Conserved Protein Domain Family
Na_trans_assoc
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pfam06512: Na_trans_assoc (this model, PSSM-Id:336429 is obsolete and has been replaced by 461936)
Sodium ion transport-associated
Members of this family contain a region found exclusively in eukaryotic sodium channels or their subunits, many of which are voltage-gated. Members very often also contain between one and four copies of pfam00520 and, less often, one copy of pfam00612.
Links
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Statistics
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PSSM-Id: 336429
Aligned: 66 rows
Threshold Bit Score: 88.9095
Created: 26-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
Download Cn3D
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
P15390        810 DGEMNNLQIAIGRIKWGIGFAKTFLLGLLRGKIlspkeiilslgepggagenaeesTPEdEKKEPPP---Edke-lkDNH 885  Norway rat
XP_005317491  815 eARKTKVQLALDRFGRAFSFVIHTLEHFCCKRC-----------------------KRHnLPKLKEMtadSdaeskdIIP 871  thirteen-line...
XP_318122    1020 DNETNKIAEAFNRISRFSNWIKMNLANAL-----------------------------------------KfvknklTSQ 1058 Anopheles gam...
XP_017101604 1046 DNDTNKIAEAFNRIGRFKSWVKRNIADCF-----------------------------------------KlirnklTNQ 1084 Drosophila bi...
ABP96886      480 DQDTNKIAEAFNRISRFIDWIKRNVADFL-----------------------------------------KllknklTNQ 518  domestic silk...
EFA11577     1022 DNDTNKIAEAFDRIGRFIRWIKGNVLHIA-----------------------------------------KlvrfklTNQ 1060 red flour beetle
XP_016836968 1021 DNDTNKITEAIDRISRFIAWTKRNILNLL-----------------------------------------KmlrakfTNQ 1059 jewel wasp
XP_011266375 1044 DNDTNKIAEAIDRIARFINWIKRNILNIA-----------------------------------------KlmrakfTNQ 1082 Florida carpe...
XP_002427248  967 DNDTNKIAEAFNRISRFNAWVKRSILNFL-----------------------------------------KmlrakiSNQ 1005 human body louse
EFX81393     1003 DNDTNKLTEAFNRISRFKRWVRRSFSNGF-----------------------------------------RmirsklTNQ 1041 common water ...

P15390        886 ILNHvgLTDGPRSSIEldh--------------------lnFINN--PYLTIQVPIA----------------------- 920  Norway rat
XP_005317491  872 LAADmkRGSEAQEEFGvlns-----------------aqktFSLG--YDRSWLAPLA----------------------- 909  thirteen-line...
XP_318122    1059 IASV--QPTGkgvcpcissehgeneleltpddiladgllkkGIKEh-NQLEVA--IGdgmeftihgdlknkakk--nkqi 1131 Anopheles gam...
XP_017101604 1085 ISDQpsehgdnelelg-------------hdeiladglikkGIKEq-TQLEVA--IGdgmeftihgdmknskpk---ksk 1145 Drosophila bi...
ABP96886      519 IAIH--APervdnelelg-------------tdlddavlykDKKLk-DQVEVA--IGdgmeftipgdnkykk-------g 573  domestic silk...
EFA11577     1061 ISDQ------P-SDVRcdggldisg--------deiladgiIKKS--PKDRLEVTIGtgmdltvhgdpk----------- 1112 red flour beetle
XP_016836968 1060 ISDQ--APdgidrdmnmdla----------egeldayrdkkSVKElnNQFEVA--IGdgmeftihgdlknkmrt---slc 1122 jewel wasp
XP_011266375 1083 ISDQ--APGEGPSNSWkedgidrdgdldladgeldayrdkkSAKEl-NQLEVA--IGegmeftihgdlknklk----nkl 1153 Florida carpe...
XP_002427248 1006 IGDHtgLPdgrdrdtdlelg----------deilvdgmvfrDKKNskDQLEVA--IGdgmeftihgdfkeklrrskmaln 1073 human body louse
EFX81393     1042 ISDQrapgelplfqigpfyfqcg------lfvfnfrasgmpaalhirRHIEIVVKIAasclflicdesmsklk----nkk 1111 common water ...

