6H6N


Conserved Protein Domain Family
SCP2
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pfam02036: SCP2 (this model, PSSM-Id:376720 is obsolete and has been replaced by 460423)
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SCP-2 sterol transfer family
This domain is involved in binding sterols. It is found in the SCP2 protein, as well as the C-terminus of the enzyme estradiol 17 beta-dehydrogenase EC:1.1.1.62. The UNC-24 protein contains an SPFH domain pfam01145.
Links
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Statistics
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PSSM-Id: 376720
Aligned: 123 rows
Threshold Bit Score: 50.6916
Created: 30-Apr-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6H6N_A             26 LNTFLYRs--------pALKTARSRLLGk------VLRVEVKGFST---SLILVFS---ER-QVDVl----gEWA-GDAD 79  Escherichi...
O28595             82 LQKLGLSldedmdvdslNYDELTKKVAE----------IKLDEVKGaalYIWLDFW---HG-EMRHaep-vaPGEkEDAK 146 Archaeoglo...
jgi:HY04AAS1_0102  10 IKAYKDQwnk-----neKLKNDLKNFSA-------KLKYYIISKENe--AVELIIK---NGeAISCg----mADG-KDYD 67  Hydrogenob...
O66500             15 IKAYAEEwnk-----neKLMNDLKNFSA-------SIKYYVEGKEN----DAVELI---IE-KGKAvsa-gkADPnKRYD 73  Aquifex ae...
jgi:Mvan_0494      12 araYRDLwnd-----saEIRQGAKELSM-------LIEWRVQDANDq--VSQLEIT---DG-EAIYgg---vQIQgRKPD 70  Mycoliciba...
jgi:HY04AAS1_0557  42 LVGMASSss-------eWRGAPVRKLFL--------YRKDCSPRKQi--ELYIQNM---NG-KAECiyggwaKDGrTGND 100 Hydrogenob...
O66445             26 AKQFCEVwnnt--pelvEKLGKSESWTEvperklfLYRKDCGPEKQ----IQLTIKnenGR-AVCVygg-wkKDEkTDND 97  Aquifex ae...
Q8CI66            296 LTALQPFl----------sEALVSQVGA-------CYQFNVILPSGtqsIYFLDLT---TG-QGRVghg-epDG---IPD 350 house mouse
O28738              8 IKKMCDLqns-----neEIQKEMAGWSG-------VVQYKLDGE-----EFYVEYKs--DG-TCEFkeg-vhS----SPT 62  Archaeoglo...
Q05DX0             11 FEELFGKa--------kESLPEIQSWNK-------VYQIVLEDDg----EFYIEIS---GG-ELKIadg-rhP----SPI 62  Aeropyrum ...

6H6N_A             80 CTVIAYASVLPKLRDRQ-QLTALIRSGELEVQGDIQVVQNFVALAD 124 Escherichia coli K-12
O28595            147 FKLSGPYAAFKEMIFKKiDPTTMIMQGKLKLQGDLAYMMRNIATVR 192 Archaeoglobus fulgidus
jgi:HY04AAS1_0102  68 FEMWATLEDWKSLATGQmGPKAAMLTKKLKFKGSMITAMKYMGAFE 113 Hydrogenobaculum sp. Y04AAS1
O66500             74 FELWASLENWKKLATGEmGPRAAMLTKRLKFKGSMITAMKYMGAFE 119 Aquifex aeolicus
jgi:Mvan_0494      71 FVLTATASVWHRVADGElGVANAIATRKIKFVGPVKVAMANMAVLg 116 Mycolicibacterium vanbaalenii PYR-1
jgi:HY04AAS1_0557 101 FLMYATTKHWIEMGRGEyGPMHAMMFGELSFSGPKFVAMANMGPFS 146 Hydrogenobaculum sp. Y04AAS1
O66445             98 FLMYADTKRWLEMGRKEyGPMKAMLFGRLKFEGPRFVAMKNMGPFE 143 Aquifex aeolicus
Q8CI66            351 VVVEMAEADLQALLSKElRPLGAYMSGRLKVKGDLAVVMKLEAVLK 396 house mouse
O28738             63 FTVVAPPDFWLAVLKGQeDPVSGFMMGKYRIEGNIMEAQRLAGVIK 108 Archaeoglobus fulgidus
Q05DX0             63 ATLTLTSDTLKEILEGQtDAMKAFMMRKLKITGNVLDTMNLKRIID 108 Aeropyrum pernix
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