EDO16756 5 IVIFDPS--KSLTEDD-TYKELILYHSFqneeT--SLNDKLGKIGVLQSLWSFTETl-NGDSSSIeekiIELDDEIIIIY 78 Vanderwaltozyma pol... Q6FX38 16 VIVFRPGenKGEQEDSvVSEQLLLHHAFed-tEliTLSAKLGKIGIIQALWTLSED--TNDTCKI----IETEQETMITI 88 [Candida] glabrata ... Q7EY72 14 LCVFDLR--RGQQEGQ-ELDKILFFHPTd-----cPILLQLSVIGLCEGIITFARIfsPDDDCEV----IESEKHSHVFY 81 Japanese rice C0Z274 15 LCVFDLR--RGQHEGQ-ELDKILFFYPPd-----lTFSTQLSVIGLSEGLITFTRLfsPEAACEV----IEAERHSHVFY 82 thale cress OAP14269 13 LCMFDLR--RGQTEGQ-ELEKILFFYPAd-----lDFSTQLSVIGLSEGLITFTRLfsPEAACEV----IEAERHSHVFY 80 thale cress Q54IQ5 13 FVIYCSK--LGQKEGT-EHEKILFFYPPt-----iNIGEQTNSVGISEAYVLFTKQfsPGQPCEF----IHTKKSTLALL 80 Dictyostelium disco... A7RJI7 13 FFIFNST--YGPREGE-EHEKIILYIPTe-----eDIDRKIKTIGLCEALVKFTETfaPDKPCES----LHTQKSRQIFY 80 starlet sea anemone P86790 27 FFIYNPR--FGPREGQ-EENKILFYHPNe-----vEKNEKIRNVGLCEAIVQFTRTfsPSKPAKS----LHTQKNRQFFN 94 human Q16UQ0 15 FFVFNSS--FGPKEGE-EEKKILFYHPQe-----tDIDSKVKDVGLCEAIIQFSNTftNDNSVHA----MHTQKTCQLYH 82 yellow fever mosquito Q9VZL5 15 FYIFNST--FGQVEGE-EHKKVLFYHPNd-----iELNTKIKDVGLSEAIIRFTGTftSEDDCQA----LHTQKTTQLFY 82 fruit fly
EDO16756 79 KVENQFYLCLSVIlq-dEMDNIlfPHQL-----------YSCHLKYCYEFFILQFGEFNSFt--------NINQLTDSLN 138 Vanderwaltozyma pol... Q6FX38 89 KVEGEFYITLAIGv---DPDLLaiPNPI-----------FEGHLWNCYHFFTIKYGDFTSF---------EKHVLTDLLN 145 [Candida] glabrata ... Q7EY72 82 QAEADIWMVLVVE------KNKdiESTWrc-------gaLQGILKEVHSLFTMFHGPIRTLldrqpsaelARGHLRTFFT 148 Japanese rice C0Z274 83 EAEPDIWMVMIVE------KNKeiEAVWri-------daLRRVLKEVHSLFVMFQGSIRALlekeptgglVRSHLYPFIT 149 thale cress OAP14269 81 EAEPDIWMVMVVE------KNKetGAIWri-------daLRRVLKEVHSLFVMFHGSIRALiekeptgglTRSLLYPFIT 147 thale cress Q54IQ5 81 HPEEDIWMVLSVYnp-tGITGKdnK--ReyiedevddiiLMKTIQQIYQTWQTFNGSIMSLas-----ktSYDNVRKRLE 152 Dictyostelium disco... A7RJI7 81 QPEPDFWMIMTISipfsEKIAKdgKNTIeyhyddvldnvLDAVLKQSYKMFKLFNGPFNYLse-----tyGREALKKRSE 155 starlet sea anemone P86790 95 EPEENFWMVMVVRnpiiEKQSKdgKPVIeyqeeelldkvYSSVLRQCYSMYKLFNGTFLKAme-----dgGVKLLKERLE 169 human Q16UQ0 83 QPEPGYWMTMILNvp-fERKTRetGDYNeyhgddihdtiYQAVLKQSYRMFRLFHGSFASNlkpd-edldAVANLIGKLE 160 yellow fever mosquito Q9VZL5 83 QPEPGYWLVLVLNvp-kEVRLKegVEVAdyrgaeisdriYRAILRQCYQMFRFQNGCFSSCgseepnpdkRRELLCQKLL 161 fruit fly
EDO16756 139 EYLVLFW--NDIILKPETMKRKML-NCfypdsfkvselqsdknldsswesilnQNILLNTENYLGIRdvlvyhlpsnsgk 215 Vanderwaltozyma pol... Q6FX38 146 EHFVSFW--NDLYRKPESLTRNFL-QYlchdfykvadld--pngdkqweatiiQDLLVQTENYLGIKdilvynipst--- 217 [Candida] glabrata ... Q7EY72 149 DYLSDFNagKKIQLPTFRDCLKERgTV--------------------------QMLTISREVALEVQ------------- 189 Japanese rice C0Z274 150 DYLNDLFvgKKQQLPSFRDTLKERgTV--------------------------QMLTLARDAALEVQ------------- 190 thale cress OAP14269 148 