Conserved Protein Domain Family
DUF3373
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pfam11853: DUF3373 (this model, PSSM-Id:288686 is obsolete and has been replaced by 432131)
Protein of unknown function (DUF3373)
This family of proteins are functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 472 to 574 amino acids in length.
Links
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Statistics
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PSSM-Id: 288686
Aligned: 28 rows
Threshold Bit Score: 515.326
Created: 28-Jun-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
Download Cn3D
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q8E9W9         1 MR-TLI-SILVANaLFMSGQAFAA--ANNtqadtqkmAELKQQLTDITEQLDELNSRVDKTE------------------ 58  Shewanella onei...
Q7MSA6         4 sR-TKV-SLILAS-LLTSGVVYAA--DAQ--------VDLAKEIEALKAELNELKATVKNSN------------------ 52  Wolinella succi...
WP_012083203   1 MK-KWI-ALSAVA--AMATMSFASgsANN--------DDLRAELEQLKQQINELKQAQAKIN------------------ 50  Nitratiruptor s...
WP_025346302   1 MK-KLI-APLLIG-AALSS---AF--GAD--------DSLKQEIEALKVQMAELKNAQSKIN------------------ 46  Sulfurospirillu...
WP_013504803   1 MR-KII-SISLAI-AATASMSYAQ--ANT---------ELQELRQQIQQLEQRQQELEKQRF------------------ 48  Desulfurispiril...
WP_013459098   1 MKqRIL-GSVITA-ALLTTNAFSD--DSLiq----rfEKMEREMAALKAELESIKAENSRLStqlstpsntnskqd---- 68  Sulfuricurvum k...
WP_013326203   1 MK-KPL-LLSLAT-IAILGTTNVS--AESmyd---rfQAMELEMKKMKKELDELKAKQNAVAaadeeededevssdnket 72  Sulfurimonas au...
WP_012663627   1 MK-KLLlSATVVA-GLFAAPTI---------------DTLQKQINDLQQQLKELKAKQTEQN------------------ 45  Nautilia profun...
BAF71004       1 MK-KIV-SLSVMA-AAATSFAFGS--TAD--------D-----IANLQAQIDKLKVKQGKINa----------------- 45  Sulfurovum sp. ...
WP_013010954   1 MK-KII-SLILLV-LVPASFAFAA--DVTl-------EELKSQITELQDEVLKMSRRVDKNE------------------ 50  Denitrovibrio a...

Q8E9W9        59 ------------------------R------------HTSLDRLEITGDFRTKAHSLHYRDVVWnpainvnfndfgakam 102 Shewanella onei...
Q7MSA6        53 ------------------------FdgmqrelsaikkATYGDNLKFSADYRYTIDSIEYKHISG---------------- 92  Wolinella succi...
WP_012083203  51 ------------------------LkalkkqireikaHDAGDNIKWNVDFRTAYDVIGYKYASG---------------- 90  Nitratiruptor s...
WP_025346302  47 ------------------------IdalkaqvseikaHDAGDNIKWTVDFRTAYDVVDYKLHNAp--------------- 87  Sulfurospirillu...
WP_013504803  49 ------------------------Dqrls----rveaQAMGDNLKFDVDYRVTMDSLKYKLHSG---------------- 84  Desulfurispiril...
WP_013459098  69 ----------attsaninetlediQdqis----tinkKTNGDNLKFGVDFRTSVDNLHYKMADG---------------- 118 Sulfuricurvum k...
WP_013326203  73 asaddeedegedeemtveeqladiQdtls----dlnkNTNGNHIKFNVDYRFAVENLQYKMADG---------------- 132 Sulfurimonas au...
WP_012663627  46 ------------------------Dryyk----kvapIVANNHLFWSYDLRTTYDAIFQETTDGmgvtnvqmdpt----- 92  Nautilia profun...
BAF71004      46 -------------------------------------QSANDNIKWGVDFRTAYDNINYDMADG---------------- 72  Sulfurovum sp. ...
WP_013010954  51 ------------------------V------------HRIKDKVDIGVELRTRVDSISYKDVRAlpamgndmmglwlrgy 94  Denitrovibrio a...

