1T2A_A 28 LITGITGQDGSY-LAEFLL-EK--GYEVHGIVR--RSSSFNTGRIEHLYKNpqAHIEGNMKLHYGDLTD-STCLVKIINE 100 human Q4CYB9 25 LVTGGLGFIGSN-FINHLL-RThsGVHVYNLDKvdYCSSFR--SIEN-PSDpyYH------FVRGNITN-ADLVMYVLRH 92 Trypanosoma cruzi ERG84349 8 LVTGGCGFIGSN-FINYIF-HV--WPDVHFVNC--DKLIL---NSDACYVDeeVRSSERYQLVTADIRN-SEVVRRILNE 77 pig roundworm EDK41767 20 LVTGGAGFIGSH-TLDYLV-QK--YPDCKFTCV--DKLSYATNYSENNLRKvsGC--DNFTFIKLDLAEeHQRLDELINH 91 Meyerozyma guil... WP_012319347 4 LVTGGCGFIGSA-LVLHLVnDL--GHDVCTLDA--MTYAANPVSLAPLADNprH------RLVEADICD-RAAVQKAYAD 71 eubacteria WP_006249515 4 LITGGAGFIGSA-LVRYLI-EH----TPHTVIN--VDKLTYAGNLASLESVa---hHERYHFEKADICA-SGQISEIFGK 71 Mannheimia haem... WP_005547278 6 LVTGGAGFIGSA-VVRYII-EN--TQDS--VVN--VDKLTYAGNLESLET---VKNNPRYIFEQVDICD-AKALARIFEQ 73 Aggregatibacter... WP_050764216 5 LVTGGAGFIGSA-VVRHLI-EDt-PHEVCVLDK--LTYAGNLDNLEPVAKNprYRF------KQVDICD-RAAVATLIAS 72 Beijerinckia in... WP_013031028 5 LVTGGAGFIGSAvIRQFIN-DT--ACSVVNVDK--LTYAGNLQSLASVSDNprYRFE------QVDICD-AAEVARVFRE 72 Sideroxydans li... CBE69853 4 LVTGGAGFIGSN-FIRHLL-AT--ESACH-VVN--LDKLTYAGNLENLTD---VEHDPRYRFVKGSICD-ALLVDELLKE 72 Candidatus Meth...
1T2A_A 101 V--KPTEIYNLGAQSHVKISFDLAEYTADVDGVGTLRLLDAVK----TC-----G--LI------N-----SVKFYQAST 156 human Q4CYB9 93 H--DIDTIINFAAQSHVDNSFGNSLSFTYNNVLGTHVLLECAR----TY-----G--RI------E-------KFIHVST 146 Trypanosoma cruzi ERG84349 78 N--KIDTVVHFAADCTSTRCYGDPIESVENNVIAFIKLLDAVR----EY-----G--AV-------------KRFIHIST 131 pig roundworm EDK41767 92 SanNFTTIINFAAESCVDKSFNDPLYFTKNNVLATQNLLECCR----TLlnskpN--LR------R-----NFKFIHIST 154 Meyerozyma guil... WP_012319347 72 F--KPEAVMHLAAESHVDRSITDPGAFVRTNVIGTQTMLDGARghyeTLp---eA--EK------R-----TFRFLHVST 133 eubacteria WP_006249515 72 Y--QPDVVMHLAAESHVDRSISGAADFIQTNIVGTYTLLEAAR----AY-----W--DTlpeprkS-----AFRFLHIST 133 Mannheimia haem... WP_005547278 74 H--QPDVVMHLAAESHVDRSIDGPAAFIETNIVGTYILLEAAR----AY-----W--SSlndekkA-----GFRFHHIST 135 Aggregatibacter... WP_050764216 73 Y--QPRIIMHLAAESHVDRSIDGPAAFIETNLVGTFTLLEAAR----CF-----WqdLP------Gee-kaAFRFHHVST 134 Beijerinckia in... WP_013031028 73 H--QPDAVMHLAAESHVDRSISGPADFIQTNIIGTYTLLEAAR----GYw----N--SL------DgerkaGFRFHHIST 134 Sideroxydans li... CBE69853 73 G--F-DALINFAAESHVDRSIQDARAFTETNVLGTQVMLDACR----R----------H------R-----VPRMMQVST 124 Candidatus Meth...
