1OMX


Conserved Protein Domain Family
Glyco_transf_64
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pfam09258: Glyco_transf_64 (this model, PSSM-Id:312681 is obsolete and has been replaced by 430488)
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Glycosyl transferase family 64 domain
Members of this family catalyze the transfer reaction of N-acetylglucosamine and N-acetylgalactosamine from the respective UDP-sugars to the non-reducing end of [glucuronic acid]beta 1-3[galactose]beta 1-O-naphthalenemethanol, an acceptor substrate analog of the natural common linker of various glycosylaminoglycans. They are also required for the biosynthesis of heparan-sulphate.
Links
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Statistics
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PSSM-Id: 312681
Aligned: 23 rows
Threshold Bit Score: 256.441
Created: 26-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1OMX_A        30 FTLIMQT--YNRTDLLLRLLNHYQAVPSLHKVIVVWNNvgEKGPEEL-----------WNSLGPHpIPVIFKPQTANKMR 96  house mouse
Q28F88        60 FTLIMQT--YNRTDLLLKMLNHYQAMPGLSHVIVVWNNv-GQDTPQEl----------WESFGPHpVPVTFKKQKVNLMR 126 tropical clawed...
Q3TSR0        53 FTLIMQT--YNRTDLLLRLLNHYQAVPSLHKVIVVWNNv-GEKGPEEl----------WNSLGPHpIPVIFKPQTANKMR 119 house mouse
Q9LY62        74 YTLLMNT--WKRYDLLKKSVSHYASCSRLDSIHIVWSE--PNPPSESlkeylhnvlkkKTRDGHE-VELRFDINKEDSLN 148 thale cress
Q5Z8V4        87 YAVVINT--WKRYDLLRRSVAHYSGCGGVDAVHVVWSE--PEEPTEElrg-----svlNCSDGGG-AGVRFVINAEDSLN 156 Japanese rice
Q9C975        48 ITVLINGysEYRIPLLQTIVASYSSSSIVSSILVLWGN--PSTPDQLldql----yqnLTQYSPGsASISLIQQSSSSLN 121 thale cress
Q84WB7       518 FTLATMTy-DARLWNLKMYVKRYSRCPSVKEIVVIWNK---GPPPDL-----------SELDSA--VPVRIRVQKQNSLN 580 thale cress
XP_015650243  49 LTVLLSGysERRLPLLRAIAGAYAAHPLVLAVVVLWSN--PSTPDSL--------------LSSFpPAVTLHRTASASLN 112 Japanese rice
XP_016335161 113 FTAVVLT--YDRIESLFRVITEISKVPSLAKLLVVWNNq-NKSPPEE-----------SLWPKVT-VPLKVVRTKENKLS 177 Sinocyclocheilu...
XP_002280907  45 ITVLMNGysESRIPLLRSIAATYAASPPVAAVVILWGN--PSTPTRTlael----shnFTIAYTGaAPISLVRQASDSLN 118 wine grape

1OMX_A        97 NRLQVFPEVETNAVLMVDDD-TLISAQDLVFAFSIWQ--QFPDQIIGFVPRKHV-ST---SSGIYSYGGfelqtpgpgNG 169 house mouse
Q28F88       127 NRLQSFPEIQTQAVLMMDDD-TLVSAYDISFAFSIWQ--QFPDRIVGFVPRKHV-SS---PSGIYSYGSfelkaphteTG 199 tropical clawed...
Q3TSR0       120 NRLQVFPEVETNAVLMVDDD-TLISAQDLVFAFSIWQ--QFPDQIIGFVPRKHV-ST---SSGIYSYGGfelqtpgpgNG 192 house mouse
Q9LY62       149 NRFKEIKDLKTDAVFSIDDD-IIFPCHTVDFAFNVWE--SAPDTMVGFVPRVHWpEKsndKANYYTYSGwws----vwWS 221 thale cress
Q5Z8V4       157 NRFRPIQGLTTDAVFSVDDD-LIVPCSTLRFAFAVWQ--SAPSAMVGFVPRMHWlADpgsNAKEYRYGSwws----vwWT 229 Japanese rice
Q9C975       122 ARFLPRSSVDTRAVLICDDD-VEIDQRSLEFAFSVWK--SNPDRLVGTFVRSHG-FDl--QGKEWIYTV---------HP 186 thale cress
Q84WB7       581 NRFEIDPLIKTRAVLELDDD-IMMPCDDIEKGFRVWR--EHPERLVGFYPRF--------VDQTMTYSAekf----arSH 645 thale cress
XP_015650243 113 SRFLPHPSIRTAAVAVADDD-VLPDAAALSFAFAAWQqrARPGTLVGFFPRSHH-LDl--ARGRWAYGAaa------rQQ 182 Japanese rice
XP_016335161 178 NRFFPFDEIETEAVLAIDDDiIMLTSDELQFGYEVWR--EFPDRLVGYPGRLHL-WDh--EMGKWKYESe--------WT 244 Sinocyclocheilu...
XP_002280907 119 ARFLPRPFITTRGVIICDDD-VEVDPKSIEFAFRVWA--ANPHRLIGLFARAHD-LDl--SRREWIYTV---------HP 183 wine grape

