3D34,3Q13


Conserved Protein Domain Family
Spond_N

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pfam06468: Spond_N (this model, PSSM-Id:368927 is obsolete and has been replaced by 399462)
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Spondin_N
This conserved region is found at the in the N-terminal half of several Spondin proteins. Spondins are involved in patterning axonal growth trajectory through either inhibiting or promoting adhesion of embryonic nerve cells.
Statistics
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PSSM-Id: 368927
View PSSM: pfam06468
Aligned: 54 rows
Threshold Bit Score: 217.435
Threshold Setting Gi: 190589833
Created: 4-May-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3D34_A               15 AKYSITFTGKWSQTAFPKQYPLFR--PpaQWSSLLGAAHSSDYSMWRKNQYVSNGLRDFAERGEAWALMKEIEA--AGEa 90  human
OWR47220             23 AVYKVTVKFLWCETNFPKDYPLNQ--PkaQWSPLFGQSHNSSYHLYRVGEVASEAMRNFALFGKPEELLNQGDGd----- 95  Danaus p...
16_pfamImport         1 -VYKVIFKTFWSREKFPKHYPDWR--PlaQWSKLIGRSHNKSYTLWRLGSLASEGVKIFTETGKTDVLDAEAQGn----- 72 
ETN64481             46 vfYRIKLVTSWSKKLFPKHYPEFR--PppHWSMTFGQTHNASFRLYEMKQAASVPVATFAETGQIAPLEESLAQqqD--- 120 Anophele...
WGS:AAPP:GF13520-PB 156 AVYKVVLHTYWTRELFPKHYPDWR--PtaQWTKTLGRTHNANYALYHIGQPATAAVKQFAETGRTDLLDSNVGE--QQQq 231 Drosophi...
OWR42007              2 tVYRMVLHTYWTREKFPKHYPDWR--PpaQWSKVYGVSHSRSYVLFRLGRRVSPSVRQFAESGRSDTLGAAP-------- 71  Danaus p...
EFX74609              1 mVYKVTLATHWSRTLFPKQYPEWR--PpaQWSKVIGRSHDSSYTLFRISQASTEGFKEFTETGRSDTLDAQSQGe----- 73  common w...
EFX74998             15 tVYRVTLNTFWNPRNFPKHYPQWR--PpaQWSKLVGRSHNKSYTLYRLHQKATEGLKLFAENGRSDYLDTQSQGe----- 87  common w...
EEN64334             39 qKYTLVFEGLWSAKRFPKQYPIYR--PkaSWSSLVGVTHNDEYTLWHKGEIASEGVKLFAEKAGSFKLFSDFADs----- 111 Florida ...
XP_011670522         33 vTYELTFHGDWSQTAFPKQYPIYRknA--QWSPVLGAVHNSRFQMWKEGEVSSEPFSRFVQGADIKNLRPALTG--RST- 107 purple s...
3D34_A               91 l--------------------------------------qSVHEVFSAPAV-PSGTGQTSAELEVQRRHSLVSFVVRIVP 131 human
OWR47220             96 ---------------------------------------eRVYDQFLAPAVg-DGTGETGNIVFLDGEYSLISVACRLIP 135 Danaus p...
16_pfamImport        73 ---------------------------------------gGVYDEFMAAPIs-IGVGQTQAEFFVDGNHSKVSLMCHLHP 112
ETN64481            121 ----------------------------------------VLFDEFRLPKIr-KGKGASEATFFVDGQHSSVSFMTKIVP 159 Anophele...
WGS:AAPP:GF13520-PB 232 qmqaqaqaqiqmprqtgksplgatartatgpserssnnerSVFDEFSMPAIq-MGAGRSEAKVFVDSNHSLVSLMTRIVP 310 Drosophi...
OWR42007             72 ----------------------------------------GTLDVFGGAAIg-QGLGRAEADFFVDGNHSRVSVMTKMIP 110 Danaus p...
EFX74609             74 ---------------------------------------gGIFDEFNAPPVt-AGEGKTEAEFFVDSNHSRVSLASRIVP 113 common w...
EFX74998             88 ---------------------------------------gGIYDEFNAPPIt-SGEGKTEAEFFVDGNHSRVSLISKLVP 127 common w...
EEN64334            112 ---------------------------------------kGTSGKFFADEIkNKGVGERKTDFAIDADHSKVSFMVKIVP 152 Florida ...
XP_011670522        108 ----------------------------------------DVYTTFASDGV-PSGVGSTSIQFRMHREFTEVSFAVRIDP 146 purple s...
3D34_A              132 SPDWFVGVDSLDLCdGDRWREQAALDLYPYDAGTDSGFTFSSPNFATIPQDTVTEITSSSPSHPANSFYYP 202 human
OWR47220            136 SPDWFIGVDSLELCvDSSWVDQITLDLEPLDVGAASGLSFTAPHWESF--QPVSKHRPQQPSHPSAAFYYP 204 Danaus plexippus ...
16_pfamImport       113 SPDWFVGIDSFDLCvQGKWLDAVTLEVDPMDAGTDEGYTFTAPNWKSEPQEKIYRLTAQYPNNSANSFYYP 183
ETN64481            160 SPDWFVGLDSFNLCsRGRWIDRMTVPLHPLDAGTSSGLTFTSPKWPTNPPGMIEQITARYPLHFASSFFYP 230 Anopheles darlingi
WGS:AAPP:GF13520-PB 311 SPDWFIGVDSFELCvGGSWIDTVTVELDPLDAGTDNGFTFTAPNWPTAPQGVIYRITSRYPAHPAGSFYYP 381 Drosophila ananassae
OWR42007            111 SPDWFIGVDSFDLCvDGNWLDSITIEVDPLDAGTDNGFTFTAPNWPTAPQGVAYRITSKYPSHPAGSFFYP 181 Danaus plexippus ...
EFX74609            114 SPDWFVGLDSFNLCiDGQWVDSVAIKVGPMDGGTDNGFTFTSPNWPSDPTEKIFRITSNMPNHPANSFYYP 184 common water flea
EFX74998            128 SPDWFIGIDSLDLCvNSKWLDSISIEVGVVDAGTDNGFSFTSPNWPTEPQEMIRHLTSNFPNHPASAFFYP 198 common water flea
EEN64334            153 SPDWFVGLDSKDLCqNGKWIDQFSTRLGPWDAGTDKGFTFTSPNWATVPQEPVFQISSTFPNHPANSFYYP 223 Florida lancelet
XP_011670522        147 SPDWFVGQSSLDLCrSGEWLHDMTLDLYPFDAGTDQGFMFTSPDFPEVPRQPIVEITSRVPSHPANSFFYP 217 purple sea urchin
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