Conserved Protein Domain Family
TMEM37
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pfam15108: TMEM37 (this model, PSSM-Id:291767 is obsolete and has been replaced by 434465)
Voltage-dependent calcium channel gamma-like subunit protein family
This family of transmembrane proteins, TMEM37, has a role in stabilizing the calcium channel in an inactivated (closed) state. It is a subunit of the L-type calcium channels. This family of proteins are found in eukaryotes. Proteins in this family are approximately 210 amino acids in length.
Links
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Statistics
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PSSM-Id: 291767
Aligned: 11 rows
Threshold Bit Score: 243.878
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q3ZCJ1         8 AQRLLGQRGPHr-sFFESFTRALITLCTSLAVVLSSISICDGEWLLAGDHLFGLWRFCTA-----------SNQTELHCL 75  cattle
Q6NUY2         9 GPVPRVKSSPL---FLDLFCRGLIILCTSVSVVLSSVAVCDGHWLLSGQHMFGLWYFCSVevpqgsvlgpqSFTASANCT 85  zebrafish
XP_001367802   8 AQKLLAQRRPPk-sFFESCIRTLIILCVAIAVVLSSVSICDGHWLRVKDQLFGLWHFCAL-----------TNNSELNCF 75  gray short-tail...
XP_005991126   8 TQGTLYGRRPRr-pFFDAFIRSLIILCTAIAVVLSSISICDGHWLFVNNRVFGLWHFCNV-----------GNDGQRECT 75  coelacanth
XP_006636427   8 agsvhfySKPKp-pFLEIFTRSLIILCTAFAIVLSSIAVCDGHWLLAEGKMFGLWHFCTL-----------EDKSLPNCT 75  spotted gar
XP_001234272   8 AQRLLAHRRPQk-aFFETFIRSLIILCVAIAVVLSSISVCDGRWLLARGELFGLWHFCAI-----------GNDSAPRCV 75  chicken
XP_002917621   8 AQRLLAQRRPQr-pFLESFIRALIIVCAALALVLSSISICDGHWLLAEDRLFGLWHFCTS-----------SNQTGTHCL 75  giant panda
XP_007612321   8 TQRLLGPKRPHr-sFFESFIRTLIIVCTALAVVLSSVSICDGHWLLVEDRLFGLWYFCTI-----------SNHSEPHCM 75  Chinese hamster
XP_002812459   8 AQRPLGQRQPHr-sFFESFIRTLIITCVALAVVLSSVSICDGHWLLAEDHLFGLWHFCTA-----------TNQSAPICF 75  Sumatran orangutan
XP_006169623  18 AQRLLGPRRPHrrsFFESFIRTLIILCAALAVVLSSVSICDGYWLLAGDRVFGLWHFCTT-----------TNQSEIHCL 86  Chinese tree shrew
XP_003133353   8 AQRLLAQRRPHq-sFFESFIRTLIILCASLAVILSSISICDGHWLLAEDRLFGLWQFCTT-----------SNQTAPHCV 75  pig

Q3ZCJ1        76 RDLSQTQVPWLASGLVVARIVATLAVVVAIFGLEFLIVSQVCEDSLAWRKWAMGSTLLLISFILSFGGLLSFLVLLRSQV 155 cattle
Q6NUY2        86 RRLEEAGVEGLDMGLAACRSVITLAVVSAIFGLELLVMSQASEGRDSSRRWTLGARLVLLAGVMAAGGVATFVLILGAFA 165 zebrafish
XP_001367802  76 TNLHLAQVDGLAVGMVLARSMGALAVVVAIFGLELLMVSQLCEDAHSRRKWAMGSIFILISFVFSSLGFLSFVILFKDQV 155 gray short-tail...
XP_005991126  76 TDLNMARVTGLQLWTAFSRSLASLAVVVAIFGLELLIISQVCEDAHSSRKWSLGSALVLASFALSFGGVVTFTLLLKDFV 155 coelacanth
XP_006636427  76 TDLGEAGVDSLPVGLVLCRSVVSFSVVAAIFGLELLVMSQVCEDQDSRKRWSVGSALVLLSFTLSASGLLGFVALLWSYA 155 spotted gar
XP_001234272  76 TDLRLARVEGLSVGMILIRSMVSSAVAVAIFGLELLMVSQVCEDASSRRKWSMGSVLILGSFLLSATGVLSFLILMKDHL 155 chicken
XP_002917621  76 RDLSRAQVPGLAVGMVLARSMGALAVVAAILGLELLMVSQVCEDLHSRSKWAVGSVVLLISFVLSSGGLLSFVILLWNHV 155 giant panda
XP_007612321  76 RDLSQAHMPGLAVGMGLARSVAALAVVAAIFGLELLMVSQVCEDVRSRRKWAIGSYLLLVAFILSSGGLLTFIILLKSQI 155 Chinese hamster
XP_002812459  76 RDLGQAHVPGLAVGMGLVRSVGALAVVAAIFGLEFLMVSQLCEDKHSRRKWVMGSILLLVSFILSSGGLLGFVILLRNQV 155 Sumatran orangutan
XP_006169623  87 RDFSGTGVPGLPMVLGLARSMGALAVVAAIFGLELLMVSQVCEDIHSRRKWAMGSILLLVSFFLSSGGLLCFVILLRSHI 166 Chinese tree shrew
XP_003133353  76 RDLSQAHVPELAWGMVLARSMATLAVVVAIFGLEFLMVSQVCEDLHSRHKWAMGSVLLLVSFVLSFGGLLSFLILLRNQV 155 pig

Q3ZCJ1       156 TLLGLTLMFWSDFTASFLLFLNGISGLHINSITH 189 cattle
Q6NUY2       166 SLLGFTLTFWCQFTATFLFFLNGMAARHIQNIKP 199 zebrafish
XP_001367802 156 TFTGFTLMFWCEFTSSFLFFLNGISGLHINSITH 189 gray short-tailed opossum
XP_005991126 156 SFTGFTLTYWCEFIASFLFFLNGLSGQHINGIiv 189 coelacanth
XP_006636427 156 SLLGFSLTFWCQFTAAFLFFLNGMSGHHIHSMvl 189 spotted gar
XP_001234272 156 TFTGFTLTYWCEFIAAFLFFLNGISGLHINSITQ 189 chicken
XP_002917621 156 TLTGFTLMFWCEFTASFLFFLNAISGLHINSITQ 189 giant panda
XP_007612321 156 TLMGFTLMFWCEFTASFLFFLNATSGLHINSLTQ 189 Chinese hamster
XP_002812459 156 TLIGFTLMFWCEFTASFLLFLNAISGLHINSITH 189 Sumatran orangutan
XP_006169623 167 TFMGFTLTFWCEFTASFLFFLNAISGLHINSITH 200 Chinese tree shrew
XP_003133353 156 RLIGFTLMFWSEFTASFLLFLNAISGLHINSLTH 189 pig
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