1T2A_A 157 SELYGKVQ----EIP-Q-KETTPFYPRSPYGAAKLYAYWIVVNFREAYNL----FAVNGILFN----------------- 209 human Q4CYB9 147 DEVYGQVT----DSK-K-EE-GTLNPTNPYAATKAAVEYIVKSYHISFGL----PCIIT---R----------------- 195 Trypanosoma cruzi ERG84349 132 DEVYGDSDlsedEKG-K-LEDSLLLPGNPYAATKAACESYAHMYRQQFGI----PIVILRINNiygpnqwdvkaccycyc 205 pig roundworm EDK41767 155 DEVYGEQK----EGEiI-DEDGPLHPTNPYAASKAACDLIIEAYKHSYKIpitlIRSNNVYGP----------------- 212 Meyerozyma guil... WP_012319347 134 DEVYGSLPp---DAF-F-TEESRYDPRSPYSASKAASDHLARAWHETYGL----PVLVTNCSN----------------- 187 eubacteria WP_006249515 134 DEVYGDLAk--sEEL-F-TEKTPYNPSSPYSASKAASDHLARAWHRTYGL----PTVITNCSN----------------- 188 Mannheimia haem... WP_005547278 136 DEVYGDLDg--tKNL-F-TETTPYSPSSPYSASKASSDHLVRAWLRTYSL----PTIVTNCSN----------------- 190 Aggregatibacter... WP_050764216 135 DEVFGSLGa---DGF-F-QETTAYQPNSPYSASKAGSDHLVRAWGHTYGL----PTVTSNCSN----------------- 188 Beijerinckia in... WP_013031028 135 DEVYGSLG----DTGfF-TEETAYEPNSPYSASKASSDHLVRAWHHTYGF----PVVTTNCSN----------------- 188 Sideroxydans li... CBE69853 125 DEVYGSLG----AFG-RfTEESPLHSNSPYAASKAAGDLLALAYCRTYGL----PVIITRSSN----------------- 178 Candidatus Meth...
1T2A_A 210 --HESPRRGANF--------VTRKISRSVAKIYLGQ-LECFSL-GNLDAKRDWGHAKDYVEA---MWLMLQN--DEPEDF 272 human Q4CYB9 196 --GNNVYGPYQY--------PEKLIPRFIMLMNAGK-K-LTIQ-GNGSNKRTFIHASDVARA---FVAIINH------GF 253 Trypanosoma cruzi ERG84349 206 fcHYSWS----LepsqfksnVFEVVPRFI-EIAKNR-ENFTIQ-GSGKQLRSWLYADDASEG---IRAAVER--G----- 268 pig roundworm EDK41767 213 --RQFPEKIIP---------VCLKALQKASPTGIAE-KERIPIhGNGRHTRRYLHVLDFAKAvdhIWNWLKNtsESSSDF 280 Meyerozyma guil... WP_012319347 188 --NYGPR---HF--------PEKLIPLMILNALEGKkLPVY---GDGLNERDWIHVEDHAKG---LVAVLER--GRIGET 246 eubacteria WP_006249515 189 --NYGAYQ---Y--------PEKLIPLMILNALEGK--SLPVY-GNGLQVRDWLFVEDHIRA---LYLVLQK--GQ---- 243 Mannheimia haem... WP_005547278 191 --NYGPF---HF--------PEKLIPLIILNALDGK--PLPVY-GNGQQIRDWLFVEDHARA---LYKVVTE--GK---- 245 Aggregatibacter... WP_050764216 189 --NYGPY---HF--------PEKLIPLMILNALEGK-P-LPVY-GNGQNIRDWLYVEDHARA---LVAIALA--GRP--- 244 Beijerinckia in... WP_013031028 189 --NYGPY---HF--------PEKLIPLVILNAVNGKpLPI--Y-GKGDNIRDWLYVDDHARA---LRLVLER--GK---- 243 Sideroxydans li... CBE69853 179 --NYGPHQ---F--------PEKVIPLFITNALVGEpLPLY---GDGLHIRDWLHVRDHCEA---LALILNN--G----- 232 Candidatus Meth...
