1ION,3Q9L,1HYQ,4V03,4V02,1G3Q,3R9J


Conserved Protein Domain Family
MinD
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cd02036: MinD 
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septum site-determining protein MinD
Septum site-determining protein MinD is part of the operon MinCDE that determines the site of the formation of a septum at mid-cell, an important part of bacterial cell division. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal role, selecting the mid-cell over other sites through the activation and regulation of MinC and MinE. MinD is a membrane-associated ATPase, related to nitrogenase iron protein.
Links
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Statistics
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PSSM-Id: 349756
Aligned: 27 rows
Threshold Bit Score: 256.36
Created: 15-Dec-2004
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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Conserved site includes 20 residues -Click on image for an interactive view with Cn3D
Feature 1:active site [active site]
Evidence:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1              #######                     #    #                                     
1ION_A      3 RIISIVSGKGGTGKTTVTANLSVALGExGRKVLAVDGDLTXANLSLVLGVDdv-nITLHDVLAGdaKLEDAIYXTqf--e 79  Pyrococcus horikoshii
3Q9L_A      3 RIIVVTSGKGGVGKTTSSAAIATGLAQkGKKTVVIDFAIGLRNLDLIMGCErrvvYDFVNVIQGdaTLNQALIKDkrt-e 81  Escherichia coli K12
1HYQ_A      3 RTITVASGKGGTGKTTITANLGVALAQlGHDVTIVDADITMANLELILGMEgl-pVTLQNVLAGeaRIDEAIYVGpg--- 78  Archaeoglobus fulg...
4V03_A      3 EVIVITSGKGGVGKTTLTANIGTALAKlGKKVLLIDADIGLRNLDMILGLEnrivYDILDVLEGrvPYEKALVKDkrg-l 81  Aquifex aeolicus
4V02_A      3 EVIVITSGKGGVGKTTLTANIGTALAKlGKKVLLIDAAIGLRNLDMILGLEnrivYDILDVLEGrvPYEKALVKDkrg-l 81  Aquifex aeolicus
1G3Q_A      3 RIISIVSGKGGTGKTTVTANLSVALGDrGRKVLAVDGDLTMANLSLVLGVDdp-dVTLHDVLAGeaNVEDAIYMTqf--d 79  Pyrococcus furiosus
CAB49485    4 RSIVFASGKGGTGKTTTVANIGVALAQfGKDVILIDADITMANLSLILGMEdi-pVTLHDVLAGeaDLKDAIYEGpa--- 79  Pyrococcus abyssi GE5
Q9X2I3      3 NVIVVTSGKGGVGKTTITANLGCALAKlGEKVCLIDADIGLKNLDIVLGLEnrivYTMIDVVNGkvSPQEALVKHkml-k 81  Thermotoga maritima
BAB81844    3 VSIVITSGKGGVGKTTTTANIGTALAAqGKKVVVVDGDTGLRNLDVLMGLEnrivYTVIDVIENrcRTKQALIRDkrf-n 81  Clostridium perfri...
Q01464      3 EAIVITSGKGGVGKTTTSANLGTALAIlGKRVCLVDTDIGLRNLDVVMGLEnriiYDLVDVVEGrcKMHQALVKDkrfdd 82  Bacillus subtilis

