Conserved Protein Domain Family

cl25732: SMC_N Superfamily (this model, PSSM-Id:330553 is obsolete)
RecF/RecN/SMC N terminal domain
This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Taxonomy: root
PubMed: 26 links
Protein: Related Protein
Related Structure
Accession: cl25732
PSSM Id: 330553
Name: SMC_N
Created: 5-Dec-2016
Updated: 5-Dec-2016
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