Conserved Protein Domain Family
BUD22
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pfam09073: BUD22 (this model, PSSM-Id:286199 is obsolete and has been replaced by 401132)
BUD22
BUD22 has been shown in yeast to be a nuclear protein involved in bud-site selection. It plays a role in positioning the proximal bud pole signal. More recently it has been shown to be involved in ribosome biogenesis.
Links
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Statistics
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PSSM-Id: 286199
Aligned: 72 rows
Threshold Bit Score: 60.1848
Created: 27-Jun-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q04347        84 THLSKCIKEQIQKISKKNSSKVk--DAQ-KNKSPSIDIEKmlatqlslddlaLFMTRFRLI--------KILHQRIKQKS 152 Saccharomyces c...
Q6BP11        65 KKLNKEVNKHIKSDLNKWKNV--------DSKNGLLEFFGaed-------riQELITSKLI--------KCITSSILITK 121 Debaryomyces ha...
CCE41699      64 eqkyhsayiklekETKRYVKQKk--APDvFNQNDFI----------------SQLITAKLI--------KCITSTILLTK 117 Candida parapsi...
XP_001385878  65 KKLEKEINKVVKTEISKLk------QDKtKNQS-TINFLEsge-------nvKLLITSKLV--------KSLTTSILINK 122 Scheffersomyces...
XP_006689426  74 VKLRSEVKKTVKADLHKLGKKa-------DENKQVLEFLQndn-------liEDMVVSKVI--------RILQAAVLNNK 131 Candida tenuis ...
EMG48941      54 eidslkseifqkkyhsgytklLk--EVNkKPVPVKEDDFV------------QKLITAKLI--------KSIQSSILNSK 111 Candida maltosa...
XP_004204668  75 TKLKRHINNQASNDLSKWKRNGt--EKEvAEFLSKAEVID------------N-IIKSRLI--------KCMINVFLTKK 131 Pichia farinosa...
XP_002638663 141 VGLRATVTKAKDQWISKVIRKKk--EL--EKKRKEGKGGKeevvdaklnrmmEEILALKTIdrdtiakfASLNTKTLNEL 216 Caenorhabditis ...
XP_001527710  72 KKLDKEVRRLTKQKTKKDVPEVfnne-----------------------efiNQLITSRLI--------KSISSTILTNK 120 Lodderomyces el...
XP_002491434  75 VKMQRNLKKVIKSETSKCQAKLktsPDD-AKQQERLQILQdi--------dlDDIINRKLI--------RILINVFTPTE 137 Komagataella pa...

Q04347       153 KKI-EGdt----------nNK--------TWLnnndysgyindktskwnpsniwnEVITKLPSCEKLNALIGQSKIVQNL 213 Saccharomyces c...
Q6BP11       122 DLK-S--------------VP--------PKYmpsdvcsiitdkshksnpsaffiNYCQTNKDLNNYISNLWNTKSIKPL 178 Debaryomyces ha...
CCE41699     118 HLK-TNppa-------yipEN--------ISKyildkssp-------fnpshffvQYCQSSKEVNNYCSNLWNSKAVKSV 174 Candida parapsi...
XP_001385878 123 DLK-LNppnyisedvreiiLD--------KSNianps--------------kffiQFCQNDKNLNNYFSNLWNNKSIKSI 179 Scheffersomyces...
XP_006689426 132 TAR-ENppkfidpqvlqviGD--------KQHssnpt--------------kffkDHCQNNKELHKYVSSLWNLKGMKLV 188 Candida tenuis ...
EMG48941     112 ELK-SNppqyiskevrdiiTD--------KENdsnps--------------kfyiKYCQNDKEVNKFVANLWNNKNVKKL 168 Candida maltosa...
XP_004204668 132 DGKlTAps---------fiSAdtreamtnKQHelhps--------------aifkSYFQSNKELNNYFSNIWNTKTFKRL 188 Pichia farinosa...
XP_002638663 217 KID-GSt------------------------------------------------------PMAEQVMYKLACHEVVVSR 241 Caenorhabditis ...
XP_001527710 121 ELK-A--------------NP--------PVYikdsvrdtikdkanpcnpsqffiAHCQNSKEVNNYCSNLWNTKEMKTI 177 Lodderomyces el...
XP_002491434 138 ELQ-E--------------FP--------PTYlptwvidsik---dknskynpnnTTKGDSQAKINIVSQLMNNKELREI 191 Komagataella pa...