Q8E9W9       103 sgvfgmpndpnspl------------------------------------------------------------------ 116 Shewanella onei...
Q7MSA6           --------------------------------------------------------------------------------     Wolinella succi...
WP_012083203     --------------------------------------------------------------------------------     Nitratiruptor s...
WP_025346302     --------------------------------------------------------------------------------     Sulfurospirillu...
WP_013504803     --------------------------------------------------------------------------------     Desulfurispiril...
WP_013459098     --------------------------------------------------------------------------------     Sulfuricurvum k...
WP_013326203     --------------------------------------------------------------------------------     Sulfurimonas au...
WP_012663627     --------------------------------------------------------------------------------     Nautilia profun...
BAF71004         --------------------------------------------------------------------------------     Sulfurovum sp. ...
WP_013010954  95 mintdadgnpanateswdtnnngfndafdpfaansvygqelyqfitdlaanpdvtgammtnpeitswmgtaevqtaignm 174 Denitrovibrio a...

Q8E9W9       117 -------------gkmmqanpdlaaafqngmlqgvmpyvlapkSVQDIDNDIFYTTRLRLNLKAKVWDNVSFAGRLSMYK 183 Shewanella onei...
Q7MSA6        93 ---------------------------------------------KKSKNDDFMSNRLILGMKYAPTDDLSFIGELSYNK 127 Wolinella succi...
WP_012083203  91 ----------------------------------------------TSSWNGIFTNRLWLGMAFAPTSNLVFKGLISYYK 124 Nitratiruptor s...
WP_025346302  88 -----------------------------------------------dQDNGIWTNKLILGMASQPADNLVFRGSLGAYK 120 Sulfurospirillu...
WP_013504803  85 ---------------------------------------------ATQENSSLLANRMILGMNFRPNDSVRFAGKLAYNK 119 Desulfurispiril...
WP_013459098 119 ---------------------------------------------STHKNDAVFSNRLWLNMGYAANKNISFTGQLAYNK 153 Sulfuricurvum k...
WP_013326203 133 ---------------------------------------------SKQENDAFMTNRLWLNMNWAATKNLSFTGQLAYNK 167 Sulfurimonas au...
WP_012663627  93 ---------------------------------tgqtvftfapVKGEKINNHIFTNRVILTGVYKPSDNLKATVRVEANN 139 Nautilia profun...
BAF71004      73 ---------------------------------------------SSVGNDSLLSMRLWLNMAYAPDSHNVFKGQLSMNK 107 Sulfurovum sp. ...
WP_013010954 175 mtnygasqmeaammvymqdmlssttlsatqlqmmktlfsnmkpRKYDHNNSSLFTNRLRIRLNSRVNDKLSFAGRLVMNK 254 Denitrovibrio a...

Q8E9W9       184 NWGDSTGVQVFDSWRSF---TMDGTSSGNTSGD-WLRVERAYFDW-KNI----N----GSEFYLSIGRRPSTYGPPshyR 250 Shewanella onei...
Q7MSA6       128 AFGDTDNHAQSNTQPGYa--NFDWVTNENATDN-TVKVKQAYFLY-KNDn---D----TIPYTASVGRRPSVNGYPlnlR 196 Wolinella succi...
WP_012083203 125 MYGQLPAPQQGFN-------YFDWIVNETPNPSgELRLKEAYWLY-FGDsflgA----DIPWTASFGRRPATDGLLasyR 192 Nitratiruptor s...
WP_025346302 121 AFGQTNMSSNGTMFQS-----FDWYGTQKPSDS-TIKLREAYFIY-TGDm---G----DIPYAASFGRRPSVDGFLanlR 186 Sulfurospirillu...
WP_013504803 120 AFGDTANHSQSNTDPGYa--NFDWVVNENPLDN-TLKVKEAYFHYaTSM----G----SVPFAASLGRRPSTDGFLahlR 188 Desulfurispiril...
WP_013459098 154 IFGERAQTTQSPAMEG-----FDWISGESAYDD-TLRVRSAYFLY-TDDelagL----EIPWTFSIGRRPSTEGHLinfR 222 Sulfuricurvum k...
WP_013326203 168 AFGARSGASDP-TNSSFe--TFDWIANENAYDD-TLRVRSAYFLY-KND----TfmgtDVPWTFSIGRRPSTNGHLvnlR 238 Sulfurimonas au...
WP_012663627 140 MFGSNDASNMMVNPFQ----NVPWVANETPDDI-NFRLKEAFFNY-Y------F----GDDLMFSAGRRPATNGYPanlR 203 Nautilia profun...
BAF71004     108 AFGADFGTANNKTRALSmggMFDWTGNEALTDN-SLKVRQAYWLY-LGDkafgA----DIPWTFSIGRRPSTTGFLanlR 181 Sulfurovum sp. ...
WP_013010954 255 VWSDASDVQWMDGSYKSm--YLDGNAGSVPTDD-KLHVERAYFVY-KNEi---G----DLGWHFSFGRRPSTFGPG---K 320 Denitrovibrio a...