1T2A_A 273 VIATGEVHSVREFVEKSFLHIGKTIVWE-GK--NENEVGRCKETGKVHV-T-VDLKYYRPTEVDFL-QGDCTKAK-QKLN 345 human Q4CYB9 254 I---GDVYNIGSCDEKSVLDIARMTVKY-VRahKCGEREPLADPSEEEV-S-RHLVFVKDREFNDE-RYDISVEKlQELG 326 Trypanosoma cruzi ERG84349 269 --AVGEIYNLGTYFELNMLDVAREVQVE-----VDKQLGRE--PSP--V-H-FVSIPDRPYNDLRY-LIDITKAY-DELG 333 pig roundworm EDK41767 281 LGETFNVGTDDEVDNLSMVKLICTIFMR-KK--F--GVESLDASSFIRH-T-KDRNYN-----DFRySIDFTKIK--KVG 346 Meyerozyma guil... WP_012319347 247 YLLGGR-------AVRNNLAVVKALCAA---------FDRLRPQGAPHEqL-ISFVADRPGHDRRY-AIDCTKAE-TELG 307 eubacteria WP_006249515 244 ---IGETYNIGGHNEKTNIEVVRSICSI--L--QEMVPNNPLVVGQYAD-L-ITYVQDRPGHDFRY-AIDTSKIE-KELD 312 Mannheimia haem... WP_005547278 246 ---IGETYNIGGHNEKANIDVVRTICAL--L--EELVPNKPAGVTKYED-L-ITYVKDRPGHDVRY-AIDATKIS-RELG 314 Aggregatibacter... WP_050764216 245 ----GESYNVGGWNERANIDVVQAVCA------LVDEMAPDAAIGPREK-L-ITFVTDRPGHDARY-AIDATKIK-QDLG 310 Beijerinckia in... WP_013031028 244 ---LGETYNIGGWNEKTNLEVVLAICA--AL--DEL-----RPQGAPHN-KlITYVADRPGHDKRY-AIDATKLA-RDLG 308 Sideroxydans li... CBE69853 233 --VSGEIYNIGGRCERANIDVARFILRTlGK--PDTL--------IAHV-K-DRLGHDRRYAL------DASKLE-QALG 291 Candidatus Meth...
1T2A_A 346 WKPRVAFDELVREM 359 human Q4CYB9 327 WRQEVRFEEGYKET 340 Trypanosoma cruzi ERG84349 334 WSPKIPFNEGIRRv 347 pig roundworm EDK41767 347 WKQEISLEQGIEEL 360 Meyerozyma guilliermondii ATCC 6260 WP_012319347 308 WRPQKTFEQALEET 321 eubacteria WP_006249515 313 WKPKETFESGLRKT 326 Mannheimia haemolytica WP_005547278 315 WKPQETFESGIRKT 328 Aggregatibacter actinomycetemcomitans WP_050764216 311 WTPRETFETGLRKT 324 Beijerinckia indica WP_013031028 309 WKPQETFETGLRKT 322 Sideroxydans lithotrophicus CBE69853 292 WSPRIAFEAGLEET 305 Candidatus Methylomirabilis oxyfera
Jiyao W et al.(2023). "The conserved domain database in 2023.",