DYLSKFFvgKKLQLPTFRETLRERgTV--------------------------QMLTLARDTAVEVQ------------- 188 thale cress Q54IQ5 153 SFVKPYI--QQIQ-FDQLDLFTSLdGI--------------------------KFLPLNKNVYLTIF------------- 190 Dictyostelium disco... A7RJI7 156 YFFLSYL--QTLN-FSSFDLLDIFaGI--------------------------QFLPLDKNTFLKIQ------------- 193 starlet sea anemone P86790 170 KFFHRYL--QTLH-LQSCDLLDIFgGI--------------------------SFFPLDKMTYLKIQ------------- 207 human Q16UQ0 161 EFYLKYI--LHLK-LKDCDVLDAFgSV--------------------------QYLPLNQLLFLRVQ------------- 198 yellow fever mosquito Q9VZL5 162 QFYDQHL--TNLRDPAQCDIIDMLhSI--------------------------QYLPLDKTLFLRAQ------------- 200 fruit fly
EDO16756 216 snngttnnsssnnfntkdyGFIRN----FATDLDSLPHISNWIHHLHTTYED-ISSHTlsgnahyketqienedsp---- 286 Vanderwaltozyma pol... Q6FX38 218 ---------estyvgkckyGLIRN----FCNEFEDLGHFSNWLQHIHTVFGK-ISSHVlaenvhyelhsgqleqtnsdgi 283 [Candida] glabrata ... Q7EY72 190 -------------------SLTTV----LGSCLGNVMCQSLVLFEDLLVSTT-LPPDD---------------------- 223 Japanese rice C0Z274 191 -------------------SLVGV----LDSCAGTVRCHSVILFHDLLVSTT-LSPDD---------------------- 224 thale cress OAP14269 189 -------------------SLVQV----LDSCAGSLRCHSMILFQDLLVSTT-LSADD---------------------- 222 thale cress Q54IQ5 191 -------------------GYINSvdlhFQSTLSSFR-FGLVLYKDNLILSS-LEQNE---------------------- 227 Dictyostelium disco... A7RJI7 194 -------------------SFVNL----IEHTFSQIK-YTAFLYSDKLVWSG-LEQED---------------------- 226 starlet sea anemone P86790 208 -------------------SFINR----MEESLNIVK-YTAFLYNDQLIWSG-LEQDD---------------------- 240 human Q16UQ0 199 -------------------NFINM----IEATFEPIK-HCVFLYDDFVIWSG-INPHD---------------------- 231 yellow fever mosquito Q9VZL5 201 -------------------NF-GT----LCETFPDIK-ESIMLYQEQVLCGGkLSPED---------------------- 233 fruit fly
EDO16756 287 ------eitnddqqndplsftdqtKNFLYNMTLPISFAYDVVQEVGESTGIGNSMSLVMNYIPK---------FSFSENS 351 Vanderwaltozyma pol... Q6FX38 284 rdgndlnlsdnnnetdsntfsqlsTNFMHNLTLPITFAYDAIQEVGNTTGINNSVSLFMNYLPKwq------nNSTASEN 357 [Candida] glabrata ... Q7EY72 224 ------------------------TLNLYTYAILRLTPRALLSNATSWSYLRKGTSVHAGPTSS---------------S 264 Japanese rice C0Z274 225 ------------------------TVDLFAFSVMRLTTNALSSGTSSWSYLRKGSGSPQISSRSttvpplgsgGTLPSGN 280 thale cress OAP14269 223 ------------------------TVDLFTFAVMRLTSKALSSDTSSWSYLRKGPGSSEISSRSnlap-vgsiDSLHSRN 277 thale cress Q54IQ5 228 ------------------------TRILYNYLINMVKVGPDINSSNSMIVKNNSNNIPIWQTKGv--------RTGFMIQ 275 Dictyostelium disco... A7RJI7 227 ------------------------MRILYKYLVTSLFPATIDSELAD----RSSQGYVVIQPKShhg----rfVTGPPDL 274 starlet sea anemone P86790 241 ------------------------MRILYKYLTTSLFPRHIEPELAG----RDSPIRAEMPGNLqhy---grfLTGPLNL 289 human Q16UQ0 232 ------------------------LYTLYEYLNGPMFQAVTGQEHSR--------------------------------- 254 yellow fever mosquito Q9VZL5 234 ------------------------LHCVHSYVVQHVLKVEASSSTI-----AVSPSLKRSISECqvg---gfvRSRQKVA 281 fruit fly
