Conserved Protein Domain Family
DUF4541
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pfam15074: DUF4541 (this model, PSSM-Id:291733 is obsolete and has been replaced by 405720)
Domain of unknown function (DUF4541)
This family of proteins is found in eukaryotes. Proteins in this family are typically between 100 and 163 amino acids in length. There is a conserved KLHRDDR sequence motif. There is a single completely conserved residue Y that may be functionally important. In humans, the gene is found in the chromosomal location, C5orf49.
Links
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Statistics
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PSSM-Id: 291733
Aligned: 27 rows
Threshold Bit Score: 86.1327
Created: 1-Jul-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
Download Cn3D
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q9DAR0        77 SYFSREGQT-G-IV----S----LYDCVFKRR---L-DYNQKLHRDDREHakNLGLHINEEEQERTVPVLMSSVYGKriN 142 house mouse
XP_003443825  32 SYFNNEPKV-S-DV----S----MYDRLNNHV---E-GYDMRLPRDDRKHwkGRGLDINKEERSRTVPVLSSSEYGRrpA 97  Nile tilapia
GAA56678      48 TYFNSPKKPdK-PS----C----VYDAVFSGH---E-ELNQKLHRCDRRHakLIGLHTYQEEATKTVPSLSSSEYGHrlD 114 Clonorchis sine...
XP_001637985  83 SYFNNGKQQ-T-RV----L----TYDRMFKIK---Q-GYCSKLHRDDRQH--TDAFDVHAEECEKAVPVLTSSQYGR--R 144 starlet sea ane...
XP_002612505  56 TVYNNNKEH-Q-EK----S----AYERLFNQE---S-DYNSKLHRDDRQH--TVGLNVHAEETSKAVPLRSSSQYGFllN 119 Florida lancelet
XP_003385783  59 SYFDNQKTH-K-RD----Y----DYDMTFCVN---E-GYNQKLKRDDMQH--TQGLNIRGEEENKPVPILSNSVYGK--G 120 Amphimedon quee...
EFN69319     182 TYFDNRKRE-G-RIadvgS----AYDRLHDVT---P--FDPSKPRCDRTKpsLIWAEIHEENKRHAVPMTANHWYSRpnR 250 Florida carpent...
XP_008198206  43 TYFDNPMKR-QhRS----A----EYDLFFAYTkvfP-LWDPRKPKDNCQYlrDIRENIYQQEKAKPVPVLTSLNYGLaaR 112 red flour beetle
CBY43677      64 YEFDTSTHS-R-KNid-nR----QYDRIFNAD---C-NYDPKLHRDDRSNakSRGLDVVNEETRRVTPLLSNAQYGG--R 130 Oikopleura dioica
XP_004990503  30 gFFGSPNKL-A-TK----TlsetMYDRQMHVP---EqDKSSKLHRDDRQs--RVGLDIHKEERERAFPVRSSSLYGa--R 96  Salpingoeca ros...

Q9DAR0       143 QPIEPLN-R-DYGHVSHVKTDFYRKN 166 house mouse
XP_003443825  98 PALYVPE-R-QYARVACIKSEIYMKN 121 Nile tilapia
GAA56678     115 NQFDPRN-R-SHARIMLVESEFFRRN 138 Clonorchis sinensis
XP_001637985 145 PPLETPQ-R-KHVRVATVKRDFYRYS 168 starlet sea anemone
XP_002612505 120 RPCDPPM-RgEYVRVAHVFKGFYRDR 144 Florida lancelet
XP_003385783 121 APLESMT-R-DYVRVAVVRRQFYRSS 144 Amphimedon queenslandica
EFN69319     251 IQIDYPD-M-RFARSSKTR-DFYSRN 273 Florida carpenter ant
XP_008198206 113 RLLDQPE-T-CYKRI-HATGDFKRRR 135 red flour beetle
CBY43677     131 PPLEIPD-G-KHRRVAVVKGEFFSNS 154 Oikopleura dioica
XP_004990503  97 APIDNLVhM-ANGRKKVVSQEFYSKE 121 Salpingoeca rosetta
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