Q8E9W9       251 EN---ELRGGTPsGHLVNFNFDGATLGYNLGeLTGI------E-GQIVRFCYGQGFESqwgn----------gemfG--- 307 Shewanella onei...
Q7MSA6       197 EN----DQAASPnSHLINVEFDGASFKFDLDkITDI------S-GMYFKICLGRGLTNakqrfsmd---gtdyaqnN--- 259 Wolinella succi...
WP_012083203 193 ED----QNPKSPlGHIINTEFDGASFKFNLEnVTGV------P-GMYFKLCMGRGMTNantr----------yafgTlpd 251 Nitratiruptor s...
WP_025346302 187 ND---NESPASPtSHNINMEFDGASFKFDMDkVTGI------S-GMYLKLCLGRGFSEttgsysmsssggfnasysE--- 253 Sulfurospirillu...
WP_013504803 189 EG---DSHYQSPlAHSINVEFDGASFTWQLEgLIGL------P-GSSFKICTGRGLTNanpr----------fdmmG--- 245 Desulfurispiril...
WP_013459098 223 DD----VKTSSPlAHAINVEFDGASAKFGTEeLTGL------A-GSYFKLCAGRGMSEaeprfss-----apytgnG--- 283 Sulfuricurvum k...
WP_013326203 239 DD----DHAASPmGHNINVEFDGLSSKFALEnVTGV------D-GMYVKFCAGRGMSNaapr----------fnsaP--- 294 Sulfurimonas au...
WP_012663627 204 EG---DD-PASPlAHLINMEFDGFSFKIGNGeFSKItdkfgdW-GTWLKFCAGRGYSSatgkwps----nfaapysR--- 271 Nautilia profun...
BAF71004     182 ED----DAAQSPlGHIINVEFDGLSSKLDLSnVTGV------A-GMSFKVCLGYGATNaeplftg-----ptpyadT--- 242 Sulfurovum sp. ...
WP_013010954 321 ENseyATLGGSPlSHIIQWQFDGASLQFDFEnLLEF------LpGSFIKICYGKGFESgwgssnam---aanngliA--- 388 Denitrovibrio a...

Q8E9W9       308 -----DIVT---KD------THLGGFNIDAINDGTNFLQFTLFGAKDVNDGFKGtmafptqlagif-----aptmyqdmq 368 Shewanella onei...
Q7MSA6       260 -----REDS---KH------VDMYGFVFVPYDDGQYHVLTNFAWAKDMIGYDQAgmnayqgaymawmmaptssnyydmiy 325 Wolinella succi...
WP_012083203 252 asytkVNGW---SN------TDLAGFIFVPYDDGQYSVHTTAFKAFNLPGYFASqyvwdat----------------lnt 306 Nitratiruptor s...
WP_025346302 254 -----DGET---PD------MDLAGVIWQIYDNGQYKVMANYFQAWNMMDMNIYdmqai-------------------pl 300 Sulfurospirillu...
WP_013504803 246 -----YDYA---KDeslhsnIDMLGFIFQPYSDGQYTVQTQAFKAWNLIGFTGAdmmayqnavgtf------mmdpdpnn 311 Desulfurispiril...
WP_013459098 284 -----SSKT---NN------IDMAGIIVVPYDDKQFSTGFQYTYANNLIDQEAPg------------------------- 324 Sulfuricurvum k...
WP_013326203 295 -----YADTtsnSA------IDLVGLIFTPWSDGQYTINSQYYYAGNLIDVKNSnd------------------------ 339 Sulfurimonas au...
WP_012663627 272 -----NDAL---KN------MDFAGFIFVPYDDGQYSLWTETVWAWHVQGYTMNydatv-------------------al 318 Nautilia profun...
BAF71004     243 -----ENNL---DD------IKLGGFIFEPYNDGQFIVKATWFKAWDLPGQqspmn----------------------pe 286 Sulfurovum sp. ...
WP_013010954 389 -----SPEV---DD------VEFLGVIVKFYDDDQYKLWYNFARGFGVTDGFTGaavmpftvvgqntd-lsadgsydeyq 453 Denitrovibrio a...

