Conserved Protein Domain Family
DEXHc_SMARCA2
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cd18063: DEXHc_SMARCA2 
DEXH-box helicase domain of SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2, also known as brahma homolog) is a component of the BAF complex. SMARCA2 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Links
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Statistics
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PSSM-Id: 350821
Aligned: 5 rows
Threshold Bit Score: 496.508
Created: 27-Jul-2017
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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ATP bindingDEAD box
Feature 1:ATP binding site [chemical binding site]
Evidence:
  • Comment:based on the structure of Saccharomyces cerevisiae Chd1 with bound gamma-thio-ATP
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                                           #######                       
P51531        701 YYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMehkrlnGPYLIIV 780  human
Q6DIC0        706 YYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMehkrlnGPYLIIV 785  house mouse
NP_990470     697 YYTVAHAITERVEKQSSLLINGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMehkrlnGPYLIIV 776  chicken
XP_004910846  683 YYGVAHAVTERVEKQSSLLINGSLKHYQIQGLEWMVSLFNNNLNGILADEMGLGKTIQTIALITYLMehkrlnGPYLIIV 762  western clawe...
NP_001038240  703 YYGVAHAVIERVDKQSTFLINGTLKQYQIQGLEWMVSLYNNNLNGILADEMGLGKTIQTIGLITYLMehkrlnGPYLIIV 782  zebrafish

Feature 1                   #                                                           ##        
P51531        781 PLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLrsgKFNVLLTTYEYIIKdkhiLAKIRWKYMIVDEGHRMKnhh 860  human
Q6DIC0        786 PLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLrsgKFNVLLTTYEYIIKdkhiLAKIRWKYMIVDEGHRMKnhh 865  house mouse
NP_990470     777 PLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLrsgKFNVLLTTYEYIIKdkhiLAKIRWKYMIVDEGHRMKnhh 856  chicken
XP_004910846  763 PLSTLSNWLYEFDKWAPSVVKIAYKGTPAMRRSLVPQLrtgKFNVLLTTYEYIIKdkhiLAKIRWKYMIVDEGHRMKnhh 842  western clawe...
NP_001038240  783 PLSTLSNWVYELDKWAPSIVKIAYKGTPSMRRSLVPQLrsgKFNVLITTYEYIIKdkhiLAKIRWKYMIVDEGHRMKnhh 862  zebrafish

Feature 1                                                                                         
P51531        861 CKLTQVLNTHYvaPRRILLTGTPLQNKLpELWALLNFLLPTIFKSCSTFEQWFnapfamtgervdlneeetiliirrLHK 940  human
Q6DIC0        866 CKLTQVLNTHYvaPRRILLTGTPLQNKLpELWALLNFLLPTIFKSCSTFEQWFnapfamtgervdlneeetiliirrLHK 945  house mouse
NP_990470     857 CKLTQVLNTHYvaPRRILLTGTPLQNKLpELWALLNFLLPTIFKSCSTFEQWFnapfamtgervdlneeetiliirrLHK 936  chicken
XP_004910846  843 CKLTQVLNTHYvaPRRILLTGTPLQNKLpELWALLNFLLPTIFKSCSTFEQWFnapfamtgervdlneeetiliirrLHK 922  western clawe...
NP_001038240  863 CKLTQVLNTHYvaPRRLLLTGTPLQNKLpELWALLNFLLPTIFKSCSTFEQWFnapfamtgervdlneeetiliirrLHK 942  zebrafish

Feature 1                    
P51531        941 VLRPFLLRRLK 951  human
Q6DIC0        946 VLRPFLLRRLK 956  house mouse
NP_990470     937 VLRPFLLRRLK 947  chicken
XP_004910846  923 VLRPFLLRRLK 933  western clawed frog
NP_001038240  943 VLRPFLLRRLK 953  zebrafish

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