1OMX


Conserved Protein Domain Family
Glyco_transf_64

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pfam09258: Glyco_transf_64 (this model, PSSM-Id:370389 is obsolete and has been replaced by 401264)
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Glycosyl transferase family 64 domain
Members of this family catalyze the transfer reaction of N-acetylglucosamine and N-acetylgalactosamine from the respective UDP-sugars to the non-reducing end of [glucuronic acid]beta 1-3[galactose]beta 1-O-naphthalenemethanol, an acceptor substrate analog of the natural common linker of various glycosylaminoglycans. They are also required for the biosynthesis of heparan-sulphate.
Statistics
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PSSM-Id: 370389
View PSSM: pfam09258
Aligned: 22 rows
Threshold Bit Score: 255.674
Threshold Setting Gi: 1002291796
Created: 3-May-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1OMX_A        30 FTLIMQT--YNRTDLLLRLLNHYQAVPSLHKVIVVWNNvgEKGPEEL-----------WNSLGPHpIPVIFKPQTANKMR 96  house mouse
Q9LY62        74 YTLLMNT--WKRYDLLKKSVSHYASCSRLDSIHIVWSE--PNPPSESlkeylhnvlkkKTRDGHE-VELRFDINKEDSLN 148 thale cress
Q9JKV7       412 FSAVIWV--GASGESLLKLIQEVAGSRHCAQILILWNS--EKLPP-------------DRWPETA-VPLTVIKGHRKV-S 472 house mouse
Q08C36        66 FTIIMQT--YNRTDVLLRLLNHYQAVPHLQCIIIVWNNp-GETPPRRl----------WDELGPHpVPVLFREQRVNRMR 132 zebrafish
Q28F88        60 FTLIMQT--YNRTDLLLKMLNHYQAMPGLSHVIVVWNNv-GQDTPQEl----------WESFGPHpVPVTFKKQKVNLMR 126 tropical clawed...
Q3TSR0        53 FTLIMQT--YNRTDLLLRLLNHYQAVPSLHKVIVVWNNv-GEKGPEEl----------WNSLGPHpIPVIFKPQTANKMR 119 house mouse
Q9C975        48 ITVLINGysEYRIPLLQTIVASYSSSSIVSSILVLWGN--PSTPDQLldql----yqnLTQYSPGsASISLIQQSSSSLN 121 thale cress
Q84WB7       518 FTLATMTy-DARLWNLKMYVKRYSRCPSVKEIVVIWNK---GPPPDL-----------SELDSA--VPVRIRVQKQNSLN 580 thale cress
XP_015650243  49 LTVLLSGysERRLPLLRAIAGAYAAHPLVLAVVVLWSN--PSTPDSL--------------LSSFpPAVTLHRTASASLN 112 Japanese rice
NP_001125331 383 FSALIWV--APPGQPPLKLIQAVAGSQHCAQILVLWSN--ERPLP-------------SRWPETA-VPLTVIDGHRKV-S 443 Sumatran orangutan
1OMX_A        97 NRLQVFPEVETNAVLMVDDDTLISAQDLVFAFSIWQ--QFPDQIIGFVPRKHV-ST---SSGIYSYGGfelqtpgpgNGD 170 house mouse
Q9LY62       149 NRFKEIKDLKTDAVFSIDDDIIFPCHTVDFAFNVWE--SAPDTMVGFVPRVHWpEKsndKANYYTYSGwws----vwWSG 222 thale cress
Q9JKV7       473 NRFFPYSNISTNVILSLDAQSTLSTSEVDFAFVVWQ--SFPERMVGFLSGSHF-WDe--AQGGWGYRTg--------MTN 539 house mouse
Q08C36       133 NRLMMHPDVKTDAVLMLDDDILLSVPDISFAFSVWK--QFPDQIVGFVPRKHV-SS---ASGVYSYGSfelqdpdkgGGD 206 zebrafish
Q28F88       127 NRLQSFPEIQTQAVLMMDDDTLVSAYDISFAFSIWQ--QFPDRIVGFVPRKHV-SS---PSGIYSYGSfelkaphteTGD 200 tropical clawed...