P15390        921 -------------SEE-SDLEmp-----tEE---------ETDAFSEp------------------------EDIKKplQ 948  Norway rat
XP_005317491  910 -------------EEE-NDVEyf-----dKD---------DASSIMHseaerqaydlh---qekpaipgdqsVEIDVfpE 958  thirteen-line...
XP_318122    1132 mnnskvignsisnHQD-NKLD--------HElnhrgvslqDDDTASIksygshknrpfkdeshkgsaetmegEEKRD--- 1199 Anopheles gam...
XP_017101604 1146 ylnnatmignsinHQD-NRLE--------HElnhrglslqDDDTASInsygshknrpfkdeshkgsaetmegEEKRD--- 1213 Drosophila bi...
ABP96886      574 kilmnniyrithyHRD-NRLD--------CElnhhgypiqDDDTISQksygshkirsfkdeshkgsadtidgEEKKD--- 641  domestic silk...
EFA11577     1113 --rgknninksktIGN-SILEh-------GMyig----hlDEDEISNksygshknrfkeeshkgsvdmlddhEEKRD--- 1175 red flour beetle
XP_016836968 1123 lnntkalvnsinhHRD-FRLD--------HDymn----hnEDDTISNksygshknrsfkdeshkgsldsldgEEKKD--- 1186 jewel wasp
XP_011266375 1154 cmnntkviansinHHD-YRLD--------NDyin----qnEDDTISNksygshknrafkdeshkgsmdslngEEKKD--- 1217 Florida carpe...
XP_002427248 1074 nknnvignsyaglNSD-NRFE--------SDyit----hnEEDTYSNisygshrkriykdeshkgsidtfeeDEKGD--- 1137 human body louse
EFX81393     1112 ganntsavcpnstKKRpDELVldidcrknPK---------DDDTISYqsygshchritrdeshkgslrvdyyDEKRN--- 1179 common water ...

P15390        949 PLY-------------DGNSSVCSTADYKPPEEDPEEQAEENPEGEQ---------------------PEECFTEACVKR 994  Norway rat
XP_005317491  959 EEVylavqnprkksdaISIPSECSTIDLQEA---FGYLYRIVPQQKQ---------------------PERCLPKGLHCF 1014 thirteen-line...
XP_318122    1200 ------------------ASKEDLGID-----EELDDEGEGDEGPLDgeliihae-----edeviedsPADCCPDNCYKK 1251 Anopheles gam...
XP_017101604 1214 ------------------ASKEDLGLD-----EELDEEGECEEGPLDgdiiihah-----dedildeyPADCCPDSYYKK 1265 Drosophila bi...
ABP96886      642 ------------------ASKEELGLE-----EELIEEDE--EGKLDgtlgktdikv-gadedvvddtPADCCPEQCYQK 695  domestic silk...
EFA11577     1176 ------------------ASKEELGIG----EEETEDDRFDLEKPLTdivivgna-----ddiiiddyAADCFPDSCYKK 1228 red flour beetle
XP_016836968 1187 ------------------ASKEDLEDDLDDEGEDEDEEEEEVEE-IPcriikqde------eldgensPSDCCPDNCYQR 1241 jewel wasp
XP_011266375 1218 ------------------ASKEDLEQE----GEDLEDEGEEGEE-VDidiiqaee------dpiqdnyPSDCCPENCYKK 1268 Florida carpe...
XP_002427248 1138 ------------------MSKEE---------DEEMDEEEEGESIPEidviidanm----edvmlqdyPSDCCPDHCYKR 1186 human body louse
EFX81393     1180 ------------------ASKE----DLDGFPEEARPAEVEGEDDGLaaeaavvkiahrvdsdedpqyPDACFPDHWYEK 1237 common water ...

P15390        995 CPCLYVDISQGRGKMWWTLRRACF 1018 Norway rat
XP_005317491 1015 FPCCRKDRRKSLWVIWWNLRKTCY 1038 thirteen-lined ground squirrel
XP_318122    1252 FPVLAGDDDAPFWQGWGNLRLKTF 1275 Anopheles gambiae str. PEST
XP_017101604 1266 FPILAGDEDSPFWQGWGNLRLKTF 1289 Drosophila bipectinata
ABP96886      696 FPFLAGDDDSPFWQGWGTLRLKTF 719  domestic silkworm
EFA11577     1229 FPFLAGDEDSPFWQGWGNLRSKTY 1252 red flour beetle
XP_016836968 1242 FPFLAGDDDAPFWQGWATLRLKTF 1265 jewel wasp
XP_011266375 1269 FPFLAGDDDAPFWQGWANLRLKTF 1292 Florida carpenter ant
XP_002427248 1187 FPFLAGDDDAPFWQGWSNLRLKTF 1210 human body louse
EFX81393     1238 IPIIKGNDDSPFWQGWAMLRLKTF 1261 common water flea
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