?cl28903: BACK Superfamily (this model, PSSM-Id:391941 is obsolete and has been replaced by 475122)
BACK (BTB and C-terminal Kelch) domain The BACK domain is found in architectures C-terminal to a BTB domain, in a diverse set of architectures together with Kelch, MATH, and/or TAZ domains. It is involved in interactions with the Cullin3 (Cul3) ubiquitin ligase complex, as well as in homo-oligomerization. Most proteins containing the BACK domain are understood to function as adaptor proteins that play a role in ubiquitination of various substrates. |
Jiyao W et al.(2023). "The conserved domain database in 2023.",