3JBR


Conserved Protein Domain Family
VGCC_beta4Aa_N
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pfam12052: VGCC_beta4Aa_N (this model, PSSM-Id:371868 is obsolete and has been replaced by 463445)
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Voltage gated calcium channel subunit beta domain 4Aa N terminal
The beta subunit of voltage gated calcium channels is coded for by four genes 1-4. Gene 4 can produce two types of beta4A domain (beta4Aa and beta4Ab) according to how the gene splicing is carried out. This family is part of the beta4Aa N terminal domain. It is made up of an alpha helix and a beta strand. It is thought to regulate the channel properties through protein-protein interactions with non Ca channel proteins.
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Statistics
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PSSM-Id: 371868
Aligned: 14 rows
Threshold Bit Score: 57.9021
Created: 13-May-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3JBR_B         4 GSADSYTSRPSd-SDVSLEE-DREAVRREAERQAQAQLEKAKTK 45  Norway rat
ESO05123      15 GSFESNCSQNS--SNLSLEE-EQESIRKNAEKLAQTMLEKARTK 55  Helobdella robusta
EEC14293       9 GSADSNYSQPS--SDLSLDE-DRENTRRETERLALAKLQSAREK 49  black-legged tick
EGT32535       7 GSGDSNFSHHD---ELELEAgNRETLRRDAERQAALQLERAKYK 47  Caenorhabditis brenneri
PNI85963      16 GSADSYTSRPSd-SDVSLEE-DREAIRQEREQQAAIQLERAKSK 57  chimpanzee
XP_012811902  14 GSADSYTSRPSldSDVSLEE-DRETARREVERQAQEQLERARLK 56  tropical clawed frog
XP_028035687  24 GSAESNCSQPS--SELSLDD-DKEALRREKEAQALSQLDKARSK 64  wild silkworm
XP_005991485  16 GSADSCTSRPSldSDVSLEE-DREVVRRDAEQHALLQLERAKSK 58  coelacanth
AAC19386      50 GSAESYTSRPSd-SDVSLEE-DREALRKEAERQALAQLEKAKTK 91  house mouse
XP_016306102  16 GSADSYTSRPSd-SDVSLDE-E-QGGRQEKEQQATIQLERAKAK 56  Sinocyclocheilus anshuiensis
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