pfam08778: HIF-1a_CTAD (this model, PSSM-Id:370116 is obsolete and has been replaced by 430212)
HIF-1 alpha C terminal transactivation domain
Hypoxia inducible factor-1 alpha (HIF-1 alpha) is the regulatory subunit of the heterodimeric transcription factor HIF-1. It plays a key role in cellular response to low oxygen tension. This region corresponds to the C terminal transactivation domain.
Jiyao W et al.(2023). "The conserved domain database in 2023.",