1RN7,1DVC,1EQK,2W9P,1A67


Conserved Protein Domain Family
Cystatin

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pfam00031: Cystatin 
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Cystatin domain
Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but members have not been included.
Statistics
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PSSM-Id: 394988
View PSSM: pfam00031
Aligned: 34 rows
Threshold Bit Score: 56.1908
Threshold Setting Gi: 118187
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1RN7_A  12 GGIHATDLNDKSVQRALDFAISEYNKVInkdEYYSRPLQVMAAYQQIVGGV-NYYFNVKFGRTTCTk-SQPNLDNCPFNd 89  human
P32766  35 FGSINISN--ANVKQCVWFAMKEYNKESe-dKYVFLVDKILHAKLQITDRM-EYQIDVQISRSNCKk-PLNNTENCIPQk 109 house mouse
1A67_A   1 GAPVPVDENDEGLQRALQFAMAEYNRASn-dKYSSRVVRVISAKRQLVSGI-KYILQVEIGRTTCPk-SSGDLQSCEFHd 77  chicken
P01035  40 GGLMEADVNEEGVQEALSFAVSEFNKRSn-dAYQSRVVRVVRARKQVVSGM-NYFLDVELGRTTCTk-SQANLDSCPFHn 116 cattle
P19313  32 GGIEKSSMEEEGASEALNYAVNEYNEKNs-dLYLSRVVEVKDVQKQVVAGT-KFFFDVILGKTICLk-TQGDLTNCPLNe 108 Norway rat
P29699 150 PLLTPFND--TNVVHTVNTALAAFNTQNn--GTYFKLVEISRAQNVPLPVS--TLVEFVIAATDCTakEVTDPAKCNLLa 223 house mouse
P12763 150 PLLAPLND--SRVVHAVEVALATFNAESn--GSYLQLVEISRAQFVPLPVS--VSVEFAVAATDCIakEVVDPTKCNLLa 223 cattle
P29700 147 PLLAPLND--SRVVHAAESALAAFNAQSn--GSYLQLVEISRAQLVPLSAS--VSVEFAVAVTDCVakEAYSPTKCNLLv 220 pig
P01042  23 SEEIDCND--KDLFKAVDAALKKYNSQNq-sNNQFVLYRITEA-TKTVGSDtFYSFKYEIKEGDCPvqSGKTWQDCEYKd 98  human
P01044  22 SQEIDCND--QDVFKAVDAALTKYNSENk-sGNQFVLYRITEV-ARMDNPDtFYSLKYQIKEGDCPfqSNKTWQDCDYKd 97  cattle
1RN7_A  90 qpkLKEEEFCSFQINEVPW 108 human
P32766 110 kpeLEKKMSCSFLVGALPW 128 house mouse
1A67_A  78 epeMAKYTTCTFVVYSIPW 96  chicken
P01035 117 qphLKREKLCSFQVYVVPW 135 cattle
P19313 109 eadQQEHEFCSFVVHDIPW 127 Norway rat
P29699 224 ---EKQHGFCKANLMHNLG 239 house mouse
P12763 224 ---EKQYGFCKGSVIQKAL 239 cattle
P29700 221 ---EKQYGFCKGTVTAKVN 236 pig
P01042  99 a-aKAATGECTATVGKRSS 116 human
P01044  98 s-aQAATGECTATVAKRGN 115 cattle
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