4QQL,4OUS,2JG8,1PK6


Conserved Protein Domain Family
C1q

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pfam00386: C1q 
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C1q domain
C1q is a subunit of the C1 enzyme complex that activates the serum complement system.
Statistics
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PSSM-Id: 395310
View PSSM: pfam00386
Aligned: 32 rows
Threshold Bit Score: 101.978
Threshold Setting Gi: 74824148
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4QQL_I        10 AFYAGLKRQHEGYe--------VLKFDDVVTNLGNHYDPTTGKFTCSIPGIYFFTYHVLmrGGDGTSMWADLCKNNQVRA 81   house mouse
XP_021323416  61 AFSASLLSSHNIKyigpyaedtMIVYGKIFTNIGNAYNTTTGIFSAPVKGVYFFNLVLF--THDALSAGVKLLKNDDHVV 138  zebrafish
NP_001338766 772 AFFASVNSILPATa-------kVVVFGQVLYNGQNHYNQTSGMFLCQIPGVYEFEFSCI---GTRSLGFVTLKKNNRVEL 841  zebrafish
4OUS_A         7 AFSAARTANFAPGtl-----dqPIAFDLLHTNLGDMFDTGSGRFTCPATGAYVFIFHILk-LAISVPLYINLMRNEEVMV 80   zebrafish
Q9ES30       119 AFMASLATHFSNQn-------sGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFFTFSMMk-HEDVEEVYVYLMHNGNTVF 190  house mouse
A6H6E2       821 AFYAGSSEGATALq--------MVKFNTTSINVGSSYFPEHGYFRAPKRGVYLFAVSIT--FGPGPGMG-QLVFEGHHRV 889  house mouse
Q9QXP7       147 AFSVGRKKALHSNdy-----fqPVVFDTEFVNLYKHFNMFTGKFYCYVPGIYFFSLNVH--TWNQKETYLHIMKNEEEVV 219  house mouse
Q9BXI9       145 AFSVGRKTALHSGed-----fqTLLFERVFVNLDGCFDMATGQFAAPLRGIYFFSLNVH--SWNYKETYVHIMHNQKEAV 217  human
P60827       118 AFSVGRREGLHSSdh-----fqAVPFDTELVNLDGAFDLAAGRFLCTVPGVYFLSLNVH--TWNYKETYLHIMLNRRPAA 190  human
Q8R066        30 AFSAARTTPLEGTse------mAVTFDKVYVNIGGDFDAATGRFRCRVPGAYFFSFTAG--KAPHKSLSVMLVRNRDEVQ 101  house mouse
4QQL_I        82 SAIAQDADQN--YDYASNSVVLHLEPGDEVYIKLDg----GKAHGGNNnKYSTFSGFII 134  house mouse
XP_021323416 139 GVTDNPPTEDk-EDTASNSVSLLLEEGDQISVKLIa---hRRIYTDGF-RRNTFSGHLL 192  zebrafish
NP_001338766 842 TPETVALNTR---SLAEGKAVLSLQRGDRVYVEVSr-------sANGIgFSSYFSGHIL 890  zebrafish
4OUS_A        81 SAYANDGAPD--HETASNHAVLQLFQGDQVWLRLH-----RGAIYGSSwKYSTFSGFLL 132  zebrafish
Q9ES30       191 SMYSYETKGK--SDTSSNHAVLKLAKGDEVWLRMG-----NGALHGDHqRFSTFAGFLL 242  house mouse
A6H6E2       890 PVYSTEQRGG---STATTFAMVELQKGERAWFELI-----QGSATKGSqPGTAFGGFLM 940  house mouse
Q9QXP7       220 ILYAQVSDRS---IMQSQSLMMELREEDEVWVRLFkgereNAIFSDEFdTYITFSGYLV 275  house mouse
Q9BXI9       218 ILYAQPSERS---IMQSQSVMLDLAYGDRVWVRLFkrqreNAIYSNDFdTYITFSGHLI 273  human
P60827       191 VLYAQPSERS---VMQAQSLMLLLAAGDAVWVRMFqrdrdNAIYGEHGdLYITFSGHLV 246  human
Q8R066       102 ALAFDEQRRPgaRRAASQSAMLQLDYGDTVWLRLH-----GAPQYALGaPGATFSGYLV 155  house mouse
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