3NR6,1BAI,1W5Y


Conserved Protein Domain Family
RVP
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pfam00077: RVP (this model, PSSM-Id:306563 is obsolete and has been replaced by 425454)
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Retroviral aspartyl protease
Single domain aspartyl proteases from retroviruses, retrotransposons, and badnaviruses (plant dsDNA viruses). These proteases are generally part of a larger polyprotein; usually pol, more rarely gag. Retroviral proteases appear to be homologous to a single domain of the two-domain eukaryotic aspartyl proteases such as pepsins, cathepsins, and renins (pfam00026).
Links
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Statistics
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PSSM-Id: 306563
Aligned: 12 rows
Threshold Bit Score: 98.1779
Created: 11-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3NR6_A         21 PEPRITLKVGGQ----------PVTFLVDTGAQHSVLTQNPGPLS-----DKSAWVQGATGGK-RYR-WTTDRKVHLATG 83   Xenotropic Mu...
A1Z651        546 PEPRITLKVGGQ----------PVTFLVDTGAQHSVLTQNPGPLS-----DKSAWVQGATGGK-RYR-WTTDRKVHLATG 608  Xenotropic Mu...
P03353        455 QQPILGVRISVMgqt-----pqPTQALLDTGADLTVIPQTLVPGPv---kLHDTLILGASGQT-NTQ-FKLLQTPLHIFL 524  Human T-lymph...
P19199       1195 YNGLYNVKVGIKpdnm---epyYINAIVDTGATACLIQISAIPENyyedaKVTVNFRSVLGIGtSTQ-MIKAGRILIGEQ 1270 Commelina yel...
P04585        495 QRPLVTIKIGGQ----------LKEALLDTGADDTVLEEMSLPGR-----WKPKMIGGIGGFI-KVR-QYDQILIEICGH 557  HIV-1 M:B_HXB2R
Q9IZT2        753 SRPMLHISLNGR----------RFLGLLDTGADKTCIAGRDWPANwp-ihQTESSLQGLGMAC-GVA-RSSQ-PLRWQHE 818  Mouse mammary...
P63120          8 NRPVCKAIIQGK----------QFEGLVDTGADVSIIALNQWPKNwp-kqKAVTGLVGIGTAS-EVY-QSTEILHCLGPD 74   human
Q9TTD4        144 ARPELELRINGK----------LFRGVLDTGADISVISDKYWPTTwp-kqMAISTLQGIGQTT-NPE-QSSSLLTWTDKD 210  sheep
YP_009109693   17 pEPRLTLSVGGH----------PTTFLVDTGAQHSVLTKANGPLS-----SRTSWVQGATGRK-MHK-WTNRRTVNLGQG 79   Baboon endoge...
P0C776        586 DRPLVRVILTNTgshpvkqrsvYITALLDSGADITIISEEDWPTDwpvmeAANPQIHGIGGGIpMRK-SRDMIEVGVINR 664  Rous sarcoma ...
1BAI_A          9 DRPLVRVILTNTgshpvkqrsvYITALLDTGADDTVISEEDWPTDwpvmeAANPQIHGIGGGI-PVRkSRDMIELGVINR 87   Rous sarcoma ...
1W5Y_A         18 QRPLVTIKIGGQ----------LKEALLDTGADDTVLEEMSLPGRw-----KPKMIGGIGGFI-KVR-QYDQILIEICGH 80   Human immunod...

3NR6_A         84 KVTH--SFLHVP---D-CPYP------LLGRDLLTKLKAQIH 113  Xenotropic MuLV-related virus VP62
A1Z651        609 KVTH--SFLHVP---D-CPYP------LLGRDLLTKLKAQIH 638  Xenotropic MuLV-related virus VP62
P03353        525 PFRR--SPVILS---S-CLLDthnkwtIIGRDALQQCQGLLY 560  Human T-lymphotropic virus 2
P19199       1271 YFRMpvTYVMNM---GlSPGIq----mIIGCSFIRSLEGGLR 1305 Commelina yellow mottle virus
P04585        558 KAIG--TVLVGP-----TPVN------IIGRNLLTQIGCTLN 586  HIV-1 M:B_HXB2R
Q9IZT2        819 DKSGiiHPFVIP---T-LPFT------LWGRDIMKEIKVRLm 850  Mouse mammary tumor virus (STRAIN C3H)
P63120         75 NQEStvQPMITS-----IPLN------LWGRDLLQQWGAEIT 105  human
Q9TTD4        211 GHTGqfKPYILP---Y-LPVN------LWGRDILSKMGVYLy 242  sheep
YP_009109693   80 MVTH--SFLVVP---E-CPYP------LLGRDLLTKLGAQIH 109  Baboon endogenous virus strain M7
P0C776        665 DGSLerPLLLFP---AvAMVRg----sILGRDCLQGLGLRLT 699  Rous sarcoma virus (strain Schmidt-Ruppin A)
1BAI_A         88 DGSLerPLLLFPlvaM-TPVN------ILGRDCLQGLGLRLT 122  Rous sarcoma virus
1W5Y_A         81 KAIGt--vLVGP---T--PVN------IIGRNLLTQIGCTLN 109  Human immunodeficiency virus
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