Conserved Protein Domain Family
Defensin_big

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pfam14862: Defensin_big 
Big defensin
Big defensins are antimicrobial peptides. They consist of a hydrophobic N-terminal half, which is active against Gram-positive bacteria, and a cationic C-terminal half, which is active against Gram-negative bacteria. The C-terminal half adopts a beta-defensin-like structure.
Statistics
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PSSM-Id: 373348
Aligned: 5 rows
Threshold Bit Score: 47.6183
Threshold Setting Gi: 321460503
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EKC19784  75 MTVGAPLFLALVAAYGIYAVTRYAIKkaer----------------vsdkDNHACGRGIGWCRPKcfpgehldwddpllC 138 Pacific oyster
EEP75553   1 MKFSGYLCVLFGAVFVAAAPVTQADN------------------------DTPTPGKDREFCKAK--------------C 42  Uncinocarpus reesii...
Q8K3I8     1 MR----LALLLLAILVATELVVSGKN------------------------PILQCMGNRGFCRSS--------------C 38  house mouse
Q32ZG8     1 MK----LVLLLLAIFVTTELVMSGKN------------------------PTLQCMGNRGFCRPS--------------C 38  Norway rat
EFX71545  66 LKVAPSIYRWMNGLYGGAAVTRIGVTvaegpspslerrvpccsgyltptmDARNCTKMGGEC-----------------C 128 common water flea
EKC19784 139 GSY------YCCMP 146 Pacific oyster
EEP75553  43 KKDhaemveYCKTL 56  Uncinocarpus reesii 1704
Q8K3I8    39 KKSeqa-yfYCRTF 51  house mouse
Q32ZG8    39 KKGeqa-yfYCRTY 51  Norway rat
EFX71545 129 SRE------FTDYP 136 common water flea
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