Q3TSR0       120 NRLQVFPEVETNAVLMVDDDTLISAQDLVFAFSIWQ--QFPDQIIGFVPRKHV-ST---SSGIYSYGGfelqtpgpgNGD 193 house mouse
Q9C975       122 ARFLPRSSVDTRAVLICDDDVEIDQRSLEFAFSVWK--SNPDRLVGTFVRSHG-FDl--QGKEWIYTV---------HPD 187 thale cress
Q84WB7       581 NRFEIDPLIKTRAVLELDDDIMMPCDDIEKGFRVWR--EHPERLVGFYPRF--------VDQTMTYSAekf----arSHK 646 thale cress
XP_015650243 113 SRFLPHPSIRTAAVAVADDDVLPDAAALSFAFAAWQqrARPGTLVGFFPRSHH-LDl--ARGRWAYGAaa------rQQA 183 Japanese rice
NP_001125331 444 DRFYPYSTIRTDAILSLDARSSLSTSEVDFAFLVWQ--SFPERMVGFLTLSHF-WDe--AHGGWGYTAe--------RTN 510 Sumatran orangutan
1OMX_A       171 QYSMVLIGASFFNSKY-LELFQ---K-QPAAVHALIDETQNCDDIAMNFLVTRHTGKPSgi-fVKPInmvnlekETN-G- 242 house mouse
Q9LY62       223 TYSMVLSKAAFFHKKY-LSLYT---NsMPASIREFTTKNRNCEDIAMSFLIANATNAPA----IWVK-------GKIyEi 287 thale cress
Q9JKV7       540 EFSMVLTTAAFYHRYY-HTLFT---HsLPKALRTIADETPTCVDVLMNFLVATVTKLPP----IKVPygrqhpeAVPmDs 611 house mouse
Q08C36       207 RYSMILVGASFFHRRF-LKQFQ---E-QPAEVHTLLDRTQNCDDIAMNFIVARQLSKRPsgvfVKPVhmsnlekDASsG- 280 zebrafish
Q28F88       201 MYSMILIGAAFFHSDY-LRLFE---Q-LPASVHNMIDQTQNCDDIAMNFMVANHLGKASgv-lVKPTdmrnlekEAGsG- 273 tropical clawed...
Q3TSR0       194 QYSMVLIGASFFNSKY-LELFQ---K-QPAAVHALIDETQNCDDIAMNFLVTRHTGKPSgi-fVKPInmvnlekETNg-- 265 house mouse
Q9C975       188 KYSIVLTKFMMMKQDY-LFEYSckgGvEMEEMRMIVDQMRNCEDILMNFVAADRLRAGPi--mVGAErvrdwgdARNeEv 264 thale cress
Q84WB7       647 GYNMILTGAAFMDVRFaFDMYQ---SdKAKLGRVFVDEQFNCEDILLNFLYANASGSGKaveyVRPSlvt-idtSKFsG- 721 thale cress
XP_015650243 184 RYSMVLTKLLVLGAGL-LREYSc--SpELAAARAVVDRERNCEDILMNFVAAEESGEGPv--lVEAGsirdwgdPRNdDa 258 Japanese rice
NP_001125331 511 EFSMVLTTAAFYHRYY-HTLFT---HsLPKALRTLADEAPTCVDVLMNFIVAAVTKLPP----IKVPygkqrqeAAPlAp 582 Sumatran orangutan
1OMX_A       243 ------------YSGMWHRAE--HFLQRSYCINKLVNIYDGMPLKYSNIMI--S 280 house mouse
Q9LY62       288 -----------gSTGISSIGG--HTEKRTHCVNRFVAEFGKMPLVYTSMKAvdS 328 thale cress
Q9JKV7       612 -----------gDPRPVPEPQ----PLDQDCINRLAAGFGHMPLVSSQVRL--D 648 house mouse
Q08C36       281 ------------FVGMWHRPE--HMLQRSYCLNKLAQIYGHMPLRYSNIMI--T 318 zebrafish
Q28F88       274 ------------YTGMWHRAE--HLLQRSFCLNKLAEIYSTMPLKYSSIMI--S 311 tropical clawed frog
Q3TSR0       266 ------------YSGMWHRAE--HFLQRSYCINKLVNIYDGMPLKYSNIMI--S 303 house mouse
Q9C975       265 ee-------rvrDVGLSSRRVe-HRKRRGNCIREFHRVMGKMPLMYSYGKVv-N 309 thale cress
Q84WB7       722 -------------VAISGNTNq-HYRKRSKCLRRFSDLYG--SLVDRRWEFggR 759 thale cress
XP_015650243 259 dagagaggeemkAVGLSSTGGaaHWEKRGDCITEFHRLLGRMPLRYSYGKVvaa 312 Japanese rice
NP_001125331 583 -----------gGPGPRSKPQ----APAPDCINQIAAAFGHMPLLSSCLRL--D 619 Sumatran orangutan
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