6H6P,4JGX,3CNU


Conserved Protein Domain Family
SCP2
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pfam02036: SCP2 (this model, PSSM-Id:396566 is obsolete and has been replaced by 460423)
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SCP-2 sterol transfer family
This domain is involved in binding sterols. It is found in the SCP2 protein, as well as the C-terminus of the enzyme estradiol 17 beta-dehydrogenase EC:1.1.1.62. The UNC-24 protein contains an SPFH domain pfam01145.
Links
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Statistics
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PSSM-Id: 396566
Aligned: 113 rows
Threshold Bit Score: 51.0835
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6H6P_D             26 LNTFLYRs------pALKTARSRLLGk------VLRVEVKGFST---SLILVFS---ER-QVDVl----gEWA-GDADCT 81  Escherichi...
WP_012116416        4 LSSLVEAm------rERSDALSELGY-------KVRFDLTDTGE---AILLDAT---GG-AVEVgeg------sgEADAV 57  Xanthobact...
WP_011777807       12 araYRDLwnd---saEIRQGAKELSM-------LIEWRVQDANDq--VSQLEIT---DG-EAIYgg---vQIQgRKPDFV 72  Mycoliciba...
jgi:HY04AAS1_0102  10 IKAYKDQwnk---neKLKNDLKNFSA-------KLKYYIISKENe--AVELIIK---NGeAISCg----mADG-KDYDFE 69  Hydrogenob...
O66500             15 IKAYAEEwnk---neKLMNDLKNFSA-------SIKYYVEGKEN----DAVELI---IE-KGKAvsa-gkADPnKRYDFE 75  Aquifex ae...
WP_012513600       42 LVGMASSss-----eWRGAPVRKLFL--------YRKDCSPRKQi--ELYIQNM---NG-KAECiyggwaKDGrTGNDFL 102 Hydrogenob...
O66445             26 AKQFCEVwnntpelvEKLGKSESWTEvperklfLYRKDCGPEKQ----IQLTIKnenGR-AVCVygg-wkKDEkTDNDFL 99  Aquifex ae...
Q1AT92             16 FERMREEl--------dADQIRELRG-------TYEFDIKDAg----KFIVRFNe--DG-TLEVfde-gsGV---EPDCT 69  Rubrobacte...
EDO32231          266 VTLVQGVl--------eEDMTSRIGG-------TYLFDITGENGg--TWIMDLSt-vPG-SIRAtdk-lvE----SPDVT 321 starlet se...
Q8CI66            296 LTALQPFl--------sEALVSQVGA-------CYQFNVILPSGtqsIYFLDLT---TG-QGRVghg-epDG---IPDVV 352 house mouse

6H6P_D             82 VIAYASVLPKLRDRQ-QLTALIRSGELEVQGDIQVVQNFVALA 123 Escherichia coli K-12
WP_012116416       58 LKLSTDTLDKLITGRmGPLMAFSTGRLKVQGSQGVALKLAGLL 100 Xanthobacter autotrophicus
WP_011777807       73 LTATASVWHRVADGElGVANAIATRKIKFVGPVKVAMANMAVL 115 Mycolicibacterium vanbaalenii
jgi:HY04AAS1_0102  70 MWATLEDWKSLATGQmGPKAAMLTKKLKFKGSMITAMKYMGAF 112 Hydrogenobaculum sp. Y04AAS1
O66500             76 LWASLENWKKLATGEmGPRAAMLTKRLKFKGSMITAMKYMGAF 118 Aquifex aeolicus
WP_012513600      103 MYATTKHWIEMGRGEyGPMHAMMFGELSFSGPKFVAMANMGPF 145 Hydrogenobaculum sp. Y04AAS1
O66445            100 MYADTKRWLEMGRKEyGPMKAMLFGRLKFEGPRFVAMKNMGPF 142 Aquifex aeolicus
Q1AT92             70 LMAKEKDWLSIVSGRtKPMSAFMTNKLKVKGSLGKAMKLQKVL 112 Rubrobacter xylanophilus DSM 9941
EDO32231          322 FSMSVDEMVNIFYGQvTPFNSYMQGGLKVDGDLKMAMNLETII 364 starlet sea anemone
Q8CI66            353 VEMAEADLQALLSKElRPLGAYMSGRLKVKGDLAVVMKLEAVL 395 house mouse
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