1TBR,1Z7K,4E0S


Conserved Protein Domain Family
Kazal_2

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pfam07648: Kazal_2 (this model, PSSM-Id:311539 is obsolete and has been replaced by 400135)
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Kazal-type serine protease inhibitor domain
Usually indicative of serine protease inhibitors. However, kazal-like domains are also seen in the extracellular part of agrins, which are not known to be protease inhibitors. Kazal domains often occur in tandem arrays. Small alpha+beta fold containing three disulphides.
Statistics
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PSSM-Id: 311539
Aligned: 50 rows
Threshold Bit Score: 32.2232
Created: 21-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1TBR_R   60 CDGDEYK-PVCGSDDITYDNNCRLECASISS----SPGVELKHEGPC 101  Rhodnius prolixus
Q08629  139 CPVAQSA-MVCGSDGHSYTSKCKLEFHACST----GKSLATLCDGPC 180  human
Q9D236   87 CRCRWTH-TVCGTDGHTYADVCALQAASRRAlqvsGTPVRQLQKGAC 132  house mouse
P83105  108 CPTLGGA--VCGSDRRTYPSMCALRAENRAArrlgKVPAVPVQWGNC 152  human
1Z7K_B   22 CNKALN--PVCGTDGVTYDNECVLCAHNLEQ----GTSVGKKHDGEC 62   turkey
P10184  307 CPFILQE--VCGTDGVTYSNDCSLCAHNIEL----GTSVAKKHDGRC 347  chicken
Q62356   56 CKPHKR--PVCGSNGKTYLNHCELHRDACLT----GSKIQVDYDGHC 96   house mouse
P25304   97 CPATVA--PVCGSDASTYSNECELQRAQCNQ----QRRIRLLRQGPC 137  Norway rat
Q9EQC7  123 CEGLPAGfQVCGSDGATYRDECELRTARCRG----HPDLRVMYRGRC 165  house mouse
P10669  122 CSNITWKgPVCGLDGKTYRNECALLKARCKE----QPELEVQYQGKC 164  pig
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