Q04347       214 TESFDL-SI---CLIF-------------------------------------------------Gfdvsamk--akkyg 238 Saccharomyces c...
Q6BP11       179 LSEIEW-SF---KMVR-------------------------------------------------Gdlt---------kf 196 Debaryomyces ha...
CCE41699     175 VDDIEW-SF---RMVR-------------------------------------------------Gnlskqe----feer 197 Candida parapsi...
XP_001385878 180 ISEIEW-SF---KIVR-------------------------------------------------Gnlttqekdarrkat 206 Scheffersomyces...
XP_006689426 189 LAEIEW-SF---RLVR-------------------------------------------------Gnlteqe----innr 211 Candida tenuis ...
EMG48941     169 LDEIEW-SF---KIVR-------------------------------------------------Gdlt---------kq 186 Candida maltosa...
XP_004204668 189 AEDIEW-AF---KQVRggittqeknarksvtkeldgsvkgesdlssdsdsdfdseddsennsgdgGdnkthk----slkd 260 Pichia farinosa...
XP_002638663 242 IQAIKQkYIewnKTAA-------------------------------------------------Ffmqrlg---rqyst 269 Caenorhabditis ...
XP_001527710 178 LNDIDW-SF---RQVR-------------------------------------------------Gslt---------kt 195 Lodderomyces el...
XP_002491434 192 LSTIDL-TL---RLVE-------------------------------------------------Gpverpdq--ikekr 216 Komagataella pa...

Q04347       239 aREKTANANQTH--------------------------------------S-------------------------NIDY 255 Saccharomyces c...
Q6BP11       197 eRDARKKL--------------------------------------------------------------------VGKD 208 Debaryomyces ha...
CCE41699     198 rKQKGRAANEDD--------------------------------------S-------------------------NAGD 214 Candida parapsi...
XP_001385878 207 gREISDDEKEASigdsevseddddedhheqeeedmeeldtegvyekfaiyD-------------------------KLVG 261 Scheffersomyces...
XP_006689426 212 rTATGKSIKKDN--------------------------------------D-------------------------ENSD 228 Candida tenuis ...
EMG48941     187 eRDARSKITGKN--------------------------------------VdeeveedddessddeeedddnesdiDLEK 228 Candida maltosa...
XP_004204668 261 iAASSRDTQDDE--------------------------------------S-------------------------DSSD 277 Pichia farinosa...
XP_002638663 270 kPEKKEKKAKHS--------------------------------------D-------------------------ETKG 286 Caenorhabditis ...
XP_001527710 196 eLEERSRQ--------------------------------------------------------------------TGKA 207 Lodderomyces el...
XP_002491434 217 eKREKKKS-DDK--------------------------------------D-------------------------TATT 232 Komagataella pa...

Q04347       256 -------------------------------------DTDD----------GNEKNAIDSksnaigaqtqSNKEtTSDNE 288 Saccharomyces c...
Q6BP11       209 -------------------------------------IQSD----------FDEDNNEDVq---------DDSDdDMVEG 232 Debaryomyces ha...
CCE41699     215 -------------------------------------N------------------------------------------ 215 Candida parapsi...
XP_001385878 262 -------------------------------------D------------------------------------------ 262 Scheffersomyces...
XP_006689426 229 seddgsdddsgsdtedendesapadfekfavydnlvvD------------------------------------------ 266 Candida tenuis ...
EMG48941     229 -------------------------------------E------------------------------------------ 229 Candida maltosa...
XP_004204668 278 -------------------------------------Efaeyd------------------------------------- 283 Pichia farinosa...
XP_002638663 287 -------------------------------------IQKAktdsenvvdsGEESDVEEDal-------dDSEDvEKEEE 322 Caenorhabditis ...
XP_001527710 208 -------------------------------------SDTG----------DNEGTGTDEessseganseDDESsDEDDG 240 Lodderomyces el...
XP_002491434 233 -------------------------------------IKKS----------EKNSSYSDNeae----dqdQDEDsDHSDL 261 Komagataella pa...