1OMX_A       170 DQYSMVLIGASFFNSKY-LELFQ---K-QPAAVHALIDETQNCDDIAMNFLVTRHTGKPSgi-fVKPI------NMVNLE 237 house mouse
Q28F88       200 DMYSMILIGAAFFHSDY-LRLFE---Q-LPASVHNMIDQTQNCDDIAMNFMVANHLGKASgv-lVKPT------DMRNLE 267 tropical clawed...
Q3TSR0       193 DQYSMVLIGASFFNSKY-LELFQ---K-QPAAVHALIDETQNCDDIAMNFLVTRHTGKPSgi-fVKPI------NMVNLE 260 house mouse
Q9LY62       222 GTYSMVLSKAAFFHKKY-LSLYT---NsMPASIREFTTKNRNCEDIAMSFLIANATNAPA----IWVK------------ 281 thale cress
Q5Z8V4       230 GTYSMVLSKASFFHRQY-LDLYT---IrMLPSIRDYVNENRNCEDIAMSFLVANVTGSPP----IWVQgghtevPFRDVT 301 Japanese rice
Q9C975       187 DKYSIVLTKFMMMKQDY-LFEYSckgGvEMEEMRMIVDQMRNCEDILMNFVAADRLRAGPi--mVGAE------RVRDWG 257 thale cress
Q84WB7       646 KGYNMILTGAAFMDVRFaFDMYQ---SdKAKLGRVFVDEQFNCEDILLNFLYANASGSGKaveyVRPS-------LVTID 715 thale cress
XP_015650243 183 ARYSMVLTKLLVLGAGL-LREYSc--SpELAAARAVVDRERNCEDILMNFVAAEESGEGPv--lVEAG------SIRDWG 251 Japanese rice
XP_016335161 245 NEVSMVLTGAAFYHKYF-NYLYT---YkMPGDIKNWVDAHMNCEDIAMNFLVANITGKAP----IKVT------PRKKFK 310 Sinocyclocheilu...
XP_002280907 184 DKYSIVLTKFMVLKTEY-LYKYScegGaRMMEARKAVDMAQNCEDILMNFVVAEEGNAGPm--lVGAE------KVRDWG 254 wine grape

1OMX_A       238 KETNg--------------YSGMWHRAE--HFLQRSYCINKLVNIYDGMPLKYSNIMI--S 280 house mouse
Q28F88       268 KEAGs-------------gYTGMWHRAE--HLLQRSFCLNKLAEIYSTMPLKYSSIMI--S 311 tropical clawed frog
Q3TSR0       261 KETNg--------------YSGMWHRAE--HFLQRSYCINKLVNIYDGMPLKYSNIMI--S 303 house mouse
Q9LY62       282 -GKIye-----------igSTGISSIGG--HTEKRTHCVNRFVAEFGKMPLVYTSMKAvdS 328 thale cress
Q5Z8V4       302 AGRIfe-----------igSSGISSLKG--HDLQRSKCLNTFSAMYGHMPLVATTVKAvdS 349 Japanese rice
Q9C975       258 DARNeeve-------ervrDVGLSSRRVe-HRKRRGNCIREFHRVMGKMPLMYSYGKVv-N 309 thale cress
Q84WB7       716 TSKFs--------------gVAISGNTNq-HYRKRSKCLRRFSDLYG--SLVDRRWEFggR 759 thale cress
XP_015650243 252 DPRNddadagagaggeemkAVGLSSTGGaaHWEKRGDCITEFHRLLGRMPLRYSYGKVvaa 312 Japanese rice
XP_016335161 311 CPECt-------------aIDGLSLDQT--HMVERSECINKFASVFGTMPLKVVEHRA--D 354 Sinocyclocheilus anshuiensis
XP_002280907 255 DGRNdeglg------lkerEVGLSSRRGe-HRKRRGGCIGDFHRILRRMPLRYGYGKVv-N 307 wine grape
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