Conserved Protein Domain Family
GPHR_N
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pfam12537: GPHR_N (this model, PSSM-Id:315250 is obsolete and has been replaced by 463623)
The Golgi pH Regulator (GPHR) Family N-terminal
GPHR_N is the N-terminal 5TM region of the Golgi pH regulator proteins in eukaryotes. It plays vital roles in the transport of newly synthesized proteins from the Golgi to the plasma membrane, in the glycosylation of proteins along the exocytic pathway and the structural organisation of the Golgi apparatus.
Links
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Statistics
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PSSM-Id: 315250
Aligned: 106 rows
Threshold Bit Score: 35.1812
Created: 28-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q17912        141 IFTIEQVISRVGVIGVTVMAVLSGFGAVNAPYSYMTI-----F-M------RPVE--------------------EIQAQ 188  Caenorhabditi...
Q8ILP5        281 FNFMKNLLTYMSVTGMTIVSALSAFTSLYSPYSNISN-----F-F------FFVN--------------------IKKVK 328  Plasmodium fa...
XP_002550215  191 RSFIEKIINQVSIVGITILAILSGVGSTSTPYKIFEK-----Y-KlinsddREVG--------------------ELDIN 244  Candida tropi...
XP_001387864  213 kTIIENKINEISIAGITILAVLSGIGSTSTPYKLFAWqklisR-I------REVT--------------------ESDIN 265  Scheffersomyc...
EMG47788      192 RNLIERIINQVSIVGITILAILSGVGSTSTPYKLFEK-----Y-QgsnddeRDIG--------------------ELEIN 245  Candida malto...
XP_013934635  203 slFFSNSLIEVTMLGVTCLAALNGIGSVSSLYYSFIK-----K-H------KRVR--------------------KTDIA 250  Ogataea parap...
XP_002492656  195 eGYLVRFLNQLALLGIMSLGALSGIISVSTPYNAYRK-----D-Q------QYIS--------------------VLDLK 242  Komagataella ...
XP_001526926  225 RNLMERKINEVSIVGITILAILSGAGSASTPYRVISM-----DsL------KKLTnykgansstlqtssnssegiERDIN 293  Lodderomyces ...
XP_006689571   95 RSLLDTKITQVGLMGITTNSVLSGIGSSTVIYKVISA-----W-Kfk--ssRGVS--------------------EKDIN 146  Candida tenui...
EMS13965       94 IFSLYGLLEKLAVIGIFISAILSGYSSIQLPMKHLDP-----F-H------KRYS--------------------DEQIK 141  Entamoeba his...

Q17912        189 QLEKRLKHAMDMIVSKKQK 207  Caenorhabditis elegans
Q8ILP5        329 VIEKKIKFIKQELSSKKKI 347  Plasmodium falciparum 3D7
XP_002550215  245 TAIQYFNNTSTLLAKREQE 263  Candida tropicalis MYA-3404
XP_001387864  266 AAIRYYNNTCSLLTRRAAD 284  Scheffersomyces stipitis CBS 6054
EMG47788      246 TAIQYFNNTSLLLNKRKAE 264  Candida maltosa Xu316
XP_013934635  251 RSVETLRTTTELIHTRTTE 269  Ogataea parapolymorpha DL-1
XP_002492656  243 NKARQLESIQDQLNTKLSR 261  Komagataella pastoris GS115
XP_001526926  294 LAIRNYNNTTLLLSKREQE 312  Lodderomyces elongisporus NRRL YB-4239
XP_006689571  147 GVISNYNNINVLLEKRNSE 165  Candida tenuis ATCC 10573
EMS13965      142 TKYAQLKFmeqrgetssel 160  Entamoeba histolytica HM-3:IMSS
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