Conserved Protein Domain Family
Na_trans_assoc
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pfam06512: Na_trans_assoc (this model, PSSM-Id:310839 is obsolete and has been replaced by 461936)
Sodium ion transport-associated
Members of this family contain a region found exclusively in eukaryotic sodium channels or their subunits, many of which are voltage-gated. Members very often also contain between one and four copies of pfam00520 and, less often, one copy of pfam00612.
Links
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Statistics
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PSSM-Id: 310839
Aligned: 67 rows
Threshold Bit Score: 90.464
Created: 21-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
P15390        810 DGEMNNLQIAIGRIKWGIGFAKTFLLGLLrgkilspkeiilslgepggagenaeestpedekkepppEDkEL-KDNHILN 888  Norway rat
XP_318122    1020 DNETNKIAEAFNRISRFSNWIKMNLANAL--------------------------------------KFvKNkLTSQIAS 1061 Anopheles gam...
XP_017101604 1046 DNDTNKIAEAFNRIGRFKSWVKRNIADCF--------------------------------------KLiRNkLTNQISD 1087 Drosophila bi...
ABP96886      480 DQDTNKIAEAFNRISRFIDWIKRNVADFL--------------------------------------KLlKNkLTNQIAI 521  domestic silk...
XP_011266375 1044 DNDTNKIAEAIDRIARFINWIKRNILNIA--------------------------------------KLmRAkFTNQISD 1085 Florida carpe...
XP_016836968 1021 DNDTNKITEAIDRISRFIAWTKRNILNLL--------------------------------------KMlRAkFTNQISD 1062 jewel wasp
EFA11577     1022 DNDTNKIAEAFDRIGRFIRWIKGNVLHIA--------------------------------------KLvRFkLTNQISD 1063 red flour beetle
KYB29592      991 DNDTNKIAEAFERIARFIRWIKGSVLDMV--------------------------------------KIvRFkLTNQISD 1032 red flour beetle
XP_002427248  967 DNDTNKIAEAFNRISRFNAWVKRSILNFL--------------------------------------KMlRAkISNQIGD 1008 human body louse
EFX81393     1003 DNDTNKLTEAFNRISRFKRWVRRSFSNGF--------------------------------------RMiRSkLTNQISD 1044 common water ...

P15390        889 HvgLTDGPRSSIE--------------LDHLN--------------FINN--PYLTIQvpIA------------------ 920  Norway rat
XP_318122    1062 V--QPTGkgvcpc--------issehgENELEltpddiladgllkkGIKEh-NQLEVA--IGdgmeftihgdlknkakk- 1127 Anopheles gam...
XP_017101604 1088 Qpse---------------------hgDNELElghdeiladglikkGIKEq-TQLEVA--IGdgmeftihgdmknskpk- 1142 Drosophila bi...
ABP96886      522 H--APer-------------------vDNELElgtdld--davlykDKKLk-DQVEVA--IGdgmeftipgdnkykk--- 572  domestic silk...
XP_011266375 1086 Q--APGEGPSNSWkedgidrdgdldlaDGELDayr--------dkkSAKEl-NQLEVA--IGegmeftihgdlknklk-- 1150 Florida carpe...
XP_016836968 1063 Q--APdgidrd----------mnmdlaEGELDayr--------dkkSVKElnNQFEVA--IGdgmeftihgdlknkmrt- 1119 jewel wasp
EFA11577     1064 Qpsd--------------------vrcDGGLDisgdeiladgiikkSPK---DRLEVT--IGtgmdltvhgdpkrg---- 1114 red flour beetle
KYB29592     1033 Qpsd---------------------erECALEisedeilanglmkkNPK---DRVEVTigIGtgmdltvhgdskanlk-- 1086 red flour beetle
XP_002427248 1009 HtgLPdgr-----------------drDTDLElgdeilv-dgmvfrDKKNskDQLEVA--IGdgmeftihgdfkeklrrs 1068 human body louse
EFX81393     1045 Qrapgelplfqigpfyfqcg--------------lfvfnfrasgmpaalhirRHIEIVvkIAasclflicdesmsklk-- 1108 common water ...

