4JA4_A 13 ITLVATLGG-LLFGYDTAVISGTVESLNtvfVAPQNLSESaANsl----------------lgFCVASALIGCIIGGALG 75 Escherichia coli K-12 P0C0L7 25 KAITAASLGnAMEWFDFGVYGFVAYALGkvfFPGADPSVQmVAa------------------lATFSVPFLIRPLGGLFF 86 Escherichia coli K-12 P36035 125 VNPIPELRKmTWQNWNYFFMGYFAWLSAawaFFCVSVSVApLAelydrp---------tkditWGLGLVLFVRSAGAVIF 195 Saccharomyces cerevis... P38142 27 GTIVACLGS-IQYGYHIAELNAPQEFLScsrFEAPDENISyDDtwvgqhglkqcialtdsqygAITSIFSIGGLFGSYYA 105 Saccharomyces cerevis... P22732 20 ATLIAAFGSsFQYGYNVAAVNSPALLMQqfyNETYYGRTGeFMedfpl----------tllwsVTVSMFPFGGFIGSLLV 89 human P28568 14 AVSVAAIGS-LQFGYNTGVINAPEKIIQafyNRTLSQRSGeTIspell----------tslwsLSVAIFSVGGMIGSFSV 82 chicken P38156 102 WSLLVSTTL-IQEGYDTAILGAFYALPVfqkKYGSLNSNTgDYeisv------------swqiGLCLCYMAGEIVGLQMT 168 Saccharomyces cerevis... P15325 24 LAAVASFTS-CMIGYDSAFIGTTLSLQSfqnEFNWESLNTdLIs------------------aNIVSLYQAGAFFGALFA 84 Aspergillus nidulans ... P11636 24 CAAIASFAS-CMIGYDSAFIGTTLALPSftkEFDFASYT--PGalal-------------lqsNIVSVYQAGAFFGCLFA 87 Neurospora crassa OR74A P07921 75 LCFITYLCA-TMQGYDGALMGSIYTEDAylkYYHLDINSSsGt-------------------gLVFSIFNVGQICGAFFV 134 Kluyveromyces lactis ...
4JA4_A 76 GYCSNRFGRRDSLKIAAVLFFISGVGSAWPElgftsinpdnTVPVYLAGyvpefviyRIIGGIGVGLASMLSPMYIAELA 155 Escherichia coli K-12 P0C0L7 87 GMLGDKYGRQKILAITIVIMSISTFCIGLIPsydt--igiwAPILLLIC--------KMAQGFSVGGEYTGASIFVAEYS 156 Escherichia coli K-12 P36035 196 GLWTDKSSRKWPYITCLFLFVIAQLCTPWCD-----------TYEKFLGv-------RWITGIAMGGIYGCASATAIEDA 257 Saccharomyces cerevis... P38142 106 GNWANRYGRKYVSMGASAMCMVSSLLLFFSN----------SYLQLLFG--------RFLVGMSCGTAIVITPLFINEIA 167 Saccharomyces cerevis... P22732 90 GPLVNKFGRKGALLFNNIFSIVPAILMGCSRva-------tSFELIIIS--------RLLVGICAGVSSNVVPMYLGELA 154 human P28568 83 SLFFNRFGRRNSMLLVNVLAFAGGALMALSKia-------kAVEMLIIG--------RFIIGLFCGLCTGFVPMYISEVS 147 chicken P38156 169 GPSVDYMGNRYTLIMALFFLAAFIFILYFCK----------SLGMIAVG--------QALCGMPWGCFQCLTVSYASEIC 230 Saccharomyces cerevis... P15325 85 YPIGHFWGRRWGLMFSALIFFLGAGMMLGANgd-------rGLGLIYGG--------RVLAGIGVGAGSNICPIYISEMA 149 Aspergillus nidulans ... P11636 88 YATSYFLGRRKSLIAFSVVFIIGAAIMLAADgq------grGIDPIIAG--------RVLAGIGVGGASNMVPIYISELA 153 Neurospora crassa OR74A P07921 135 P-LMDWKGRKPAILIGCLGVVIGAIISSLTT----------TKSALIGG--------RWFVAFFATIANAAAPTYCAEVA 195 Kluyveromyces lactis ...
4JA4_A 156 PAHIRGKLVSFNQFAIIFGQLLVYCVNYFI-ARSGDaswlntdgWRYMFASECIPALLFLMLLYTVPESPRWL-MSRGKQ 233 Escherichia coli K-12 P0C0L7 157 PDRKRGFMGSWLDFGSIAGFVLGAGVVVLI-STIVGeanfldwgWRIPFFIALPLGIIGLYLRHALEETPAFQ-QHVDKL 234 Escherichia coli K-12 P36035 258 PVKARSFLSGLFFSAYAMGFIFAIIFYRAF-GYFRDd------gWKILFWFSIFLPILLIFWRLLWPETKYFTkVLKARK 330 Saccharomyces cerevis... P38142 168 PVEWRGAMGSMNQVSINLGILLTQTLALKY-ADSYN--------WRWLLFSGSVIAVANILAWLKVDESPRWL-VSHGFV 237 Saccharomyces cerevis... P22732 155 PKNLRGALGVVPQLFITVGILVAQIFGLRN-LLANVd------gWPILLGLTGVPAALQLLLLPFFPESPRYL-LIQKKD 226 human P28568 148 PTSLRGAFGTLNQLGIVVGILVAQIFGLEG-IMGTEa------lWPLLLGFTIVPAVLQCVALLFCPESPRFL-LINKME 219 chicken P38156 231 PLALRYYLTTYSNLCWAFGQLFAAGIMKNSqNKYANse----lgYKLPFALQWIWPLPLAVGIFFAPESPWWL-VKKGRI 305 Saccharomyces cerevis... P15325 150 PPAIRGRLVGVYELGWQIGGVVGFWINYGV-DETLApsh---kqWIIPFAVQLIPAGLLIIGALLIRESPRWL-FLRGNR 224 Aspergillus nidulans ... P11636 154 PPAVRGRLVGIYELGWQIGGLVGFWINYGV-NTTMAptr---sqWLIPFAVQLIPAGLLFLGSFWIPESPRWL-YANGKR 228 Neurospora crassa OR74A P07921 196 PAHLRGKVAGLYNTLWSVGSIVAAFSTYGT-NKNFPnss---kaFKIPLYLQMMFPGLVCIFGWLIPESPRWL-VGVGRE 270 Kluyveromyces lactis ...
4JA4_A 234 E-QAEGILRK---IMGN---TLATQAVQEIKHSLDHGRK----------TGGRLLMFGv----gVIVIGVMLSIFQQFVG 292 Escherichia coli K-12 P0C0L7 235 EqGDREGLQD-----------GPKVSFKEIATKYWRS----------------------------LLTCIGLVIATNVTY 275 Escherichia coli K-12 P36035 331 LiLSDAVKAN----GGE---PLPKANFKQKMVSMKRT------------VQKYWLL---------FAYLVVLLVGPNYLT 382 Saccharomyces cerevis... P38142 238 S-EAETALFK---LRPGt-yQQAKQEIQDWQRSHGHNRDpesse-ethsGPTLWQYVTdpsykkPRTVILAILSCQQFCG 311 Saccharomyces cerevis... P22732 227 EaAAKKALQT---LRGW---DSVDREVAEIRQEDEAEKAagf-----isVLKLFRMRSlr---wQLLSIIVLMGGQQLSG 292 human P28568 220 EeKAQTVLQK---LRGT---QDVSQDISEMKEESAKMSQekk-----atVLELFRSPNyr---qPIIISITLQLSQQLSG 285 chicken P38156 306 D-QARRSLERtlsGKGPekeLLVSMELDKIKTTIEKEQKmsde---gtyWDCVKDGINr----rRTRIACLCWIGQCSCG 377 Saccharomyces cerevis... P15325 225 E-KGIETLAW---IRNL---PADHIYMVEEINMIEQSLEqqrvkiglgfWKPFKAAWTnkrilyRLFLGSMLFLWQNGSG 297 Aspergillus nidulans ... P11636 229 E-EAMKVLCW---IRNL---EPTDRYIVQEVSFIDADLErytrqvgngfWKPFLSLKQrkv-qwRFFLGGMLFFWQNGSG 300 Neurospora crassa OR74A P07921 271 E-EAREFIIKy-hLNGDrthPLLDMEMAEIIESFHGTDLsnpl--emldVRSLFRTRSdr---yRAMLVILMAWFGQFSG 343 Kluyveromyces lactis ...
