cd16472: RING-H2_RNF38_like (this model, PSSM-Id:319386 is obsolete and has been replaced by 438135)
RING finger, H2 subclass, found in RING finger proteins RNF38, RNF44, and similar proteins
The family includes RING finger proteins RNF38, RNF44, and similar proteins. RNF38 is a nuclear E3 ubiquitin protein ligase that plays a role in regulating p53. RNF44 is an uncharacterized RING finger protein that shows high sequence similarity with RNF38. Both RNF38 and RNF44 contain a coiled-coil motif, a KIL motif (Lys-X2-Ile/Leu-X2-Ile/Leu, X can be any amino acid), and a C3H2C3-type RING-H2 finger. In addition, RNF38 harbors two potential nuclear localization signals.
Jiyao W et al.(2023). "The conserved domain database in 2023.",