5YBW,3VSA,1Z7Y,3DWG


Conserved Protein Domain Family
PALP

?
pfam00291: PALP (this model, PSSM-Id:395228 is obsolete and has been replaced by 459749)
Click on image for an interactive view with Cn3D
Pyridoxal-phosphate dependent enzyme
Members of this family are all pyridoxal-phosphate dependent enzymes. This family includes: serine dehydratase EC:4.2.1.13 P20132, threonine dehydratase EC:4.2.1.16, tryptophan synthase beta chain EC:4.2.1.20, threonine synthase EC:4.2.99.2, cysteine synthase EC:4.2.99.8 P11096, cystathionine beta-synthase EC:4.2.1.22, 1-aminocyclopropane-1-carboxylate deaminase EC:4.1.99.4.
Statistics
?
PSSM-Id: 395228
Aligned: 146 rows
Threshold Bit Score: 94.6824
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
?
Program:
Drawing:
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
5YBW_B         18 ISKHILYTPV-----FTSPTFD----RMVGSKagrqFYFKAENLQ-KTGSFXARGAL---NAILCaLEREp-----SLAG 79  Scapharca brou...
jgi:Haur_1568  20 ISLGEGCTPLt---kVKVGRHS--------------FLAKLEFLN-PTGSYKDRGVS---VMMSH-ILSH------QVRQ 71  Herpetosiphon ...
Q5E4U3         63 ITFNEAITPL-----CQA--------EISGTP----ILVKLDSLQ-PTGSFKDRGAS---LVINY-LNNH------GITS 114 Aliivibrio fis...
EAU01274       65 ITLGEGMTAT-----VRFDEK---------------LFFKLDYAM-PTLSFKDRGAA---VLIWL-CKTI------GVKK 113 Campylobacter ...
Q5UZI5         59 VSLGEGWTPL-----VDAPGWD--------------ATFKLESLH-PTGSFKDRGAA---TVIAE-ALEV------GADR 108 Haloarcula mar...
Q5ZUZ9         98 LTFSF---PL-----HHLFKKS----------------YVLELFHgPTLSFKDLGTQffsECLLH-LIEN------KSAK 146 Legionella pne...
Q9ZMX5         74 KRYENFDNPK-----NPAPIFA------LNER----LFVQELYHG-PSLAFKDMALQplaSLFSN-LAVGk----nEKYL 132 Helicobacter p...
jgi:Pput_0696  82 GFRHRGIAPL----------------QQLGHN----EWILQLFHG-PTRSSKDFAAQ----LQAR-FVRHflgaecERVM 135 Pseudomonas pu...
ABR81018       82 VFAHDAVAPL-----RQLNGNE---------------WV-LELFHgPTLAFKDFALQ----LLGR-LLDHvlakrgERVV 135 Pseudomonas ae...
Q8Q0K3         60 lTTEAGPITYksealAKELGLSnlyiGFSG------YWPEREALI-KTCSFKELEAH---PTMQL-LKES------GGKA 122 Methanosarcina...
5YBW_B         80 VVTHSSGNHGQALAWASK--RA-GV-KCCVV--VPKTAPQ--VKFDAMENYGA---EVVKC----EPNPTSRKETCE--- 141 Scapharca brou...
jgi:Haur_1568  72 VIDDSSGNAGASISAYAA--HA-GI-QARIF--VPAHASS--YKKQQIQRFNA---TLVEV----EGLRSATTTA----- 131 Herpetosiphon ...
Q5E4U3        115 IAEDSSGNGGSAYAGYAA--KG-NM-QCNIF--VPAGTSK--GKTTQTRLYGA---NCIEV----EGTREDVALA----- 174 Aliivibrio fis...
EAU01274      114 VLQDSSGNAGNSVAAYCA--RA-GI-ECEIY--VPKGTSQ--KKIDMIRAFGA---TATVF----DGSRDETADACR--- 175 Campylobacter ...
