2OWA,2OLM,3MDB


Conserved Protein Domain Family
ArfGap
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pfam01412: ArfGap (this model, PSSM-Id:307528 is obsolete and has been replaced by 460200)
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Putative GTPase activating protein for Arf
Putative zinc fingers with GTPase activating proteins (GAPs) towards the small GTPase, Arf. The GAP of ARD1 stimulates GTPase hydrolysis for ARD1 but not ARFs.
Links
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Statistics
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PSSM-Id: 307528
Aligned: 126 rows
Threshold Bit Score: 104.249
Created: 15-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2OWA_B         24 DNFFQIVRN--R-PENRTCFDC---ESRNP-TWLSLS-FAVFICLNCSSDHRKMGVHISFVRSSDLDKFTPIQLVRMDIg 95   Cryptosporidi...
Q54DK4         10 YGLLRSLFQ--D-PNNQCCAEC---NSANV-PYVCIK-LGVFICPTCAHFLSTLG---FKVRPIMGSSFSEEDISRLQSi 78   Dictyostelium...
Q86H99          5 DTILWRLRE--L-EENSKCADC---TDSFP-RYMNTT-YGTFVCSVCGAIHRELG---NRVKSISSDKFTQQDIERLEKv 73   Dictyostelium...
Q4Q1A4         12 KEVLRKLSQ--N-GGNKNCFDC---GMRGP-LYVVSD-FGILVCSGCSAVHRSFQ---HKVKGITMSEFTDDEIARFSVs 80   Leishmania major
Q4DJC3         62 RDEVRKLSQ--K-CGNRFCIDC---GIRGP-LYVVTN-FRVFVCSTCAALHRSLQ---HKVKGISMTEFTDEEVACLNVg 130  Trypanosoma c...
Q383Y2          5 RDEVRKLSQ--K-DGNRFCMNC---RMRGP-VYVVLD-FGTFVCSACASLHRNKQ---HKVKGITMTEFTDEEVARLKVc 73   Trypanosoma b...
Q4D8K1        247 QSPLYALCIadR-PSNQICADC---GEKWP-TWAVLGpFGCFVCIHCVGVHRQLRPHCC--REVQLDNWDAAEIDFMAKr 319  Trypanosoma c...
XP_001417000    6 EQALTALAR--E-PGNKTCFSCvgpGSLAP-RSVCVP-FGIFVCTRCSGIFRDFN---FRIKSISASTFSGDEVEMLRRk 77   Ostreococcus ...
XP_001388247   11 IERLRSFQK--ScIENRKCANC---NEIGP-NYVCIN-FGTFVCSVCSGIHREFN---HKVKGISLSKWKFDEIRLICSl 80   Cryptosporidi...
XP_001705811   10 KNAIDALRR--K-PENKQCADC----KSLSvPYINLT-CGTFVCARCAGIHREFD---HRVKSVSNSVFKLDEIQALG-- 76   Giardia lambl...

2OWA_B         96 GNGRARNYFKQVl-----------gVNFSPKTKEYASSIcGRQYKQILDSEIS 137  Cryptosporidium parvum Iowa II
Q54DK4         79 GNLVSKQFWLARwtpmd----ivmpP---PEDPNLESFL-RLKYIEKRWTSSL 123  Dictyostelium discoideum
Q86H99         74 GNKMADEIWLSKwsqqq----yplpFP--SDEKRVRDFI-KMKYIEKKWIKEG 119  Dictyostelium discoideum
Q4Q1A4         81 GNDRARKVWLSTfhd-------qlpRS--GNVMALKDHV-HVVFEERRFWSAQ 123  Leishmania major
Q4DJC3        131 GNDRAARVWLASyen-------nkpPH--GSDIAVRDFI-VNAFENMAYVNRE 173  Trypanosoma cruzi
Q383Y2         74 GNDRAESVWLHGfkg-------erpPV--GNDFALQQFF-SRVYVAKEFASSA 116  Trypanosoma brucei
Q4D8K1        320 GNDVVNDELEYAgfflgsgdavykpVGSSSRREVREEYI-TLKYEGTF-TRER 370  Trypanosoma cruzi
XP_001417000   78 GNEAARRTFLARwnp-------aepLPQSGNTVRGKVWI-KAVFVDKLYYDDA 122  Ostreococcus lucimarinus CCE9901
XP_001388247   81 GNKKDFLTFLGNrdfn-----slgpPPNSNNHLILKEFI-RNKYINRIWINQS 127  Cryptosporidium parvum Iowa II
XP_001705811   77 GNDLDKRTYLPYwseqv----fklpEPGSEDNGRVRDFI-RMKYVEKRFCHEQ 124  Giardia lamblia ATCC 50803
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