EDO16756 352 TNNKRQlngq-------efsERHGflispLANNSLPESYkikklrLKFkQYKESKVF-NTLFWYMNDTLLVLVFNDDFEN 423 Vanderwaltozyma pol... Q6FX38 358 EKNKTK--------------ARYGylispLAFDSLPKSYklkkmhLKF-NGEERKPY-HVLFWYYNDVLVVIICNESFDS 421 [Candida] glabrata ... Q7EY72 265 SNGTASverplqreklykgkDGFVaagstTSEVRGAVAW------VPIlWFQQAEDRmHLCVYQHKN-ITILLLIPASSL 337 Japanese rice C0Z274 281 GSSTGRvirplqhdkwskgkDGFL-----VTDIWGLDA-------TPTiLIQKTQESfYLLTYQYKS-LTLVLLVPIAAI 347 thale cress OAP14269 278 GNNMHHvirplqndkwtkgkDGFL-----ITDIWGLETGgspdsaIPTiWLQQTQERmYLLAYQHKS-LTLLLLMPTNAI 351 thale cress Q54IQ5 276 KDS--------------------------LPMVWL------------------GGKPqAMIVYEQKDTFLLFLIDPSDLP 311 Dictyostelium disco... A7RJI7 275 KDIPTPr---------------------kPPRIFV--------------NTDTEQEElLLICYKALD-ATICLLVSA--P 316 starlet sea anemone P86790 290 NDPDAKc---------------------rFPKIFV--------------NTDDTYEElHLIVYKAMS-AAVCFMIDA-SV 332 human Q16UQ0 255 -------------------------------KVYV--------------QENGQDKTyNFMVCRKVQNITLCLFLE--EV 287 yellow fever mosquito Q9VZL5 282 GDEHDAvne-----------------edhPMKVYV--------------TLDKEAKPyYLLIYRALH-ITLCLFLNADQV 329 fruit fly
EDO16756 424 IWDREYLKELDSKLYEAISFLYKS----INAAKS-SvkkVKSEPF------AYAVinkDDPGQIKIQTSIPSWFSSINNL 492 Vanderwaltozyma pol... Q6FX38 422 IWSKEYLNELNKHLENSIKTLYDQnlydLPNTDNhSnkkNDILNF------AYLI---TDKKRNKLYSSFPDLSWFNEQQ 492 [Candida] glabrata ... Q7EY72 338 INGDDGIAHVKRHLLENASQNIVTlelkLSRGWG-GenaYHVGGY------RYLL---VDPDRKVSRASPPGKVTTLSKD 407 Japanese rice C0Z274 348 VNGELDISFVKQQVIENASTKILKveekLSKGWG-GenaYHVSGY------RYLL---VDNDMEVSRASPPGKVATLAKE 417 thale cress OAP14269 352 VNGDLSISAVKQQVIEDASLRILKieenISRGWG-GenaYHIKGY------RYLV---VDNDTKVSRSSPSGKVTTLAKE 421 thale cress Q54IQ5 312 ---QLPFEDLSASLVQNFEFVNLTleqhYAKKAN------FDEQY------KYIY---FNQMNLAIRSPIKPKGP----- 368 Dictyostelium disco... A7RJI7 317 FPTLDFFKKLDMFIGPQLTTLANViceqSSKKSL-----SSDQQY------RYIY---FNHMNLAQKSTIHSKKASVA-- 380 starlet sea anemone P86790 333 HPTLDFCRRLDSIVGPQLTVLASDiceqFNINKR-MsgsEKEPQF------KFIY---FNHMNLAEKSTVHMRKTPSVSL 402 human Q16UQ0 288 ENEQALYHELNAVINPQLTSISSDitqhLAQQPS-PdgsKDDSAAt----pKFIY---FNELNLHYRGTIKLGTQKRNNP 359 yellow fever mosquito Q9VZL5 330 APKQDLYDDLHAYMAPQLTSLARDisseLTKEAV-GaagQDNSSGnsetapKYLF---INEQSLQHHTNFQR-----HLP 400 fruit fly