Q5UZI5        109 VLEDSSGNAGLAVASYAA--RA-GL-DAEIY--VPASAKD--AKVRRIERTGA---DVVRV----EGSRESVTEACI--- 170 Haloarcula mar...
Q5ZUZ9        147 VLVATSGDTGAAIAHALD--GKrDL-EGIIL--FPKDKLTf-RQQSQITCWGE---NIRALa--vNGSFDQCQQLVKlvf 215 Legionella pne...
Q9ZMX5        133 VLVSTSGDTGPATLEGLA-----GMpNVFVVclYPKDGT---SLVQKLQMVTQnasNLKVFg--vSGDFDDAQNALK--- 199 Helicobacter p...
jgi:Pput_0696 136 LVGASNGDTAVAAIEALRhcPAaG--LLALY--PSAGTPA--DRAAVMRSAASdsvSCVAV----DGSFDDCQSLVS--- 202 Pseudomonas pu...
ABR81018      136 IMGATSGDTGSAAIEGCR--RCdNV-DIFIM--HPYNRVSevQRRQMTTILGD---NIHNIa--iEGNFDDCQEMVK--- 202 Pseudomonas ae...
Q8Q0K3        123 IVLASAGNTGRAFAYSSS--LT-GT-DAYIV--VPDSGV---SSIWLPEEPAN---SIHLIsmtpGNDYTDAINLAG--- 187 Methanosarcina...
5YBW_B        142 GLAKS---RGYKYISSSd--DYD-----VIAG-QGTIALEL--------LQQQ----PDLD--AILVSVSAG-GMASGIC 195 Scapharca brou...
jgi:Haur_1568 132 CWKEA---QHTTYASHAw--SPF-----FLAG-QMTCAWEMw-------EQLGr---RVPA--AIVCVAGQG-GLLIGLL 187 Herpetosiphon ...
Q5E4U3        175 AIESSv-tHGSHYVGHNw--HPL-----FIEG-VKSIAYEIw-------EQCGy---KAPD--NFVVPAGNG-SLLAGAY 232 Aliivibrio fis...
EAU01274      176 KKALD---EDVYYANHVy--NPM-----FYQG-TKTYVYEIf-------EQLG----RVPE--NFFLPVGNG-TLLIGCE 230 Campylobacter ...
Q5UZI5        171 DAVEDg--AGWYASHAW---NPA-----FFAG-TATAAYEIa-------AQRDw---SVPD--AVVTPLGHG-TLFLGLY 226 Haloarcula mar...
Q5ZUZ9        216 AKREH---KGILTTANSm--NIArllpqIIFYaFTSIQLAL---------RHN----HSVN---FIVPGGNL-GNVTACY 273 Legionella pne...
Q9ZMX5        200 NLLKDddfNEALKARQLk--LSV-----ANSVnFGRIAFQIvyhiwgflELYKkgaiNSKE--KITLAIPSG-NFGNALG 269 Helicobacter p...
jgi:Pput_0696 203 ALLRDw--PCPGLIPVSf--NST-----NWVGvLAQIVFYF----------------------HAALQLGGG-IRPVGFS 250 Pseudomonas pu...
ABR81018      203 ASFAD---QGFLKGTRLvavNSI-----NWARiMAQIVYYFha-----aLQLG----APHRsvAFSVPTGNF-GDIFAGY 264 Pseudomonas ae...
Q8Q0K3        188 RLAKL---PGMVPEGGAr--NVA-----RREG-MGTVMLDAa-------VTIG----KMPD--HYFQAVGSGtGGMSAWE 243 Methanosarcina...
5YBW_B        196 VYTKN-----TKSD--------LKVFLVEPEgkMLEECISKR--ERLWPNPPQFl----------DTIADGIILQq---C 247 Scapharca brou...
jgi:Haur_1568 188 QGFKAllkakLIPHl-------PRLYAVQAR--ACDPIVRAWeeRKEFPQACVEq----------TTLAEGIRIAqp-vR 247 Herpetosiphon ...