4JA4_A 293 INVVLYYAPEVFKTLGASTDi-aLLQTIIVGVINLTFTVLA-I--MTVDKFGRKPLQIIGALGMAIGMFSLG-----TAF 363 Escherichia coli K-12 P0C0L7 276 YMLLTYMPSYLSHNLHYSEDhgvLIIIAIMIGMLFVQPVMG----LLSDRFGRRPFVLLGSVALFVLAIPA------FIL 345 Escherichia coli K-12 P36035 383 HASQDLLPTMLRAQLGLSKD----AVTVIVVVTNIGAICGGmIfgQFMEVTGRR-LGLLIACTMGGCFTYP------AFM 451 Saccharomyces cerevis... P38142 312 INSIIFYGVKVIGKILPDYS---IQVNFAISILNVVVTLAA-S--AIIDHVGRRPLLLASTTVMTAMSLLIS-----VGL 380 Saccharomyces cerevis... P22732 293 VNAIYYYADQIYLSAGVPEEh-vQYVTAGTGAVNVVMTFCA-V--FVVELLGRRLLLLLGFSICLIACCVLTa----ALA 364 human P28568 286 INAVFYYSTGIFERAGITQP---VYATIGAGVVNTVFTVVS-L--FLVERAGRRTLHLVGLGGMAVCAAVMTi----ALA 355 chicken P38156 378 -ASLIGYSTYFYEKAGVSTDt-aFTFSIIQYCLGIAATFIS-W--WASKYCGRFDLYAFGLAFQAIMFFIIG-----GLG 447 Saccharomyces cerevis... P15325 298 INAINYYSPRVFKSIGVSGGntsLLTTGIFGVVKAVITFVWlL--YLIDHFGRRNLLLVGAAGGSVCLWIVGgy--iKIA 373 Aspergillus nidulans ... P11636 301 INAINYYSPTVFRSIGITGTdtgFLTTGIFGVVKMVLTIIWlL--WLVDLVGRRRILFIGAAGGSLCMWFIGayikiADP 378 Neurospora crassa OR74A P07921 344 NNVCSYYLPTMLRNVGMKSVslnVLMNGVYSIVTWISSICG-A--FFIDKIGRREGFLGSISGAALALTGLSi---cTAR 417 Kluyveromyces lactis ...
4JA4_A 364 YTQAp---------GIVALLSMLFYVAAFAMSWGPVCWVLLSEIFPNAIRGKALAIAVAAQWLANYFVSWTFPMMDKNSW 434 Escherichia coli K-12 P0C0L7 346 INSN----------VIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTHIRYSALAAAFNISVLVAGLTPTLAAWLVESSQ 415 Escherichia coli K-12 P36035 452 LRSE----------KAILGAGFMLYFCVFG-VWGILP-IHLAELAPADARALVAGLSYQLGNLASAAASTIETQLADRYP 519 Saccharomyces cerevis... P38142 381 TLSV----------SFLLVTATFVYIAAFAIGLGPIPFLIIGELSYPQDAATAQSFGTVCNWLATFIVGYLFPIGHGLMG 450 Saccharomyces cerevis... P22732 365 LQDTvs------wmPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFIQEGLG 438 human P28568 356 LKEKw--------iRYISIVATFGFVALFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGMLFPYAEKLCG 427 chicken P38156 448 CSDThg-------aKMGSGALLMVVAFFYNLGIAPVVFCLVSEIPSSRLRTKTIILARNAYNVIQVVVTVLIMYQLNSEK 520 Saccharomyces cerevis... P15325 374 KPENnpegtqldsgGIAAIFFFYLWTAFYTPSWNGTPWVINSEMFDPTVRSLAQACAAASNWLWNFLISRFTPQMFTSMG 453 Aspergillus nidulans ... P11636 379 GSNKaedak-ltsgGIAAIFFFYLWTAFYTPSWNGTPWVINSEMFDQNTRSLGQASAAANNWFWNFIISRFTPQMFIKME 457 Neurospora crassa OR74A P07921 418 YEKTkkk-----saSNGALVFIYLFGGIFSFAFTPMQSMYSTEVSTNLTRSKAQLLNFVVSGVAQFVNQFATPKAMKNIK 492 Kluyveromyces lactis ...
4JA4_A 435 lvahfhnGFSYWIYGCMGVLAALFMWKFVPETKGKTLEELEALW 478 Escherichia coli K-12 P0C0L7 416 n------LMMPAYYLMVVAVVGLITGVTMKETANRPLKGATPAA 453 Escherichia coli K-12 P36035 520 lerdasgAVIKEDYAKVMAILTGSVFIFTFACVFVGHEKFHRDL 563 Saccharomyces cerevisiae S288C P38142 451 -------GYVFAIFAAIAAMFATYVYKRVPETKGKTT--YSEVW 485 Saccharomyces cerevisiae S288C P22732 439 -------PYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIF 475 human P28568 428 -------PYVFLIFLVFLLIFFIFTYFKVPETKGRTFEDISRGF 464 chicken P38156 521 wn---wgAKSGFFWGGFCLATLAWAVVDLPETAGRTFIEINELF 561 Saccharomyces cerevisiae S288C P15325 454 -------YGVYFFFASLMILSIVFVFFLIPETKGVPLESMETLF 490 Aspergillus nidulans FGSC A4 P11636 458 -------YGVYFFFASLMLLSIVFIYFFLPETKSIPLEAMDRLF 494 Neurospora crassa OR74A P07921 493 -------YWFYVFYVFFDIFEFIVIYFFFVETKGRSLEELEVVF 529 Kluyveromyces lactis NRRL Y-1140
Jiyao W et al.(2023). "The conserved domain database in 2023.",