Conserved Protein Domain Family
PD-C2-AF1
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pfam09310: PD-C2-AF1 (this model, PSSM-Id:312716 is obsolete and has been replaced by 430516)
POU domain, class 2, associating factor 1
Members of this family are transcriptional coactivators that specifically associate with either OCT1 or OCT2, through recognition of their POU domains. They are essential for the response of B-cells to antigens and required for the formation of germinal centers.
Links
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Statistics
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PSSM-Id: 312716
Aligned: 5 rows
Threshold Bit Score: 384.266
Created: 26-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q90ZH6         7 SASEQQP---QPRPYQGVRVKEPVKELLKRKRGNV--HNATAAAATTvvlpHQPLPSYSPMGQ--------PCIDVDAAA 73  chicken
XP_002932979   8 NSEQQKNs--PARPYLGVRVKEPVKELLKRKRGNC--SNGNTMTPTV----PSSYQTYPTCTPivsnltdlPYVDMDIPT 79  western clawed ...
XP_008119288   7 SAPEPPPpqpSPRPYQGVRVKEPVKELLKRKRGSLqnANGATAAATTvffpHQSLPSYSPAGQ--------VCADSEFVA 78  green anole
XP_546531      7 TAPEQAPa--PPRPYQGVRVKEPVKELLRRKRGHA--SSGAAVTPTAvvlpHQPLATYTTVGP--------SCLDMEVSA 74  dog
XP_007494916  20 SAPEQTPv--PPRPYQGVRVKEPVKELLRRKRGLA--SSGLTVAATTvvlpHQPLATYATMGP--------SCLDMEVPT 87  gray short-tail...

Q90ZH6        74 P--ALpgAEEGALCSSWLSQPSPSSLQPLTQWTTYPDYVSHEAASCPYTADMYIQPMCPSYTLVGPSSVLTYASQPLITN 151 chicken
XP_002932979  80 TalPL--HDEGALYTGWISQPPSAAFQPLTQWTTCPEYISHETVSCPYTGDMYVQPMCQGYTVVGPPSVLTYTSQPLLTN 157 western clawed ...
XP_008119288  79 S--PL--VDDGTLYSGWLAQPSPATLQPLTQWAAYPDYVPHEAVSCPYTGEMYVQPVCPSYTLVGTSSVLTYASQPLITN 154 green anole
XP_546531     75 S--TV--TEEGALCAGWLSQPGPATLQPLAPWTPYTEYVSHEAVSCPYSADMYVQPMCPSYTVVGPSSVLTYASQPLITN 150 dog
XP_007494916  88 S--TV--TEEGALCTGWLSQPAPATLQPLTPWTPYPEYMPHEGVSCPYSTDMYVQPVCPSYTVVGPSSVLTYASQPLITN 163 gray short-tail...

Q90ZH6       152 FTPRS-STPAVVPQLEVTEQQPPLTYFPWAQPLSALP--APTLQYQPASSTLPTPQFVPLPISIPEPAPQELEDARRVIG 228 chicken
XP_002932979 158 FAARS-ANPGVATQIEYTDHQGPLTYIPWAQPIATLPgaTHTIPYQTTSTTFQGTQFVPIPISLPEPVQQDLDDTRRVTN 236 western clawed ...
XP_008119288 155 LAARStSAPAVMPHLDMMEQQGPLSYFPWTQPISTLP--APSLQYQAASSALPAPQFLPLPVSVPETVSQDLEDTRKDLG 232 green anole
XP_546531    151 VTTRSaAAPAVGPQLEGPEHQAPLTYFPWPQPLSTLP--TSTLQYQPPAPALPGPQFVQLPISIPEPVLQDMEDPRRAIS 228 dog
XP_007494916 164 FTTRN-ATPTSGPQLEGTEHQAPLTYFSWPQPISALP--SSTLQYQSPAPSLPGPQFLPLPISIPEPVPQDLEDTRRAIN 240 gray short-tail...

Q90ZH6       229 TLPIEKLLLEDEDNDTYVLNHALSVEG 255 chicken
XP_002932979 237 DLPMEKLLQENEDNESYALSHALSIEG 263 western clawed frog
XP_008119288 233 GLSMEKLLLQEENHGIFDLSNSLPVEG 259 green anole
XP_546531    229 SLTIDKLLLEEEDGDAYALNHTLSVEG 255 dog
XP_007494916 241 TLPIEKLLLEEEESDTYGMNHTLSVEG 267 gray short-tailed opossum
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