2COZ,2CP6,1WHG,1WHH,2CP5,2HKN,1WHK,4B6M,1IXD


Conserved Protein Domain Family
CAP_GLY
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pfam01302: CAP_GLY (this model, PSSM-Id:396049 is obsolete and has been replaced by 460154)
CAP-Gly domain
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.
Links
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Statistics
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PSSM-Id: 396049
Aligned: 612 rows
Threshold Bit Score: 40.4759
Created: 22-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2COZ_A                          34 IGDR--V------L-IGNVQP---GILRFKG-E-TSFAKG----F-WAGVELDK--PEGNNNGTYDGIAYFECKEKHGIF 92   human...
WGS:AAGF:cds.TTHERM_00823400A    8 VNDR--I------KlTNNANKdqeGTILYIG-Q-LDGKEG----I-WIGVELDL--PKGSHNGQFNGKQYFQGRDQHCMF 70   Tetrahymena thermophila SB210...
EGR33564                         8 VGDY--V------QlTNTQNKdqeGYIKFIG-Q-LEGKEG----I-WVGVELTI--QKGTHNGTFQDKKYFECKELHGIF 70   Ichthyophthirius multifiliis...
XP_002117948                    19 DGSI--V------N----------GIIKYTG-P-LVSMIG----E-WIGVQLDR--PIGRHNGLFKGRQYFTCPHRYGVF 71   Trichoplax adhaerens...
XP_001624773                     9 VGAR--Ve----vLwRGEVCK---GAVRYTG-M-LVAKPG----E-WIGIELDD--RVGSHSGLHKGVQYFKCKDGHGIF 70   starlet sea anemone...
EEN49292                         9 VGQR--Ve----vLyHGTIEH---GTVRYTG-H-LNGMRG----N-WVGVEFDF--QVGKHNGTFLGRHYFSCKDGHGVF 70   Florida lancelet...
A0CKR3                           6 EGDY--VtilkdpIk---nEK---GYIRYLG-E-LEGRPG----T-FYGIHLDN--KVGSHNGTLQGKEYFTCPEGHGLF 68   Paramecium tetraurelia...
XP_002649397                    14 KGDS--V------S-INNKYF---GKIQYIG-P-IENKDG----I-WVGIELNK--PVGKNNGTYMGIKYFDCRPNYGIF 72   Enterocytozoon bieneusi H348...
Q4UGG2                           6 VNDQvmV------Yg----FR---GVVKYIGkKeYIkkpTgnvvNqLVGVELVKklPq-CTNGNLNGTNVFDTKAETALF 71   Theileria annulata...
XP_009022371                   222 LGDR--Iiw---yNdNDDGEF---GNVRWIG-E-LPDHNG----S-FAGVEFDN--PIGSATGIYKNVKYFTARPKHALF 284  Helobdella robusta...

2COZ_A                          93 APPQKI 98   human
WGS:AAGF:cds.TTHERM_00823400A   71 VKEKHI 76   Tetrahymena thermophila SB210
EGR33564                        71 VREKHL 76   Ichthyophthirius multifiliis
XP_002117948                    72 TRPENI 77   Trichoplax adhaerens
XP_001624773                    71 TRARNI 76   starlet sea anemone
EEN49292                        71 LHASRL 76   Florida lancelet
A0CKR3                          69 ITGNHL 74   Paramecium tetraurelia
XP_002649397                    73 VKENKI 78   Enterocytozoon bieneusi H348
Q4UGG2                          72 IPLETL 77   Theileria annulata
XP_009022371                   285 LPMAGL 290  Helobdella robusta
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