Q04347       289 D----------------------------LLIKEYeGmLGSSG--------DEGEGgg---------------------- 310 Saccharomyces c...
Q6BP11       233 Dsskghekeigd-------desidaeeifDKFAVYdNlVNNSD--------DEEQKf----------------------- 274 Debaryomyces ha...
CCE41699     216 -----------------------------------------TS--------DETSEesggelsdedqiaafdgmvagsdq 246 Candida parapsi...
XP_001385878 263 -----------------------------------------SD--------NEDEEqa---------------------- 271 Scheffersomyces...
XP_006689426 267 -----------------------------------------SD--------QEDEGp----------------------- 274 Candida tenuis ...
EMG48941     230 -----------------------------------------YDnfavydnlEEGSDvdq--------------------- 247 Candida maltosa...
XP_004204668 284 ------------------------------------nlvqgSD--------SEDNDees--------------------- 298 Pichia farinosa...
XP_002638663 323 Egedapddyd-----------------------qsdvemvdSD--------DEDVGve---------------------- 349 Caenorhabditis ...
XP_001527710 241 TsssglehegkdgihngiqddgsdideelEAYAQYdKwVVASD--------QEDIDekqe-------------------- 292 Lodderomyces el...
XP_002491434 262 Dd---------------------------INFSKYdGaLAASS--------DEDSD------------------------ 282 Komagataella pa...

Q04347       311 -----------yLNPNINYNEVTDEEPSEASSDEDDSDE-----------------RFS---------DSEENEPr---- 349 Saccharomyces c...
Q6BP11       275 -----------dLDPNVNYNEVTDEESSDLEDDIDVSAGnsdd---------sffeDDV---------RQEAkt------ 319 Debaryomyces ha...
CCE41699     247 eeedddeekengLDPNIDYNEVTDEEPSEAASGESSHDSg----------------SEI---------DLGDDFFe---- 297 Candida parapsi...
XP_001385878 272 ----------pdLDPSINYNEVTDEEPSDESEEDEELDSd----------------SSS---------DDGFFE------ 310 Scheffersomyces...
XP_006689426 275 -----------qLDPKINYNEVTDEEPSEESSGDDTSGSd----------------VEDvvdnkktksTKKPKDDf---- 323 Candida tenuis ...
EMG48941     248 ---------tpdLDPSINYNEVTDEEPSEDESSESESESs----------------HDD---------FFEEEEEe---- 289 Candida maltosa...
XP_004204668 299 ---------nqgRSNEVNYNEVTDEESEDELSEDELSPNt----------------SDE---------EDDSEKDv---- 340 Pichia farinosa...
XP_002638663     --------------------------------------------------------------------------------     Caenorhabditis ...
XP_001527710 293 --------eefeLDPNVNYNEVTDEEPLEDDEEYSGDESdptdeaedkdeqqqqheEEE---------EEEEDDDdssvd 355 Lodderomyces el...
XP_002491434 283 ------------------------DEPATQKKDTSRSLVeddf----------fdfSVA---------ELKQREKadak- 318 Komagataella pa...

Q04347       350 -----------rKKPKLH------------NLPELMAGYYSGNDTEeesdednknvkgkkkkrD----TAED--Rtare- 399 Saccharomyces c...
Q6BP11       320 ----------ssKREy--------------KLPELANGYFSGGSDDed--------------dE----IDND--Kvvke- 354 Debaryomyces ha...
CCE41699     298 -----------eEPPKKKskanp---dykyNLPELAQGYYSGGSDD-----------------E----SDDI--Dnddv- 339 Candida parapsi...
XP_001385878 311 --------------QDESskkstkkekkdyNLPQLASGYFSGGSDD-----------------E----GEDV--Dndkv- 352 Scheffersomyces...
XP_006689426 324 -----------fASDSESdsedaqsvekkyNLPELTTGYISGGSDD-----------------EgdfqVDDD--Rvvkq- 372 Candida tenuis ...
EMG48941     290 -----------qPAKKKQkkde-----styKLPELASGYFSGGSDD-----------------E----DDADndKvvke- 331 Candida maltosa...
XP_004204668 341 -----------nKEKKKEkkns-----kpyKLPELAVGYFSGDSDD-----------------D----IADV--Ddddv- 380 Pichia farinosa...
XP_002638663 350 -----------aAKKRRNmllnligvkedaSRPAL----------------------------N----PKKR--Kivddd 384 Caenorhabditis ...
XP_001527710 356 dffeeeppkkksKKTKETkdde-----tryKLPALATGYYSGGSDDede------------igD----VDND--Rvvke- 411 Lodderomyces el...
XP_002491434 319 ---------kkeQKLEKEy-----------NLPQLTSGYFSGGESDg----------------D----YDND--Kvvqe- 355 Komagataella pa...

