2MAH


Conserved Protein Domain Family
Fz
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pfam01392: Fz (this model, PSSM-Id:396115 is obsolete and has been replaced by 460190)
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Fz domain
Also known as the CRD (cysteine rich domain), the C6 box in MuSK receptor. This domain of unknown function has been independently identified by several groups. The domain contains 10 conserved cysteines.
Links
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Statistics
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PSSM-Id: 396115
Aligned: 286 rows
Threshold Bit Score: 44.0205
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2MAH_A        16 CYPTsnatnT---CFGsk----lpY-ELS-Sldl-tdfHTEKelndkLNDY---YALKHVp-----KCWAAIQPFLCAVF 77   fruit fly
XP_028910705 258 CSTYk----Ge-vCSAvlvkdalvFfNSSyA-------DSEK-----IQEMlaqAVWSELktv-slLCRQAAESLLCNHV 319  platypus
XP_007498661 337 CSTYr----Ge-vCGAvlakdalvFyNSSyQ-------DSGD-----AQELlvqTIWSDLkal-spLCQPAMESLLCNHI 398  gray short-tai...
XP_006088096 317 CAQYr----Ge-vCNTvlangalvFfNNSyA-------DPEE-----AQELlvhTAWSELrav-spFCRPAAEALLCNHI 378  little brown bat
Q497X0       327 CAQYr----Ge-vCDAvlakdalvFfNTSyR-------DPED-----AQELlihTAWNELkav-spLCRPAAEALLCNHL 388  house mouse
XP_022536964 323 csTY-----RgevCDGal-----rQ-NAL-VffnfslpDPENaq--eLLAR---ASWSELdwa-spLCRPAARSLLCHNA 384  Mexican tetra
G5EGK5       205 CVQY-----RgeaCRQy------lS-NKF-VmmtnesrEEMYdidrnLRAA---MLFINGaptisqKCRQLSQAVACHHM 268  Caenorhabditis...
XP_020930106 317 CAQY-----RrevCKAvl-----aR-DAL-VffnnsyaDPEEaq--eLLVH---TAWNELkav-spFCRPAAEALLCNHI 378  pig
XP_010199214 248 CSTY-----RgevCSAil-----aK-NAL-VffnssyaDPEEtqellVHTAwteLKMVSS------FCQPAAESLLCNYI 309  speckled mouse...
XP_012808865 316 CSTYr----Gd-vCSSvlakdslvFfNSSnA-------EPEE-----SQEMlaqTTWNELktv-ssFCRPAAEAFLCNYF 377  tropical clawe...

2MAH_A        78 KPKCekinGEdmVYLPSYEMCRI-TMEPCRILYntTFfpk---------------flRCNetLFP 126  fruit fly
XP_028910705 320 FQEChptaVIptPKPICREHCLAvRDQYCSNDWltMEakshkglyq--sglhqlilpECS--KLP 380  platypus
XP_007498661 399 FQGCnparFMptPKPLCREHCLAvKDLFCAKEWlaLEekahkglyk--sglhlftlpECT--KLP 459  gray short-tailed opossum
XP_006088096 379 FQECnp-gVLptPIPICREYCLGvKELFCAKEWlaLEekthrglyr--pglhllsvlDCS--KLP 438  little brown bat
Q497X0       389 FQECsp-gVVptPMPICREYCLAvKELFCAKEWqaMEgkahrglyr--sgmhllpvpECS--KLP 448  house mouse
XP_022536964 385 FQDCspsgLGpsPKPLCREHCVAvKELYCYKEW--RAseershrgvm-spglsialtDCR--KLP 444  Mexican tetra
G5EGK5       269 YKVCes-dSNnqIVSICKHDCDViQNDECPSELa-LAaqhel-----------vgdtPKA--LFP 318  Caenorhabditis elegans
XP_020930106 379 FQEChp-gVVptPIPICREYCLAvKELFCAKEW--LAleekthrglyrsemhllsvpECN--KLP 438  pig
XP_010199214 310 FQECnpsgAGpaPKPLCRENCLAvKDLYCFKEW--LSmeensqkgiykpglmlltlpECN--RLP 370  speckled mousebird
XP_012808865 378 FQECnptgEGptPKPMCREHCLAvKDLYCFKDWlsMEensrkgiyk--hglmllalpDCD--KLP 438  tropical clawed frog
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