Conserved Protein Domain Family
Axin_b-cat_bind
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pfam08833: Axin_b-cat_bind (this model, PSSM-Id:312391 is obsolete and has been replaced by 462616)
Axin beta-catenin binding domain
This domain is found on the scaffolding protein Axin which is a component of the beta-catenin destruction complex. It competes with the tumor suppressor adenomatous polyposis coli protein (APC) for binding to beta-catenin.
Links
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Statistics
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PSSM-Id: 312391
Aligned: 8 rows
Threshold Bit Score: 45.2689
Created: 26-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q7PYV4        452 DDNDQDILDQHVSRV-WS---DLTPSRSPGTMspcppnmigSRSRR---HELASFGG 501  Anopheles gambiae str. PEST
Q17FL7        459 DDSDQDILDKHVSRV-WS---DLTPSRSPGTMspc---pniSRARR---HEVGGFGG 505  yellow fever mosquito
NP_001079086  383 EDDPQSILDDHVSRV-LKtpaNLSPRSQSPFV---------QRKGK---FQPAFSKG 426  African clawed frog
KRX87493      711 pEDAEAILDDYYNRVgWKdspKQSPMRSPGFA---------FGSRK---KSPGSKSP 755  Trichinella pseudospiralis
XP_015026051  441 EDNDQDILDQHVSRV-WK---DQTPHRSPGTMspcppipsrRRTAT---HDSGMVSD 490  Drosophila virilis
CDS34199      694 gDNAQAILEDHCSRI-WDtsaDRTPTSSSGSG---------G-NGT---HLQQVSSD 736  Hymenolepis microstoma
XP_011188089  483 EDNDQDILDQHVSRV-WK---DQTPHRSPGTMspcp-plptRR--RtitHDSGMLSD 532  melon fly
XP_011611147  507 DDDPESILDEHVQRV-MKtpgCQSPGATNSTL---------GGGGR---HSPPKSSR 550  torafugu
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