1NIP,2YNM,3FWY


Conserved Protein Domain Family
NifH-like
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cd02117: NifH-like 
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NifH family
This family contains the NifH (iron protein) of nitrogenase, L subunit (BchL/ChlL) of the protochlorophyllide reductase, and the BchX subunit of the Chlorophyllide reductase. Members of this family use energy from ATP hydrolysis and transfer electrons through a Fe4-S4 cluster to other subunit for substrate reduction
Links
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Statistics
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PSSM-Id: 349761
Aligned: 10 rows
Threshold Bit Score: 312.377
Created: 16-Feb-2005
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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Conserved site includes 19 residues -Click on image for an interactive view with Cn3D
Feature 1:active site [active site]
Evidence:
  • Structure:3FWY; Rhodobacter light-independent protochlorophyllide reductase with bound MgADP, contacts at 4A
    - View structure with Cn3D
  • Structure:2YNM; Prochlorococcus marinus light-independent protochlorophyllide reductase with bound MgADP, contacts at 4A
    - View structure with Cn3D
  • Structure:1NIP; Azotobacter vinelandii nitrogenase iron protein binds MgADP, contacts at 4A
    - View structure with Cn3D
  • Citation:PMID 1529353
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1            ########                     # # #                                       
1NIP_A      3 RQCAIYGKGGIGKSTTTQNLVAALAEmgkKVMIVGCDPKaDSTRLilhskaqntimemaaeagtvedleledvlkagygG 82  Azotobacter vinela...
2YNM_A     35 LVIAVYGKGGIGKSTTSSNLSAAFSKlgkKVLQIGCDPKhDSTFTlthkmvptvidileevdfhseelrpqdfmfegfnG 114 Prochlorococcus ma...
3FWY_A     49 KVFAVYGKGGIGKSTTSSNLSAAFSIlgkRVLQIGCDPKhDSTFTltgslvptvidvlkdvdfhpeelrpedfvfegfnG 128 Rhodobacter sphaer...
OGR95559    2 ENIVFFGKGGIGKSTIASNVTAALAQgsaRILHVGCDPKmDSSVSlmgrgippftssglle---deetlrksihpspvnG 78  Elusimicrobia bact...
OGR51592    2 ESIVFFGKGGIGKSTVASNVSAILAArgrKVLHVGCDPKgDSTLAltgrrvkhfadggvfa---geqalrasihpslfkN 78  Elusimicrobia bact...
OGR61413    2 ESLVFFGKGGIGKSTIASNLSALYGIsgkKVLHVGCDPKhDSSVSlcpegyvrtfmeqlledgtprlaegrpltlrgrfG 81  Elusimicrobia bact...
OGR43338    3 ERIVVLGKGGIGKSTIAANLSELYALggrRVLHIGCDPKgDSALLltggagiptvveslr----agapvfeellfstgrG 78  Elusimicrobia bact...
P26177     36 QIIAIYGKGGSGKSFTLANLSHMMAEmgkRVLLIGCDPKsDTTSLlfggkncptiietatkkklageevkvgdvcfksgG 115 Rhodobacter capsul...
OGS11934    2 ESIVFFGKGGIGKSTIASNITAILAAggrKILHVGCDPKmDCTLSlmgrhiqpftakcggp---gqsglrdsiypaavkG 78  Elusimicrobia bact...
OGR47824    1 MTLVVYGKGGVGKSTMCAHLAMCFARegrKVLLLGCDPKaDTSLRllggkrpptivdmvtg---lkgyrfqelavrsrpG 77  Elusimicrobia bact...

Feature 1                                                                                     
1NIP_A     83 VKCVESGGPepGVGCAGRGViTAINFLEeegay-eddlDFVFYDVlGDVVCGGFAMPIRenkAQEIYIVCSGEMMAMYAA 161 Azotobacter vinela...
2YNM_A    115 VQCVESGGPpaGTGCGGYVTgQTVKLLKehhl--ledtDVVIFDVlGDVVCGGFAAPLQh--ANYCLIVTANDFDSIFAM 190 Prochlorococcus ma...
3FWY_A    129 VMCVEAGGPpaGTGCGGYVVgQTVKLLKqhhl--lddtDVVIFDVlGDVVCGGFAAPLQh--ADQAVVVTANDFDSIYAM 204 Rhodobacter sphaer...
OGR95559   79 VFCIEAGGPdpGLGCAGAGIsAMLDTIRsvallekdryDAVIFDVlGDVVCGGFAAPLRrgfAQKAVIVVSEEILALYAA 158 Elusimicrobia bact...
OGR51592   79 INCVEAGGPqaGVGCAGAGIgAMLDIMKefsvlekdgyDAVVFDVlGDVVCGGFAAPLRrglAGKAVIVVSEEMLSLYAA 158 Elusimicrobia bact...
OGR61413   82 VDIVEAGGPepGVGCAGRGIsLMLETFQarkllengryEVVVFDIlGDVVCGGFATPIRrgfGKKVFIVVSEELMSLYAA 161 Elusimicrobia bact...
OGR43338   79 IDCLEAGGPapGEGCAGLGLlKTFELLEankekvdagyDVVLFDVlGDIVCGGFAVPLRkgfGRKVLIVVSDDLMSLYAA 158 Elusimicrobia bact...
P26177    116 VFAMELGGPevGRGCGGRGIiHGFELLEklgfh-dwdfDFVLLDFlGDVVCGGFGLPIArdmAQKVIVIGSNDLQSLYVA 194 Rhodobacter capsul...
OGS11934   79 AWCIEAGGPqpGVGCGGTAIgSMLDAMRderlleddgyDTAVFDVlGDVVCGGFAAPLRrgfAKKVIIVTSEEVLSLYAA 158 Elusimicrobia bact...
OGR47824   78 LDILETGGPqpGQGCGGRSVaTLCQYLEehare-lsgyDTLIFDVlGDLVCGGFVAPLRfgfGRDVYIVSSEETASLFAA 156 Elusimicrobia bact...

Feature 1                             ##                        ###   ##  #                   
1NIP_A    162 NNISKGIVKYAnsg-svRLGGLICNSrntdredELIIALANKLgtqMIHFVPRdnvVQRAEIR--RMTVIEydp----ka 234 Azotobacter vinela...
2YNM_A    191 NRIVAAINAKAkny-kvRLGGVIANRsa---elDQIEKFNEKTglkTMAHFRNvdaIRRSRLK--KCTIFEmdpeeegvl 264 Prochlorococcus ma...
3FWY_A    205 NRIIAAVQAKSkny-kvRLAGCVANRsr---atDEVDRFCKETnfrRLAHMPDldaIRRSRLK--KKTLFEmdedq-dvl 277 Rhodobacter sphaer...
OGR95559  159 NRLVKMVENYSrn--gvYLAGLAANLkna-dglKIVQDFARAVntkVLGVVLRsaeITRAEKAq-RVAVLHaph-----s 229 Elusimicrobia bact...
OGR51592  159 NKLVAMVNNYArn--gvWLAGLAVNAkdq-aavRLAQAFAAAArtrVLGMIPRdpaVARAEKMhrPVTVTDar------s 229 Elusimicrobia bact...
OGR61413  162 NNIAKAVRSYRdg--gvVLAGLVANVrdpeadpRPIARFAARIgtkVVASIPRdpaVREAEYR--RRSVVEhap----rs 233 Elusimicrobia bact...
OGR43338  159 NNIARAMGTYShg--gaRLLGLVANGvga-gggGMVDRFAKLVnvkTIGYCPAdpaVREAEGL--GVTVVRa-------- 225 Elusimicrobia bact...
P26177    195 NNVCNAVEYFRklggnvGVAGIVINKdd---gtGEAQAFAREVgipILAAIPAdeeLRRKSAA--YQIVGSha------t 263 Rhodobacter capsul...
OGS11934  159 NRLIMMVDNYSrn--gvYLAGLAVNVknp-gavVIARDFAKAVntrILGVMLRdpaVTAAERAh-KPAALAy-------- 226 Elusimicrobia bact...
OGR47824  157 NNIVRVAAEPYlq--gvSVGGIIFNLrqndarrEVLEAFAARLgvpIAAVMLRdpaILDAEED--GVTVFDhkp----gk 228 Elusimicrobia bact...

Feature 1                                               
1NIP_A    235 kQADEYRALARKVVDnkllvi-------pnpitmDELEELLM 269 Azotobacter vinelandii
2YNM_A    265 eVQNEYLSLAKKMIDnveple-------aeplkdREIFDLLG 299 Prochlorococcus marinus
3FWY_A    278 aARAEYIRLAESLWRgldpid-------phslpdRDIFELLG 312 Rhodobacter sphaeroides 2.4.1
OGR95559  230 dAARRLRALSRAIASarppaap------cralsdPEIFAFLK 265 Elusimicrobia bacterium GWF2_62_30
OGR51592  230 pAAAAMVRLAAAIQNakkpevs------prplsdQEFQELFT 265 Elusimicrobia bacterium GWA2_62_23
OGR61413  234 pAARALARLSALALRidprripvpapledrafyeLSLRQFRG 275 Elusimicrobia bacterium GWA2_69_24
OGR43338  226 sPASPFSRAVSGIKDavdrdaggn--slpkpldgRMLFSILS 265 Elusimicrobia bacterium GWA2_56_46
P26177    264 pWGKLFEELAGNVADapplrp--------rplspDALLALFE 297 Rhodobacter capsulatus SB 1003
OGS11934  227 -AKSDFARRAWQLSQainaagapa--tpprampdAEFFAFAE 265 Elusimicrobia bacterium RIFOXYA12_FULL_57_11
OGR47824  229 rAAGRFAALAASIAArrgavpg-----akvrpmsSEEFQSFV 265 Elusimicrobia bacterium GWA2_66_18

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