Conserved Protein Domain Family
Kelch_5

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pfam13854: Kelch_5 (this model, PSSM-Id:290565 is obsolete and has been replaced by 433528)
Kelch motif
The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that the ring canal kelch protein is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.
Statistics
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PSSM-Id: 290565
Aligned: 67 rows
Threshold Bit Score: 29.4711
Created: 29-Jun-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q4WVD1        460 PAPRFRHSAVkitleT-D--S-----ESVLVYGGKSS---DGSIFD-TWL---LW---QTHSN 504  Aspergillus fumigatus Af293
XP_002768082  109 PPSFAYHPTV-----VrVpdS-----SEALFIGAVKApqhKEEYAL-EVWldtVH---DKREH 157  Perkinsus marinus ATCC 50983
XP_002676247  805 PRSVYNVFIE-----I-I--D-----KTMYFFGGRVn---RVQSVG-DIH---VA---SLADW 844  Naegleria gruberi strain NEG-M
XP_002671279  763 PFPIYNGVVY-----V-L--D-----DSLYLLGGRAYp--SNQPTS-EIY---IA---SIFDM 803  Naegleria gruberi strain NEG-M
XP_002671279  708 PYPVASGMVA-----L-V--D-----EFLYIFGGLTLdrdEIVPTY-KVI---RA---NVSNL 750  Naegleria gruberi strain NEG-M
XP_003864878  666 PPPLHSAAAT-----A-L--Ss----DTVLVSGGVLL---GQDACNpHLW---QL---RLSTK 707  Leishmania donovani
XP_002676179  400 PVSIYSTHYL-----K-L--D-----EYVYFFGGFI----NDHLSN-AVY---RApysDVETG 441  Naegleria gruberi strain NEG-M
XP_002676251  518 PDSIHNSHFF-----K-H--N-----EEMYLFGGIV----NNNVSN-AIY---KC---PLYDL 556  Naegleria gruberi strain NEG-M
XP_002676169  513 PVSIYNSHFL-----K-A--D-----EYVYFFGGFI----NDEVSN-KIYrapIY---DVESG 554  Naegleria gruberi strain NEG-M
XP_001274463  460 PAPRFRHSAV-----K-L--SldsdsEVVLVYGGKSS---DGSIFD-NWL---MW---RKDGA 504  Aspergillus clavatus NRRL 1
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