Q5E4U3        233 IGFSEl---lKGGEis----klPRLFGIQSE--SIQPFVQTF---NNKEINITSe----------DTIAEGIKIKrs-sR 289 Aliivibrio fis...
EAU01274      231 LALSEll-raGAIAk------aPKIFIVQSE--NCAPLFGAT----NKPRDIVPk----------PTQAEGIAIGk---P 284 Campylobacter ...
Q5UZI5        227 RGFQAle-qaGWTDa------iPRILGTQAV--GYSPIADDD--EGGTVPDDAAa----------NDLADGIHIRdp-pR 284 Haloarcula mar...
Q5ZUZ9        274 WAKML-----GFPV--------EQILIANNI---NSALGEFL--LTGAYQAKSVt----------KTLATAMDVGep-sN 324 Legionella pne...
Q9ZMX5        270 AFYAK-----KMGL---------NIAKIKVVtnSNDVLREFI--ETGRY----------------DLTKRSLKQTf--sP 315 Helicobacter p...
jgi:Pput_0696 251 IPTASfa-eiYAGFiaqkmglpINQIIVSTN--RNDALHRFI--HCNRYSRGSTs----------QTLSPVMDFSlfsnL 315 Pseudomonas pu...
ABR81018      265 LARNM-----GLPV---------SQLIVATN--RNDILHRFM--SGNRYDKDTLh----------PSLSPSMDIMvssnF 316 Pseudomonas ae...
Q8Q0K3        244 ASLRLrd-dgRFGSk------lPKLQLAQNL--PFVPMYNAW--KAGRREIIPDidmkdakkqieETYATVLTNRa--pP 310 Methanosarcina...
5YBW_B        248 GNKTWPII---LELPEk----EVITVNNDNIVEAMRFVFARMKLVIEAAAGATVAAAmtERFQNFHPEAKKVGIILCG 318 Scapharca brough...
jgi:Haur_1568 248 GRDILRAI---YESAG-----AAIRVEEHEILAAQAMLA-HQGLLVEATSAAAVAGLsqICQLTELAPD-DIVIPLTG 315 Herpetosiphon au...
Q5E4U3        290 MNEIVQFV---KETNG-----NFISVNEQQIQSALKEMG-AQGYFIEPTSATAFAGIaqLIKTQEIKPDELTVGVVTG 358 Aliivibrio fisch...
EAU01274      285 MRGEQILA---GSYEGe---rEVITIPEADIVPTRQRLA-RGGFYVEHTTAAIYAAYlnYIKTHELKGE--SIISLCG 353 Campylobacter cu...
Q5UZI5        285 GRQIRHAI---DETDG-----AAVAVSAAATERERDRLG-AAGFHVEPTCATATAALpeFRERGELQDGDDVVVALTG 353 Haloarcula maris...
Q5ZUZ9        325 LDRLFVLF---NNYSEckkqmNAESVSDEQIKQAILHCYNKYHYIICPHTATAYHRL------STINQDKPWVIVAPG 393 Legionella pneum...
Q9ZMX5        316 AMDILKSS---NVERA-----LFSLFGFERTLELMQALEEEKFYALKP---KELALLqeHFSCASCSDE-DCLKTIQE 381 Helicobacter pyl...
jgi:Pput_0696 316 ERFVWELY---DRDGG-------ATRALMEHFEACGELSIGNRQWL--HARMLFDSY--AVDDALIREE-----IVTl 374 Pseudomonas puti...
ABR81018      317 ERLLFDLH---GRNGK-------AVAELLDAFKASGRLSVEDERWTEAr---------kLFDSLAVSDE-QTCETIAE 374 Pseudomonas aeru...
Q8Q0K3        311 YSITGGLYdalVDTDG-----IMYAITREEALEAKALFESLEGIDILEPSAVAAASLlkAVEAGNVEKDDVILLNIAG 383 Methanosarcina m...
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap