Conserved Protein Domain Family
CHAT
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pfam12770: CHAT (this model, PSSM-Id:378942 is obsolete and has been replaced by 432771)
CHAT domain
These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.
Links
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Statistics
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PSSM-Id: 378942
Aligned: 53 rows
Threshold Bit Score: 94.7524
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_001564735  1053 QEPLRVLYQACIH-P-------IIGyvralDSQLLFgdgMITVVPSG------QMWLVPFHA--LLNVKAg--dRYFVEE 1114 Leishmania b...
Q113D1         130 NSQAKKIRGWLLKlq-----ekL---------QERQhnfSYLIINDR------TTFEIPWEMleLKNN------DYLGAS 183  Trichodesmiu...
Q8DHI1          67 GASGNQITNIGTQqPnll----------keVRHTYE---NLVISLGT------WLNRTRINF--LSEAQLneqsAFSREQ 125  Synechococcu...
Q5LLA3         680 RIFGELLFETLLP-QevrrlydV---------ARSRehdKLFVIFTSmi---hWVFDMPWEF--ARDPERg---TYLATE 741  Ruegeria pom...
Q112V9          62 TKVGEALFEALFD-AqlreyflAYYqdilkQQDA-----NLGIILEIneeampEVVAYPWELmcLPEKYNqg-qIYFATN 134  Trichodesmiu...
WP_011744668    43 KPIGSALWSALGDgVelq----------qaKHQAGQsilPIVIESDIp-----AILQLPWEM--LWHPEY----GFLALH 101  Chlorobium p...
WP_011744671    46 QALGSALWQVLDAdEklq----------haKKQAGTgilPLVIASDDp-----AILQLPWET--LYHPDY----GFLARH 104  Chlorobium p...
Q3AQG5          44 QAIGSILWRLLDAdEala----------naKQRAGQhivPLLLSSNDa-----AIQQLPWET--IYHPDY----GFLARH 102  Chlorobium c...
WP_012256484    54 TRYGQELFRRLFP-TrlshqfrVSQrtaaqQQQPLRl--RLALDPQDa-----ELQAIPWELlhFPATDNqsqlIPLTTS 125  Chloroflexus...
jgi:Caur_2874   60 VAYGTALGTMLLSdPdllaqfqAARaiarrGRRPLPirfRLFIAPSAa-----ELHALRWETlcMPDG------EPLLMG 128  Chloroflexus...

XP_001564735  1115 ---AAVQ--MAFS---ATQAAFAALSAVRVQQqdlhrevvAVQGDADHD----AAdtlfCTAFP--PNTDRSEQEgAAVV 1180 Leishmania b...
Q113D1         184 ----------------LVTVRWQDITNPEDLDnvngfinlEVTEKKCCG----KIv---AYLNT--KDLPEVEQE-KEII 237  Trichodesmiu...
Q8DHI1         126 asfFGLGnfILPPp--ISEIHRISVQTDFVQLwrypwhdwTPIRQHSNL-----Dvv-fSPMVYqsLKSPAAQHErVRIL 197  Synechococcu...
Q5LLA3         742 ----DVH--FIRNv--LTQTPVEKLSPRES-Lki-----lIATSEPRDQ----RR-----------VSATEEIAKlRKAI 792  Ruegeria pom...
Q112V9         135 ---RKLS--FYRRryqLEESNKLSIKINQDEQlk----iaLVVSKPTAD-----------------SGLSDVEYYeVHKY 188  Trichodesmiu...
WP_011744668   102 ---KEFT---------LSRS-SPAIKVHMPDIetgplrilLFSSLPDDLdetdQ------------LQIEEEQAGvLEAL 156  Chlorobium p...
WP_011744671   105 ---EGFT---------LSRT-IPSIKTGVSDIepgplrilLFSSLPDNLgeknQ------------LEIEVEQGRvLEAL 159  Chlorobium p...
Q3AQG5         103 ---EGFT---------FSRT-IPSVQKALPDAakgplrilLFSSLPDDLtekeQ------------LQIEVEQAAvLEAL 157  Chlorobium c...
WP_012256484   126 ---DQIL---------FSRYIDSEQFALFEPIdhhpirllLIFSEPTDL----DR----WQLSP--FDRPATERDfRQRF 183  Chloroflexus...
jgi:Caur_2874  129 ---EEVY---------FSRYLTSNDVQPIRARsrnalrvlIAIANPHGI-----------------ERFGLAPVDvAGEL 179  Chloroflexus...

XP_001564735  1181 AMLsagqvqlaewlgrHSTPEK-------VVTRKVELveNVESLRTVL----------PRARTVHIATATTSAaplsqag 1243 Leishmania b...
Q113D1         238 EVFhst-------iydN------------VRNFFDDL--DKVNLDQVN----------SEVSLVFIASHGFFD------- 279  Trichodesmiu...
Q8DHI1         198 AIF-------------GASGNLdlegdleALRALPDG--ELHCLRSPQlsely-slwsQPWDILFFAGHSQGK------- 254  Synechococcu...
Q5LLA3         793 TEL-------------QRDGLI-------EFEIRKNA--TPRNLHHEIa--------tGNYDVVHFIGHGYWN------- 835  Ruegeria pom...
Q112V9         189 LKS-------------IDTKQEqv----kFLPVMNSL--DFYSIVERLe--------tEKPDIFHFIGHGQLVe------ 235  Trichodesmiu...
WP_011744668   157 GPW-------------LQSGHV-------VIEMPDDG--RFSLFEELLh--------sFRPHLVWLSGHGVFSkd----- 201  Chlorobium p...
WP_011744671   160 GQW-------------RQSGHV-------VLEMPDDG--RFSEFKRILk--------sFKPHLVWLSGHGIFQsd----- 204  Chlorobium p...
Q3AQG5         158 GEW-------------RQSGHV-------VLEMPDDG--RFSEFTQVLk--------sFKPHVVYLSGHGMFQhd----- 202  Chlorobium c...
WP_012256484   184 RPF-------------VDTGQL-------KFDILPRA--EEAELRLALergslqteeaRGYDVVLYFGHALFL------- 234  Chloroflexus...
jgi:Caur_2874  180 AR--------------ARAGFAhf----dIVELVEPGaaTLEQIISTLrtsa---rkgQPFDVLYVVAHGSFV------- 231  Chloroflexus...

XP_001564735  1244 pvdrtaSRPEDEGGLLMRTAARMgDIGLVRAAEIAH--MGLA------AEHVILTNTNMS----------PQHMDg---- 1301 Leishmania b...
Q113D1         280 -------KDLSQSKLGEKD-----ETQQISVYDLYEydFNFFk----kGSIVFMNACNSGrlqqndtlkiIDTNPt---- 339  Trichodesmiu...
Q8DHI1         255 -------------GITINN-----EEPPLEIYRLYE---TLKtavkqgLQLAIFNSCDSI-------------------- 293  Synechococcu...
Q5LLA3         836 -------TKSGESGLVLEDETG--NSRPLGGRPLRE---ILSgr---gIRLVFLNACDTG-------------RSrrasg 887  Ruegeria pom...
Q112V9         236 ------KNGEDLGQVAFVNEFG--EADWKDAKMFCQ---LFTgh---qPKVVILQACETG--------------Kq---- 283  Trichodesmiu...
WP_011744668   202 -----lLNHNHKGYFLFEDEESG-NGSLVDENTLAG---AFSgt---aVQGVILSACQSG--------------Ka---- 251  Chlorobium p...
WP_011744671   205 -----pLNHHDKGYFLFENEHGD-GGELVDEDQLAE---AFTgi---dLQGIILSACQTG--------------Ka---- 254  Chlorobium p...
Q3AQG5         203 -----aLNHTTTGYFFFEDEVSG-KSKAFSEAEIAA---ALTat---aVQAVIVSACESG--------------Ka---- 252  Chlorobium c...
WP_012256484   235 --------PERGTRLLLEHGPQR-RGRLFDGEELIRllTQLPat--hkPAMIALIACNSA-------------------- 283  Chloroflexus...
jgi:Caur_2874  232 ---------EGNTYLWLVKPDN--TFDRVDGSSFCQ---RLRela-erPRLVMLIACQSG----------GGMTT----- 281  Chloroflexus...

XP_001564735  1302 -IRDDVLR----LVRGFFGSGVPCVIAGQWCTPDMKPIELFRHFYEQWCR--ALRTSQAEPSVHVVAATGDCVSpssaqp 1374 Leishmania b...
Q113D1         340 iGQEYPIG----FSTFFLEKGAEGVIGTLCEVYDTYAAKISRNFFQECQKypHLSVATILKNLRRKAADEYQRQ------ 409  Trichodesmiu...
Q8DHI1         294 -------P----LGQFLIQLGLPHAIVMREAVPNIAAELFLKYFLQNFQG--GADLYAAVAQARSQLRELSRCDdhlpgt 360  Synechococcu...
Q5LLA3         888 vETTSLAG----VAQDLFGRGVPNVVANQFPVGDNAAVAFARTIYEYLAH--GKTIAQSVREARISANYEK--------- 952  Ruegeria pom...
Q112V9         284 sETNAFSS----LASRLMLEGIPVVIAMQYKVSNQTAIIFVKEFYSKIID--GNSVEMAVQKARFKLRIEKGYEardfa- 356  Trichodesmiu...
WP_011744668   252 iSSDLNNG----LMYALAQKGIPHVIGMRESIFDRAGVQFAKTFFSGLLQ--KREIAQALQQARQAITMPMRDDehakry 325  Chlorobium p...
WP_011744671   255 dSANLNNG----LMYKLAWKGVPHVIGMRESILDRAGVQFAQAFFEALID--KKGIALALQEARRAIILPLKDDeearts 328  Chlorobium p...
Q3AQG5         253 aSDSLVNG----LTYRLLQQGIPHVIGMRESILDRAGIQFAQAFFSALME--RHGIAEALQQARNAIVLPLQEDeefkdt 326  Chlorobium c...
WP_012256484   284 -TVDLHAPlsnlAARLIAESGIPAVLAMQRLVAIELARTFTQHLTEMLLR--NGIVDLAVTTARRRIYRTDSIHwstpvl 360  Chloroflexus...
jgi:Caur_2874  282 -DNGALAA----IGPRLAEAGVPAVVAMQGNVSMRLIERFIPAFCQELQH--HGMIDAAMAVARGTV------------- 341  Chloroflexus...

XP_001564735  1375 tgalqpqrivgeegpeedgemvrhralllarsirhllveepAMRYRPRVW-----------AGY--YCIGS 1432 Leishmania braziliens...
Q113D1         410 -----------------------------------------KGNDENKYLf---------iYTFmyIYYGN 430  Trichodesmium erythra...
Q8DHI1         361 s---------------------------------alplicrHPQARCLHWhhlr----rsdTSPatVSVGD 394  Synechococcus elongatus
Q5LLA3         953 -------------------------------------------DGQSMDWai--------pVAY--ARDPE 970  Ruegeria pomeroyi
Q112V9         357 ------------------------------------ipvvfMNALDGYLFakesmeitqkkNGFl-SLTGE 390  Trichodesmium erythra...
WP_011744668   326 ryadls-----------------------fgqwclpmllsrEHNRSIIDW------------HFmpQPMGA 361  Chlorobium phaeobacte...
WP_011744671   329 ldaels-----------------------lgqwclpmllsrEHNRPIIDW------------HFtpQPMRA 364  Chlorobium phaeobacte...
Q3AQG5         327 veasis-----------------------lgqwclpmlfshQYNRALLDW------------EFtpQPMRA 362  Chlorobium chlorochro...
WP_012256484   361 ytrlasgr-------------------lfqpsellryiewlLQQDNIQRW------------------AGT 394  Chloroflexus aurantiacus
jgi:Caur_2874  342 -------------------------------------------RDLPDFWm---------pALYsrLKSGR 360  Chloroflexus aurantia...
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