cd07697: IgC_TCR_gamma (this model, PSSM-Id:319324 is obsolete and has been replaced by 409494)
T cell receptor (TCR) gamma chain constant immunoglobulin domain
IgC_TCR_gamma; immunoglobulin (Ig) constant (C) domain of the gamma chain of gamma-delta T-cell receptors (TCRs). TCRs mediate antigen recognition by T lymphocytes, and are heterodimers consisting of alpha and beta chains or gamma and delta chains. Each chain contains a variable (V) and a constant (C) region. The majority of T cells contain alpha-beta TCRs but a small subset contain gamma-delta TCRs. Alpha-beta TCRs recognize antigen as peptide fragments presented by major histocompatibility complex (MHC) molecules. Gamma-delta TCRs recognize intact protein antigens; they recognize protein antigens directly and without antigen processing, and MHC independently of the bound peptide. Gamma-delta T cells can also be stimulated by non-peptide antigens such as small phosphate- or amine-containing compounds.
Structure:1HXM_B; human gamma/delta T-cell receptor gamma chain IgC domain forms a heterodimer interface with the delta chain IgC domain, defined using 4.0 A contacts. - View structure with Cn3D
Jiyao W et al.(2023). "The conserved domain database in 2023.",