EDO16756 493 N-DV--NPLQLIvngvdqlfknttdfqtn---------nnfgldimgslfgynsKEDEISKnd------qeIIKNTNInf 554 Vanderwaltozyma pol... Q6FX38 493 E-TLyrTTLELVsngleqlrpqitanelsittidsnkqwgldimgnilsmlpsnSPVPVTKda-------sIPLMKKLnf 564 [Candida] glabrata ... Q7EY72 408 S-LLslNRLR--------------------------------------------EEIDLEKsrakrsdschDKDFEVC-- 440 Japanese rice C0Z274 418 S-LLalNKLR--------------------------------------------EEVDTEKnrs-----kqEKDMEIC-- 445 thale cress OAP14269 422 S-LLalNKLR--------------------------------------------EEVDSEKsra----kgqEKDMEIC-- 450 thale cress Q54IQ5 369 --ELnkETMKLL------------------------------------------NEIHADFeg--------gLSSEII-- 394 Dictyostelium disco... A7RJI7 381 --GVspEIMRLL------------------------------------------GDISAdfn-------sfQEDGETY-- 407 starlet sea anemone P86790 403 T-SVhpDLMKIL------------------------------------------GDINSdft-------rvDEDEEII-- 430 human Q16UQ0 360 SaAIpnDVMNLI------------------------------------------VDLLDDAkrngdddnttNATEETI-- 395 yellow fever mosquito Q9VZL5 401 Q-GLprNVLSII------------------------------------------ADLANGSgkae--mesaPA-EEVQ-- 432 fruit fly
EDO16756 555 lgqmddeklwelhlellqiisnvkisrklpdlneerLLKLSNGLLCYVKDNENETMLVIKNWfdinen--------ekpt 626 Vanderwaltozyma pol... Q6FX38 565 ldklnekvlrdisietl-raietlsqsinsniqeekLLKTSDGILLYIRNDCNNLTIILKNWiqdtkhqtralkyknhtl 643 [Candida] glabrata ... Q7EY72 441 ------------------------------------IRAKNNAWVIAKVTRGRELYMALEKA------------------ 466 Japanese rice C0Z274 446 ------------------------------------IRAKNNTWVIARLNRGKELYMALEKA------------------ 471 thale cress OAP14269 451 ------------------------------------IRAKNNVWVIARVTRGKELYMALEKG------------------ 476 thale cress Q54IQ5 395 ------------------------------------VKTQQDRWIVAKKIDFREFYIMFDNK------------------ 420 Dictyostelium disco... A7RJI7 408 ------------------------------------VKTMSDCWVVGRKSDQREFFVILNQK------------------ 433 starlet sea anemone P86790 431 ------------------------------------VKAMSDYWVVGKKSDRRELYVILNQK------------------ 456 human Q16UQ0 396 ------------------------------------LKTHDDYWIVKRSCNSRHVFIVLNK------------------- 420 yellow fever mosquito Q9VZL5 433 ------------------------------------VKTTNDYWIVKRRCNYRQYYVILCNS------------------ 458 fruit fly
EDO16756 627 kSTNS----STLFGSLGSTVTEWN-DKRE 650 Vanderwaltozyma polyspora DSM 70294 Q6FX38 644 nSYSTsiedSNLFKNLGPDVISWY-SEYK 671 [Candida] glabrata CBS 138 Q7EY72 467 -GETL----LYASTAIEKFSNRYC-EGAF 489 Japanese rice C0Z274 472 -SETL----LDATDSVQRFSNRYC-SGAF 494 thale cress OAP14269 477 -SDTL----LDTTDAVGRFSNRYC-SGAF 499 thale cress Q54IQ5 421 -NSSI----LEINEEVKNATTKFF-KFLF 443 Dictyostelium discoideum A7RJI7 434 -SANL----IEINEEVKKLSSCHF-NNIF 456 starlet sea anemone P86790 457 -NANL----IEVNEEVKKLCATQF-NNIF 479 human Q16UQ0 421 -SSTL----IDVSEETKRILDQNM-KGIF 443 yellow fever mosquito Q9VZL5 459 -KATL----LDVTQEARRIFEQELtDDVF 482 fruit fly
Jiyao W et al.(2023). "The conserved domain database in 2023.",