pfam04377: ATE_C (this model, PSSM-Id:335756 is obsolete and has been replaced by 461282)
Arginine-tRNA-protein transferase, C-terminus
This family represents the C terminal region of the enzyme arginine-tRNA-protein transferase (EC 2.3.2.8), which catalyzes the post-translational conjugation of arginine to the N-terminus of a protein. In eukaryotes, this functions as part of the N-end rule pathway of protein degradation by conjugating a destabilizing amino acid to the amino terminal aspartate or glutamate of a protein, targeting the protein for ubiquitin-dependent proteolysis. N terminal cysteine is sometimes modified.
Jiyao W et al.(2023). "The conserved domain database in 2023.",