Feature 1                                             #                         #             
1ION_A     80 nVYILPGAvdwehvikadprKLPEVIKSLKGk--YDFILIDCPAGLQLRAXSAXLSGEEAILVTNPEISCLTDTXKVGXV 157 Pyrococcus horikoshii
3Q9L_A     82 nLYILPASqtrdkd-altreGVAKVLDDLKAm-dFEFIVCDSPAGIETGALMALYFADEAIITTNPEVSSVRDSDRILGI 159 Escherichia coli K12
1HYQ_A     79 gVKVVPAGvsleglrkanpeKLEDVLTQIMEs--TDILLLDAPAGLERSAVIAIAAAQELLLVVNPEISSITDGLKTKIV 156 Archaeoglobus fulg...
4V03_A     82 sLWLLPANqrankd-vidieKWNKTVEEIKNsgnYDYILVDSPAGIEKGFQIAVSPADKALIVVNPEVSSIRDADRVIGL 160 Aquifex aeolicus
4V02_A     82 sLWLLPANqrankd-vidieKWNKTVEEIKNsgnYDYILVDSPAGIEKGFQIAVSPADKALIVVNPEVSSIRDADRVIGL 160 Aquifex aeolicus
1G3Q_A     80 nVYVLPGAvdwehvlkadprKLPEVIKSLKDk--FDFILIDCPAGLQLDAMSAMLSGEEALLVTNPEISCLTDTMKVGIV 157 Pyrococcus furiosus
CAB49485   80 gVKVIPGGlslekikkaraeRLRDLIREISQm--GDFILIDAPAGLELTSITALLIGKELIIVTNPEIAAITDSLKTKLV 157 Pyrococcus abyssi GE5
Q9X2I3     82 nLYLLPASqiatke-mispnDMKAIVKELIPh--FDYIIIDSPAGIERGFRNAVAPAERVLVVTTPELPAISDADRVIGL 158 Thermotoga maritima
BAB81844   82 nLYLLPTAqtkdkn-dispeQMLRLVNELKEe--FDYVILDCPAGIEQGFENAIVGADRAIVVVNPEITSVRDADRVIGK 158 Clostridium perfri...
Q01464     83 lLYLMPAAqtsdkt-avapeQIKNMVQELKQe--FDYVIIDCPAGIEQGYKNAVSGADKAIVVTTPEISAVRDADRIIGL 159 Bacillus subtilis

Feature 1                          ##                            ####  ##  #                  
1ION_A    158 LKkag--------laiLGFILNRyg----rsERDIPPEAAQDVXDVPLLAVIPEDPVIREGTLeGIPAVkykPESKGAQA 225 Pyrococcus horikoshii
3Q9L_A    160 LAsksrraengeepikEHLLLTRynpgrvsrGDMLSMEDVLEILRIKLVGVIPEDQSVLRASNqGEPVIl-dINADAGKA 238 Escherichia coli K12
1HYQ_A    157 AErlg--------tkvLGVVVNRit----tlGIEMAKNEIEAILEAKVIGLIPEDPEVRRAAAyGKPVVlrsPNSPAARA 224 Archaeoglobus fulg...
4V03_A    161 LEsmd--------krnYKVIVNRikwemvkrGAMLSVEDIVDILKAEIIGIIPEEPKLVDFTNrGEPIVl-dEKFPASQA 231 Aquifex aeolicus
4V02_A    161 LEsmd--------krnYKVIVNRikwemvkrGAMLSVEDIVDILKAEIIGIIPEEPKLVDFTNrGEPIVl-dEKFPASQA 231 Aquifex aeolicus
1G3Q_A    158 LKkag--------laiLGFVLNRyg----rsDRDIPPEAAEDVMEVPLLAVIPEDPAIREGTLeGIPAVkykPESKGAKA 225 Pyrococcus furiosus
CAB49485  158 AEklg--------tlpLGAILNRvt----seKTELSREEIEALLEVPVLGTVPEDPEVKRASAyGVPLVvknPTSPAAIA 225 Pyrococcus abyssi GE5
Q9X2I3    159 LEnfgf------sdekINVIINRfkphmvkkGEMLTTDDIKHTLSLEIIAVIPDSEDIIVASNtGIPVSl-nGNSRISKN 231 Thermotoga maritima
BAB81844  159 LDakg--------lenHEVIVNRlnyemtkkGDMLDISDIIETLSVKLLGVVPDDRNITVSTNkGEPIVl-dEKASAGQA 229 Clostridium perfri...
Q01464    160 LEqeen-------iepPRLVVNRirnhlmknGDTMDIDEIVQHLSIDLLGIVADDDEVIKASNhGEPIAm-dPKNRASIA 231 Bacillus subtilis

Feature 1             
1ION_A    226 FIKLAEEV 233 Pyrococcus horikoshii
3Q9L_A    239 YADTVERL 246 Escherichia coli K12
1HYQ_A    225 IVELANYI 232 Archaeoglobus fulgidus
4V03_A    232 IIDTARRL 239 Aquifex aeolicus
4V02_A    232 IIDTARRL 239 Aquifex aeolicus
1G3Q_A    226 FVKLAEEI 233 Pyrococcus furiosus
CAB49485  226 YKEIAAKL 233 Pyrococcus abyssi GE5
Q9X2I3    232 FENLARRI 239 Thermotoga maritima
BAB81844  230 FRNIGRRI 237 Clostridium perfringens str. 13
Q01464    232 YRNIARRI 239 Bacillus subtilis

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