Q8E9W9       369 kfdNFNFVTRVQP-SGVIGDMYLGGIGFAREEan--------dIKWFASLGWTRAEPNGNagmfggmlsdavfeaelnst 439 Shewanella onei...
Q7MSA6       326 ktpQFK----------SVGDWNGGAITLGADGigedwgdfmdeTKAFVSWAFTKTKPQNGytml---------------- 379 Wolinella succi...
WP_012083203 307 ympDFTSFGLVQG-----GDMYGAAVSFLAQGigdgindflddTNAFVSFAWSKTLPGGThvgtfn---------ggpyn 372 Nitratiruptor s...
WP_025346302 301 asgG-TQYNPLFN-FADVGDLTGGSLALQVNGigdgisdflddSIFFLSYAYSKTDPNDNvig----------------- 361 Sulfurospirillu...
WP_013504803 312 lanNYVNMMMAQPsFSDVGDMYGATVSVLANGvgdfn-sfldnTKLFVSYAVSQTLPNDSmsml---------------- 374 Desulfurispiril...
WP_013459098 325 -----------GN-METVGGLHTATAFAMVNGigdgwseflddSLIFISGAVSKTDP----------------------- 369 Sulfuricurvum k...
WP_013326203 340 ---------qSQG-FKTVGNLHAITANFVANGigdgindflddTVFFISGAMSITDPDNgqsm----------------- 392 Sulfurimonas au...
WP_012663627 319 adpTKAVY----E-MSDTGNYFGENVMLKADGigdgisdflddTKAFVSFAYSKVKGNGKllgq-------------dst 380 Nautilia profun...
BAF71004     287 fdgNF----------HQFGDMQGAALSVLVDGltedg--yfadAKVFGSFAWSKSMP----------------------- 331 Sulfurovum sp. ...
WP_013010954 454 itpNYSGSSSRLEaTAEVGDMEWHSLLAQGETf---------gFSWFTSFAMSKSHPDGRsr----------------sa 508 Denitrovibrio a...

Q8E9W9       440 GTEIIMvpktsddtDTKDGYGIYVGIQIP----A-P-YGKFGLEYNYGSEYWTPFTQAQDDPIGSKLATRGHVGEAYYIF 513 Shewanella onei...
Q7MSA6       380 -----------gstESQTGHSWYAGIQVPal-vT-E-KGRIGVEWNKGSKYWRPVTYGEDTVIGSKLAARGTAWEVYYIQ 445 Wolinella succi...
WP_012083203 373 GVTTNVpnamlgstDNKSGTSIYVGANFPv--pMiD-GSRMGLEYNHGSKYWRSFTYAEDTLAGSKLAARGDAYEIWFNK 449 Nitratiruptor s...
WP_025346302 362 -ssaGPatgmlgrsDSETGSSIYTGVQVPg--iM-K-GQRLGVEYNHGSKYWRSFTYGEDTLVGSKLAARGDAYELYYIL 436 Sulfurospirillu...
WP_013504803 375 -----------gstDNKTGYSIWMGAEIPg--mI-TrNGRLGFEYNEGSKYWRSFTYGEDTMIGSKLAARGKAYEAYYTQ 440 Desulfurispiril...
WP_013459098 370 -YKGSGkqgmlgsfDSETGYSYWIGTQFPsl-iS-E-EGRWGIEFNHGSSFWRPLTYGEDTLIGSKIAARGDAYEVYFTE 445 Sulfuricurvum k...
WP_013326203 393 ----------lgstEAQNGYSEWVGVQYPsl-iS-E-EGRWGLEYNHGSKYWRSITYGEDTNIGSKLAARGDAYEAYFTE 459 Sulfurimonas au...
WP_012663627 381 GNpv--------yeGTHSGHSVWVGADMPg--fK-D-GDRFGLSYVKGSKYWRSFTYGEDTLAGSIAAVRGKAVDVYYNT 448 Nautilia profun...
BAF71004     332 ----FAgqmmmgspDDETGTSWWIGANLPvgegA-E-YGTFGAEYNHGSQYWRPFTYAEDTMIGSKVAARGDAWEAYYTY 405 Sulfurovum sp. ...
WP_013010954 509 MYQFMDmdrmlgskDSKTGTSVWVGVATPei-pL-T-GGKFGFEYNQGSKYWVSMTAAEDDLVGSKLAVRGKVYDVYYHQ 585 Denitrovibrio a...