P15390        921 ------------------SEE-SDLEmp-----tEE---------ETDAFSEP--------------------------- 940  Norway rat
XP_318122    1128 -nkqimnnskvignsisnHQD-NKLD--------HElnhrgvslqDDDTASIKsygshknrpfkd---eshkgsaetmeg 1194 Anopheles gam...
XP_017101604 1143 --kskylnnatmignsinHQD-NRLE--------HElnhrglslqDDDTASINsygshknrpfkd---eshkgsaetmeg 1208 Drosophila bi...
ABP96886      573 ----gkilmnniyrithyHRD-NRLD--------CElnhhgypiqDDDTISQKsygshkirsfkd---eshkgsadtidg 636  domestic silk...
XP_011266375 1151 --nklcmnntkviansinHHD-YRLD--------NDyin----qnEDDTISNKsygshknrafkd---eshkgsmdslng 1212 Florida carpe...
XP_016836968 1120 --slclnntkalvnsinhHRD-FRLD--------HDymn----hnEDDTISNKsygshknrsfkd---eshkgsldsldg 1181 jewel wasp
EFA11577     1115 ----------knninksktignsiLEh-------GMyig----hlDEDEISNKsygshknrfkee---shkgsvdmlddh 1170 red flour beetle
KYB29592     1087 --------rdknslsksktignsiLDh-------SDfis----hlDDDEISNNsygshtyrfkdeshkgsadvledneeq 1147 red flour beetle
XP_002427248 1069 kmalnnknnvignsyaglNSD-NRFE--------SDyit----hnEEDTYSNIsygshrkriykd---eshkgsidtfee 1132 human body louse
EFX81393     1109 --nkkganntsavcpnstKKRpDELVldidcrknPK---------DDDTISYQsygshchritrd---eshkgslrvdyy 1174 common water ...

P15390        941 EDIKKplqplydgNSSVCSTADykppeEDPEEQAEENPEGEQ---------------------PEECFTEACVKRCPCLY 999  Norway rat
XP_318122    1195 EEKRD--------ASKEDLGID-----EELDDEGEGDEGPLDgeliihae-----edeviedsPADCCPDNCYKKFPVLA 1256 Anopheles gam...
XP_017101604 1209 EEKRD--------ASKEDLGLD-----EELDEEGECEEGPLDgdiiihah-----dedildeyPADCCPDSYYKKFPILA 1270 Drosophila bi...
ABP96886      637 EEKKD--------ASKEELGLE-----EELIEEDE--EGKLDgtlgktdikv-gadedvvddtPADCCPEQCYQKFPFLA 700  domestic silk...
XP_011266375 1213 EEKKD--------ASKEDLEQEg----EDLEDEGEEGEE-VDidiiqaee------dpiqdnyPSDCCPENCYKKFPFLA 1273 Florida carpe...
XP_016836968 1182 EEKKD--------ASKEDLEDDlddegEDEDEEEEEVEE-IPcriikqde------eldgensPSDCCPDNCYQRFPFLA 1246 jewel wasp
EFA11577     1171 EEKRD--------ASKEELGIGe----EETEDDRFDLEKPLTdivivgna-----ddiiiddyAADCFPDSCYKKFPFLA 1233 red flour beetle
KYB29592     1148 EEKRD--------ASKEELGIA-----EDTEEEGCECKEVLNedlvdant------ediideySADCCPESCYKKFPFLA 1208 red flour beetle
XP_002427248 1133 DEKGD--------MSKEE---------DEEMDEEEEGESIPEidviidanm----edvmlqdyPSDCCPDHCYKRFPFLA 1191 human body louse
EFX81393     1175 DEKRN--------ASKE----DldgfpEEARPAEVEGEDDGLaaeaavvkiahrvdsdedpqyPDACFPDHWYEKIPIIK 1242 common water ...

P15390       1000 VDISQGRGKMWWTLRRACF 1018 Norway rat
XP_318122    1257 GDDDAPFWQGWGNLRLKTF 1275 Anopheles gambiae str. PEST
XP_017101604 1271 GDEDSPFWQGWGNLRLKTF 1289 Drosophila bipectinata
ABP96886      701 GDDDSPFWQGWGTLRLKTF 719  domestic silkworm
XP_011266375 1274 GDDDAPFWQGWANLRLKTF 1292 Florida carpenter ant
XP_016836968 1247 GDDDAPFWQGWATLRLKTF 1265 jewel wasp
EFA11577     1234 GDEDSPFWQGWGNLRSKTY 1252 red flour beetle
KYB29592     1209 GDEDSPFWQGWANLRYKTF 1227 red flour beetle
XP_002427248 1192 GDDDAPFWQGWSNLRLKTF 1210 human body louse
EFX81393     1243 GNDDSPFWQGWAMLRLKTF 1261 common water flea
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