Q04347       400 qmsNEPK-----RKNRRGQRARRKIWEK--------KYGSQAKH-VQR-------------------------------- 433 Saccharomyces c...
Q6BP11       355 attQ--------RKNRRGQRARQKIWAQ--------KYGKEAKH-VKE-------------------------------- 385 Debaryomyces ha...
CCE41699     340 vksITQQ-----RKNRRGQRARQKIWAQ--------KYGKEAKH-IVKnieriqseretrqreyeerqrkrelkakllae 405 Candida parapsi...
XP_001385878 353 vkdITTQ-----RKNRRGQRARQKIWAQ--------KYGREAKH-VKS-------------------------------- 386 Scheffersomyces...
XP_006689426 373 vtsQ--------RKNRRGQRARQKIWEQ--------KYGKTAKH-KQK-------------------------------- 403 Candida tenuis ...
EMG48941     332 lttQ--------RKNRRGQRARQKIWAQ--------KYGKEAAH-IKK-------------------------------- 362 Candida maltosa...
XP_004204668 381 vreATTK-----RKNRRGQRARQKLWAK--------KFGKEATH-IKKkid----------------------------- 417 Pichia farinosa...
XP_002638663 385 sqdVTETtssepSKKQKTKEAMKAVLEKalkaekveKPKKMVPKkVEV-------------------------------- 432 Caenorhabditis ...
XP_001527710 412 ltqQ--------RKNRRGQRARQKIWEK--------KYGSKAKH-IVK-------------------------------- 442 Lodderomyces el...
XP_002491434 356 atkP--------RKNRRGQRARQKIWEA--------KYGRNANH-VLK-------------------------------- 386 Komagataella pa...

Q04347       434 -------------ELEK-EMEDRKQrqi-----------------------------------------eyeARVakreA 458 Saccharomyces c...
Q6BP11       386 -------------EQVI-IASERERkrl-----------------------------------------eyeERCkkreL 410 Debaryomyces ha...
CCE41699     406 kqqptganteplgERKS-K------------------------------------------------------------- 423 Candida parapsi...
XP_001385878 387 -------------EIEK-A------------------------------------------------------------- 391 Scheffersomyces...
XP_006689426 404 -------------ESEAyE------------------------------------------------------------- 409 Candida tenuis ...
EMG48941     363 -------------NIQR-V------------------------------------------------------------- 367 Candida maltosa...
XP_004204668 418 -----------haQQER-E------------------------------------------------------------- 424 Pichia farinosa...
XP_002638663 433 -------------SSEV-ESEDVEEeaddveeeedpnqqtlvmkidlsqggkiakstaapkstmaahapkkaSED----V 494 Caenorhabditis ...
XP_001527710 443 -------------DKER-IQNEREIrqk-----------------------------------------eyeERQrkreL 467 Lodderomyces el...
XP_002491434 387 -------------EHDR-IRSEREQkqa-----------------------------------------eyeERVrkraA 411 Komagataella pa...

