1MMP,3BA0,4AUO,2JSD,1BQQ


Conserved Protein Domain Family
Peptidase_M10

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pfam00413: Peptidase_M10 (this model, PSSM-Id:306839 is obsolete and has been replaced by 334067)
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Matrixin
The members of this family are enzymes that cleave peptides. These proteases require zinc for catalysis.
Statistics
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PSSM-Id: 306839
View PSSM: pfam00413
Aligned: 69 rows
Threshold Bit Score: 105.393
Threshold Setting Gi: 82100716
Created: 12-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1MMP_A   9 KW-TSK----VVTYRIVSYTRD--LPHITVDRLVSKALNMWGKEIP-LHFRKV-VWGT---ADIMIGFARGAHGD-SYPF 75  human
Q8AX63 120 AKkEPTtqgeTDACTIDGEDGE--FGAAEEPKDIIEAFGPTSAG----------KGWR---GDLMIEWGRQEESE-GTPF 183 Amur catfish
O04529 163 RWpRNRr---DLTYAFDPKNPL----TEEVKSVFSRAFGRWSDVTA-LNFTLSeSFST---SDITIGFYTGDHGD-GEPF 230 thale cress
Q5XF51 167 RWpRNRr---DLTYAFDPRNAL----TEEVKSVFSRAFTRWEEVTP-LTFTRVeRFST---SDISIGFYSGEHGD-GEPF 234 thale cress
Q9ZR44 128 KW-FPKgt-kELTYGFLPES----KISIDKVNVFRNAFTRWSQTTRvLKFSEAtSYDD---ADIKIGFYNISYNS-KEVI 197 barrel medic
P29136 142 RWqAGTt---QLTYAFSPEPRL----DDTFKSAIARAFSKWTPVVN-IAFQETtSYET---ANIKILFASKNHGD-PYPF 209 soybean
Q9LEL9 168 KWpSSKl---HLSYGFLPNYPI------DAIKPVSRAFSKWSLNTH-FKFSHVaDYRK---ADIKISFERGEHGD-NAPF 233 cucumber
Q8K3F2 169 AF-SKK----TLTWRLVGDAYSsqLSGDEQRYIFRLAFRMWSEVTP-LDFRED-RTAPgtmVDIKLGFGRGRHLGcPRVF 241 house mouse
O93470 205 VF-TKK----LLKWRMIGEGYSnqLSINEQRYVFRLAFRMWSEVMP-LDFEED-NTSPlsqIDIKLGFGRGRHLGcSRAF 277 African clawed frog
Q23227 117 LW-TKK----SLTYKVVNTPNT--LSQAQIRSAAHEAFEQWTRASG-FKFVET-TGAT---PDITITFYDVPQSN-LR-- 181 Caenorhabditis elegans
1MMP_A  76 DGPGNTLAHAFAPGTGLGG-DAHFDEDERWTD--GS-------------------------------------------- 108 human
Q8AX63 184 EQKDGILGHEFP-GSGTGS-DSHFDDDEQWTL--GEaivlkikegniagegckfpfaiqgieyqsctegrdegwlecati 259 Amur catfish
O04529 231 DGVLGTLAHAFSP---PSG-KFHLDADENWVVsgDLdsf----------------------------------------- 265 thale cress
Q5XF51 235 DGPMRTLAHAFSP---PTG-HFHLDGEENWIVsgEGgdgf---------------------------------------- 270 thale cress
Q9ZR44 198 D----VVVSDFFI--NLRSfTIRLEASKVWD------------------------------------------------- 222 barrel medic
P29136 210 DGPGGILGHAFAP---TDG-RCHFDADEYWVAsgDVtks----------------------------------------- 244 soybean
Q9LEL9 234 DGVGGVLAHAYAP---TDG-RLHFDGDDAWSV--GAi------------------------------------------- 264 cucumber
Q8K3F2 242 DGSGQEFAHAWRL-----G-EIHFDDDEHFTP--LSs------------------------------------------- 270 house mouse
O93470 278 DGSGQEFAHAWFL-----G-DIHFDDDEHFTA--PSs------------------------------------------- 306 African clawed frog
Q23227 182 -----IAGSASKP---VNS-HIILDKNQEWAY--KSq------------------------------------------- 207 Caenorhabditis elegans
1MMP_A     -------------------------------------------------------------------------------- human
Q8AX63 260 ydfdengkysecpyeglftqginseggpcklpfifqaenydgcitsgrddgyrecaitenwdndksygfcpeiaasllgn 339 Amur catfish
O04529     -------------------------------------------------------------------------------- thale cress
Q5XF51     -------------------------------------------------------------------------------- thale cress
Q9ZR44     -------------------------------------------------------------------------------- barrel medic
P29136     -------------------------------------------------------------------------------- soybean
Q9LEL9     -------------------------------------------------------------------------------- cucumber
Q8K3F2     -------------------------------------------------------------------------------- house mouse
O93470     -------------------------------------------------------------------------------- African clawed frog
Q23227     -------------------------------------------------------------------------------- Caenorhabditis elegans
1MMP_A 109 --------------------------------------------SLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGn 144 human
Q8AX63 340 aeggpciiavellqqetessvqdgkeggkmcaiikeffddawglPQEASAFLVEAHEYAHLQGLAH--DPG--LTATYE- 414 Amur catfish
O04529 266 -----------------------------------------lsvTAAVDLESVAVHEIGHLLGLGHSSVEESIMYPTITt 304 thale cress
Q5XF51 271 -----------------------------------------isvSEAVDLESVAVHEIGHLLGLGHSSVEGSIMYPTIRt 309 thale cress
Q9ZR44 223 -------------------------------------------------LETVAMHQIGHLLGLDHSSDVESIMYPTIVp 253 barrel medic
P29136 245 ------------------------------------------pvTSAFDLESVAVHEIGHLLGLGHSSDLRAIMYPSIPp 282 soybean
Q9LEL9 265 --------------------------------------------SGYFDVETVALHEIGHILGLQHSTIEEAIMFPSIP- 299 cucumber
Q8K3F2 271 --------------------------------------------DTGISLLKVAVHEIGHVLGLPHTYRVGSIMQPNYIp 306 house mouse
O93470 307 --------------------------------------------EHGISLLKVAAHEIGHVLGLSHIHRVGSIMQPNYIp 342 African clawed frog
Q23227 208 -------------------------------------------aPMGISLYHTLLHEIGHILGLPHTFYRGSIMHPIFKp 244 Caenorhabditis elegans
1MMP_A 145 --gDpqNF-KLSQDDIKGIQKLYG 165 human
Q8AX63 415 ---MapEN-RIDNDDIKGIQELYA 434 Amur catfish
O04529 305 ---GkrKV-DLTNDDVEGIQYLYG 324 thale cress
Q5XF51 310 ---GrrKV-DLTTDDVEGVQYLYG 329 thale cress
Q9ZR44 254 --lHqkKV-QITVSDNQAIQQLYT 274 barrel medic
P29136 283 ---RtrKV-NLAQDDIDGIRKLYG 302 soybean
Q9LEL9 300 ---EgvTK-GLHGDDIAGIKALYR 319 cucumber
Q8K3F2 307 ---QepAF-ELDWADRKAIQRLYG 326 house mouse
O93470 343 ---QdsGF-ELDLSDRRAIQNLYG 362 African clawed frog
Q23227 245 vllPhgTVdTVPNVDRLAIRKIYG 268 Caenorhabditis elegans
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