Conserved Protein Domain Family
Fox-1_C
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pfam12414: Fox-1_C (this model, PSSM-Id:315148 is obsolete and has been replaced by 463568)
Calcitonin gene-related peptide regulator C terminal
This domain family is found in eukaryotes, and is typically between 69 and 99 amino acids in length. The family is found in association with pfam00076. This family is the C terminal of Fox-1, a protein involved in the regulation of calcitonin gene-related peptide to mediate the neuron-specific splicing pattern. Fox-1, with Fox-2, functions to repress exon 4 inclusion.
Links
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Statistics
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PSSM-Id: 315148
Aligned: 13 rows
Threshold Bit Score: 71.0023
Created: 28-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q642J5        228 VPGFPYPAAT-------AAAAAYRGAHLRGRGRT-VYNTFRaAAPPPHIPAYGGVVYQDGF-YGAD-IYGGY-------- 289 zebrafish
5_pfamImport    1 VPGFPYPTAA-------TTAAAFRGAHLRGRGRT-VYGAVR-AVPPTAIPAYPGVVYQDGF-YGAD-LYQGWgg------ 63 
2_pfamImport    1 IPGFPYPTAAaa----aTTAAAFRGAHLRGRGRT-VYGAVR-AVPPTAIPTYPGVLYQDGF-YGTE-LYGGY-------- 64 
3_pfamImport    1 VPGFPYPTAA-------TTAAAFRGAHLRGRGRT-VYGAVR-AVPPTAIPAYPGVVYQDGF-YGAD-LYGGY-------- 61 
4_pfamImport    1 LPGFPYPSAAaa---aaTTAAAFRGAHLRGRGRP-VYSAVRaAVPQPAIPTYPGVVYQDGF-YGAAdLYWGW-------- 67 
8_pfamImport    1 VPGFPYPSAAaattaaaAAAAAFRGAHLRGRGRP-VYSAVRaALPQPAIPAYPGLVFQDSV-LSARlPQGGYpaaaaaaa 78 
9_pfamImport    1 VASFPYPVAT--------PTLAYRGSALRGRGRA-VYNAIRsAAAPAAVPAFPGVVYQDGL-YGAE-VYGGYp------- 62 
11_pfamImport   1 VASIPYPMMA-------PAALAYRGA-LRGRGRAtIYNPIRaAPAPSPVPAYGSVLYPDGL-YGSD-IY-GYp------- 62 
10_pfamImport   1 LTGFPYPTAG--------AAVAYRGAHLRGRGRA-VYNTFRaAPPPPPIPTYGAILYLDNIaYKNN-IAGGY-------- 62 
7_pfamImport    1 VAGFPYPATG--------ATVAYRGAHLRGRGRA-VYNTFRtAPPPPPIPAYGAVVYQDGF-YGAE-IYGGY-------- 61 
6_pfamImport    1 VTGFPYPTTG--------TAVAYRGAHLRGRGRA-VYNTFRaAPPPPPIPTYGAVVYQDGF-YGAE-IYGGY-------- 61 
12_pfamImport   1 VPGFPYPTAAaaa--aaTTAATFRGAHLRGRGRP-VYGAVRaAVPQPAIPAYPGIVFQDTV-VSSRlPQGGY-------- 68 
1_pfamImport    1 MPGFPYPAAT--------AAAAYRGAHLRGRGRT-VYNTFRaAAPPPPIPAYGGVVYQEPV-YGNKlLQGGY-------- 62 

Q642J5        290 ---TAYRYTQ-----PATAT----------AAAYSDS-YGRVY-A-ADPY 318 zebrafish
5_pfamImport   64 --eISYRYVKkilrdRTSSTsls-----lpESQYSDG-YGRVY-T-ADPY 103
2_pfamImport   65 ---AAYRYTQlp--sPPTSAltalpvppltARMCTDReYGRVY-T-ADPY 107
3_pfamImport   62 ---AAYRYAQ-----PATATaata--aaaaAAAYSDG-YGRVY-T-ADPY 98 
4_pfamImport   68 ---ALYRYAQ-----PTAVTgat-----aaAAAYSDS-YGRVY-T-TDPY 101
8_pfamImport   79 aaaAAYRYTQ-----PATVTgat-----paAAAYSDS-YGRVY-T-TDPY 115
9_pfamImport   63 ---AAYRVAQ-----SASAA----------AATYSDG-YGRVYtTaADPY 93 
11_pfamImport  63 ---AAYRVAQ-----TPAAAaa------taAAAYSDG-YGRVYtT-AEPY 96 
10_pfamImport  63 ---AAYRYAQ-----PAAAA----------ATAYSDS-YGRVYtA-ADPY 92 
7_pfamImport   62 ---AAYRFAQ-----PTTTA------------AFSDS-YGRVYaT-ADPY 89 
6_pfamImport   62 ---AAYRYRL-----GQTAVleeg--spgsPKGWIQS-YGRVYaA-ADPY 99 
12_pfamImport  69 ---AAYRYAQ-----PTAVAgptaaaaaaaAAAYSDS-YGRVY-T-ADPY 107
1_pfamImport   63 ---AAYRYAQ-----PTPAT----------AAAYSDR-NQFVFvA-AD-- 90
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