Q8E9W9       514 DIN--PKMFIKLAGLYYDYEYTGSGTPV----GA----PQKI-DDVLAGSa----------------------------- 553 Shewanella onei...
Q7MSA6       446 PLIgkDTLTMDLRFTQIKYDYTGSNAFF----GYeg-mPLSI-DEAKAAYaa---------------------------- 491 Wolinella succi...
WP_012083203 450 ELIg-RTLTAQVRYTYIDYKYSGSQSFF----GEgg-nPMTM-NDIRGLQm----------------------------- 493 Nitratiruptor s...
WP_025346302 437 PIVg-KNLTAQLSYIYIDYDYTGSDTFF----GWtg-tPQDV-DTTTGA------------------------------- 478 Sulfurospirillu...
WP_013504803 441 PLVg-NTLSMQLRYTYIDYDYTGSNAFFgd-dGA----PQTIaDAAAAGAa----------------------------- 485 Desulfurispiril...
WP_013459098 446 PLVd-DILTFQLRYTYINYDYSGSNGFF----GSvtgtPMSM-DQAIGAG------------------------------ 489 Sulfuricurvum k...
WP_013326203 460 PLId-DILSLQIRYTYIDYKYAGSNGFF----GStsgnAMSI-NEAIAAG------------------------------ 503 Sulfurimonas au...
WP_012663627 449 EIV--PHLTAGLRYTYIKYDHAGSDGFF----GM-------M-AD--PDVa----------------------------- 483 Nautilia profun...
BAF71004     406 QIN--DALSLQARYTDISYDYTGSNGFFgnysGA----SIKI-DDIKAGAagfdqmaaagviqhqdpagiigdlmgaglt 478 Sulfurovum sp. ...
WP_013010954 586 PIVg-DRLFATIGYQHFDYEYTGSGSYL----GA----PKKI-EDATAFD------------------------------ 625 Denitrovibrio a...

Q8E9W9       554 -----------ySM--LPVVDKAFDVNASLTINF 574 Shewanella oneidensis
Q7MSA6       492 -----------gMG--SDVVEKASDIRVAFRYRY 512 Wolinella succinogenes
WP_012083203 494 ------------LGypVNAVDKAQDLRLYVRYRY 515 Nitratiruptor sp. SB155-2
WP_025346302 479 -------------------VKTAQNVRASLRYRY 493 Sulfurospirillum multivorans
WP_013504803 486 ------------MG--MDPVDSASDIRLSFRYRF 505 Desulfurispirillum indicum
WP_013459098 490 ------------YG--DNVVDKAQDIRAYLRYKF 509 Sulfuricurvum kujiense
WP_013326203 504 ------------NG--SKVVDKAQDIRFYLRYRY 523 Sulfurimonas autotrophica
WP_012663627 484 ------------DN--FSYVKKATDIRAYIRYKF 503 Nautilia profundicola
BAF71004     479 qaqaqgmlmakgMS--SQVVEKAQDFRIYLRYRF 510 Sulfurovum sp. NBC37-1
WP_013010954 626 ------------TM--MAVTDKVDKVYASFTYRY 645 Denitrovibrio acetiphilus
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