Conserved Protein Domain Family
Cadherin_tail
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pfam15974: Cadherin_tail (this model, PSSM-Id:292596 is obsolete and has been replaced by 435046)
Cadherin C-terminal cytoplasmic tail, catenin-binding region
Cadherin_tail is the cytoplasmic domain at the C-terminus of cadherin proteins. This domain binds p120 catenin, an action critical for the surface stability of cadherin-catenin cell-cell adhesion complexes.
Links
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Statistics
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PSSM-Id: 292596
Aligned: 7 rows
Threshold Bit Score: 112.015
Created: 2-Jul-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q7ZX86       809 QAQPNADWRFSQAAQkPGPSG------------------TQPTEE-----------AGVWPnnqfeterlqamiLASANE 859  African clawed...
Q6R0I3       846 PKHPNPDWRYSASLR-AGMQRvlciwr-------rqgsyVEDQEGlt-------ssGQQSP-------------VLLQPE 897  chicken
XP_012372968 552 PRQPNPDWRYSASLR-AGMHSsvhle---------eagiLRAGPGg---------pDQQWPtv---------ssATPEPE 603  degu
NP_001019345 806 QKPPSADWRFTQNQR-PGPSG------------------AAATPEva-------vgTGPWPnpptea-eqlqalMAAANE 858  zebrafish
NP_001103206 818 QKPPNTDWRFPPNQR-PGPSGqhrfhtlqqrwtpyeksrAGARPEeagagagviagTGPWPnp---------ptEAEQLQ 887  zebrafish
BAD52332      78 PKVPSSDWRYSASLR-AGMQSsvrme---------essvMQGAQGv---------lVQNWPtv----------sSAPDNE 128  zebrafish
ABL75839     809 PKAPNADWRYSASLRaAGVQSsvhme---------easvMQGAQGm---------lVQNWPtv---------ssAADGEG 861  torafugu

Q7ZX86       860 AAEGTSGLGGGtgTMGLSARYGPQF----TLQHVPDY--RQNVYIPGSTLT--------------------PTNGGGKRE 913  African clawed...
Q6R0I3       898 AGEVSPPVGAGvnSNSWTFKFGPSN----SKQGGPGEl-PDKFIIPGSPAIisirqeppn---sqidksdfITFGKKEET 969  chicken
XP_012372968 604 AGEVSPPVGAGvnSNSWTFKYGPGN----PKQSGPGEl-PDKFIIPGSPAIisirqeptn---sqidksdfITFGKKEET 675  degu
NP_001019345 859 VSEATNFLAPG--TMDLSTRYGPQF----TLQHVPDY--RQNVYIPGSTATltsnqqqpqqalpppqasaaIAVAQPEPP 930  zebrafish
NP_001103206 888 A------MMAAanASEATATLGPRY----NLQYGPDY--RQNVYIPGSTATltanpqqqv---lqqalpppQALPPTEVP 952  zebrafish
BAD52332     129 GGEVSPPVGAGvdSNSWHFRYGPGPg--gPPHLKPGEvpPEAFIIPGSPAIisirqgqd-----gddksdfITFGKKEEA 201  zebrafish
ABL75839     862 GGELSPPVGAGvnSNSWNFRYGAAQayypPQPLKPGEipPEAFIIPGSPAIisirhdag----pvddkgefISFGKKDEA 937  torafugu

Q7ZX86       914 ----------GKGNKKKSSKK 924  African clawed frog
Q6R0I3       970 ----------KKKKKKKKGNK 980  chicken
XP_012372968 676 kkkkkkkkgnKAQEKKEKGNs 696  degu
NP_001019345 931 ----------KAAQtpaskkk 941  zebrafish
NP_001103206 953 ----------KAAQtpaskkk 963  zebrafish
BAD52332     202 ----------KKLKKKKKKEK 212  zebrafish
ABL75839     938 ----------KKKKKKKKDKK 948  torafugu
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