pfam01728: FtsJ (this model, PSSM-Id:396336 is obsolete and has been replaced by 426399)
FtsJ-like methyltransferase
This family consists of FtsJ from various bacterial and archaeal sources FtsJ is a methyltransferase, but actually has no effect on cell division. FtsJ's substrate is the 23S rRNA. The 1.5 A crystal structure of FtsJ in complex with its cofactor S-adenosylmethionine revealed that FtsJ has a methyltransferase fold. This family also includes the N-terminus of flaviviral NS5 protein. It has been hypothesized that the N-terminal domain of NS5 is a methyltransferase involved in viral RNA capping.
Jiyao W et al.(2023). "The conserved domain database in 2023.",