIDETDREFNDRINKIKKLLSDNQNSYKKSNILKQELTSFLERNLVDEQeLDNGYGQ 129
gi 429484490  50 KNWPICVDDDWGTKCPSGCRMQGIIDDTDQNYSQRIDNIRQQLADSQNKYKTSNRVIVETINILKPGLEGAQqLDENYGH 129
gi 303304954  46 KEWPGCTDDDWGSKCPSGCRVQGLMDKADHDLLKKIEKIRRLLVEGQKLYRSADEVSKTTYTYLREKLTSNSgYDNRYMS 125
gi 512816023  51 KNWPICSDEDWGPKCPSGCRLQGLVDKTDKDFAKRVETIKQKLKDGESSHKSIDLKTKQTYQFLKDNLVQAQqSDGKYNQ 130
gi 573882839  48 KEWPICLDEDWGPKCPSGCRIQGLLTKADKDLADKIDKIRKFLDENRNKYRSADQITKTTYDVLREKLVLNTgADNRFQN 127
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
1M1J_E       147 YNTEMElHYNYIKDNLDNNIpSSLRVLRAVIDSLHKKIQKLENAIATQTDYCRSPCVASCNIP 209
gi 542247305 121 LAQTLRqRITDMKIKIDRQV-TVLAALRDRVKDQVIEMQRLEVDIDIKLRSCKGSCAGYSEYQ 182
gi 47207198  123 LAQNLRrNINDMKIKIDAQL-RALAALKDRVRDQVSEMQRLEVDIDIKLRSCKGSCERYSAYQ 184
gi 224049651 130 LSGELRrRIMTLKQRVVTQV-NRIKALQSSIQEQVVEMKRLEVDIDIKIRACKGTCAKSFDYk 191
gi 551518639 122 LAQTLRqRITEMKVRIDRQH-KALAALKARVKDQVVEMQKLEIDIDIKLRSCKGSCGAHTVYQ 183
gi 327274039 130 ISDDLRrRLVTLKQRVFNQV-NRIKVLQNTIRNQVGELKRLEVDIDIKIRACKGSCARTYNYH 191
gi 429484490 130 VSTELRrRIVTLKQRVATQV-NRIKALQNSIQEQVVEMKRLEVDIDIKIRACKGSCARSFDYQ 191
gi 303304954 126 LAEQLRqRITDIKIKIDRQL-RLLDALKSQVKDQVVVMQRLEVDIDIKLRTCKGSCASYSEfs 187
gi 512816023 131 VSEDLRkKIEYLKLKVSNQV-ERIKALQKNIRDQVVEMKRLEVDIDIKIRACKGSCAKNTDYk 192
gi 573882839 128 LADQLRqRIIEMKLKIDQQN-SLLIALKSRVRDQVNEVHRIEVDIDIKIRSCKGSCASAHEYt 189
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