Q04347       459 KAASLEasrsrereDRRT-----------------------------------------------------------ETN 479 Saccharomyces c...
Q6BP11       411 KAKINSap----tgSNTAplaerrprt-----------------------------------------ntedpvekpVEI 445 Debaryomyces ha...
CCE41699         --------------------------------------------------------------------------------     Candida parapsi...
XP_001385878     --------------------------------------------------------------------------------     Scheffersomyces...
XP_006689426     --------------------------------------------------------------------------------     Candida tenuis ...
EMG48941         --------------------------------------------------------------------------------     Candida maltosa...
XP_004204668     --------------------------------------------------------------------------------     Pichia farinosa...
XP_002638663 495 EEENSEdessgfflPASSkgtssaskskavpesggiakkmeklgveedlkmkknkntkkkgpvgkknfqppatttenKKK 574 Caenorhabditis ...
XP_001527710 468 KAKLLAekqk-ptgSNMEplgerks---------------------------------------------rsangtrTAV 501 Lodderomyces el...
XP_002491434 412 KAAELRerq--------------------------------------------------------------------asM 423 Komagataella pa...

Q04347       480 N-------------------------------------------K----------------------------------K 482 Saccharomyces c...
Q6BP11       446 S-------------------------------------------K----------------------------------P 448 Debaryomyces ha...
CCE41699     424 A-------------------------------------------S----------------------------------V 426 Candida parapsi...
XP_001385878 392 AsdrerrrleyeercrkreeknnlaptgsntaplgdrkvrngvsP----------------------------------A 437 Scheffersomyces...
XP_006689426 410 N-------------------------------------------D----------------------------------K 412 Candida tenuis ...
EMG48941     368 A-------------------------------------------S----------------------------------E 370 Candida maltosa...
XP_004204668 425 K-------------------------------------------KqkefeererrrqlkrqrendneysskpsdsstsrE 461 Pichia farinosa...
XP_002638663 575 G-------------------------------------------T----------------------------------S 577 Caenorhabditis ...
XP_001527710 502 G-------------------------------------------V----------------------------------V 504 Lodderomyces el...
XP_002491434 424 P-------------------------------------------P----------------------------------P 426 Komagataella pa...

Q04347       483 E--------------------------------------------KESASTGEEHPSWIAKRLAEEKLQKAKFEGKKIKF 518 Saccharomyces c...
Q6BP11       449 V--------------------------------------------EISKPVEKEHPSWVAKRLAEEKQKNARFQGTKIKF 484 Debaryomyces ha...
CCE41699     427 T--------------------------------------------PPPAEEKKIHPSWEAKKLAEEKLKNVKFQGKKITF 462 Candida parapsi...
XP_001385878 438 P--------------------------------------------GPPSDTTKMHPSWEAKKLAEEKLKNVKFQGKKITF 473 Scheffersomyces...
XP_006689426 413 Krrqsefeereqkrrsraq--------ealenapsgsnltpigrkQQDKPKKEEHPSWIAKKKEEEKLKNLKFTGKKITF 484 Candida tenuis ...
EMG48941     371 ReqrqleyeerqrkremkakmleekqtganalplgerkaaqpqlqSQPVEPKSIHPSWEAKQKEKEKLKNITFQGKKVVF 450 Candida maltosa...
XP_004204668 462 P--------------------------------------------ESNSRIDINHPSWEAKKKAEEKIKNAKFQGKKLKF 497 Pichia farinosa...
XP_002638663 578 K--------------------------------------------NSTSSEGQMHPSWLASQAKKKELAAAKPAGKRILF 613 Caenorhabditis ...
XP_001527710 505 G--------------------------------------------AAPAAEKLLHPSWEAKKQAEAKMKNVKFQGKKITF 540 Lodderomyces el...
XP_002491434 427 K--------------------------------------------IQKVASKGLHPSWEAKKNLEKKQKNIPFQGKKVTF 462 Komagataella pa...

Q04347       519 D 519 Saccharomyces cerevisiae S288c
Q6BP11       485 D 485 Debaryomyces hansenii
CCE41699     463 D 463 Candida parapsilosis
XP_001385878 474 D 474 Scheffersomyces stipitis CBS 6054
XP_006689426 485 D 485 Candida tenuis ATCC 10573
EMG48941     451 D 451 Candida maltosa Xu316
XP_004204668 498 s 498 Pichia farinosa CBS 7064
XP_002638663 614 N 614 Caenorhabditis briggsae
XP_001527710 541 D 541 Lodderomyces elongisporus NRRL YB-4239
XP_002491434 463 D 463 Komagataella pastoris GS115
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