pfam12460: MMS19_C (this model, PSSM-Id:372125 is obsolete and has been replaced by 463594)
RNAPII transcription regulator C-terminal
MMS19 is required for both nucleotide excision repair (NER) and RNA polymerase II (RNAP II) transcription. This C-terminal domain, along with the N-terminal, MMS19_N, form part of a silencing complex in fission yeast that contains Dos2, Rik1, Mms19 and Cdc20 (the catalytic subunit of DNA polymerase-epsilon). This complex regulates RNA polymerase II (RNA Pol II) activity in heterochromatin and is required for DNA replication and heterochromatin assembly.
Jiyao W et al.(2023). "The conserved domain database in 2023.",