6P2R


Conserved Protein Domain Family
MIR

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pfam02815: MIR 
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MIR domain
The MIR (protein mannosyltransferase, IP3R and RyR) domain is a domain that may have a ligand transferase function.
Statistics
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PSSM-Id: 397103
Aligned: 30 rows
Threshold Bit Score: 144.429
Threshold Setting Gi: 74786742
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6P2R_A  343 GYL---------HSHSHNYP----AGSEQQQ-----------STLYPHMDANND----------WLLELYNAPgesLTTF 388  Saccharomyces cerev...
P91905  220 GFLfgndvlrlfHGN-DECL----TIPENWSehp-----qhnMVIYEGGAAVTQar------slWRVELIRM----KWHG 279  Caenorhabditis elegans
Q24498  211 GYVfggdvlrffHGG-DECL----TIPSTWGrea-----gqnIVIYEGGVVMAQar------slWRLELART----KWTG 270  fruit fly
Q6BFC5  240 GFLsiqdtvwinYSEQDVILlilfTIAQPHChqrlnqkselhIFFEQCTQSANYtkfvgnsnglFTIESESM-----FQG 314  Paramecium tetraurelia
Q9Y0A1  320 NSVksgdvvrlfHADQQTFL----TLDTIPKqnpptdvvflrMTNRPSAADATSsr------alWEVQVVQTN---AYRG 386  Caenorhabditis elegans
P29993  239 HILkggdvvrlfHAEQEKFL----TMDEYKKqyhv----flrTTGRTSATAATSsk------alWEIEVVQHD---SCRG 301  fruit fly
O77089  234 GVLkggdvirlfHAEQEKFL----TMDEYKKkqhv----flrTTGRTTATAATSsk------alWEVEVVQHD---PSRG 296  Caribbean spiny lob...
Q8WSR4  231 DGLkggdvvrlfHAEQEKFL----TCDEYKKksyi----flrTTGRVSATAATSsk------alWETEVVQHD---PCRG 293  Patiria pectinifera
Q14643  232 DILkggdvvrlfHAEQEKFL----TCDEHRKkqhv----flrTTGRQSATSATSsk------alWEVEVVQHD---PCRG 294  human
Q6W3E4  232 DVLkggdvvrlfHAEQEKFL----TCDDYEKkqhi----flrTTLRQSATSATSsk------alWEIEVVHHD---PCRG 294  Norway rat
6P2R_A  389 QNLTDGTK-----VRLFHTVTRCRLHSHDH------------------------------KPPVSESsDWQKEVSCYGYS 433  Saccharomyces cerev...
P91905  280 ALVGWEQV-----FRIKHITSGRYLGVLDN------------------------------SVQLYHKeKADFDLTAFVMC 324  Caenorhabditis elegans
Q24498  271 GFINWYHP-----MRIRHITTGRYLGVNDSn-----------------------------ELILVKKeEASIATTTFCLR 316  fruit fly
Q6BFC5  315 GLVKWDTPmisssYRLRHLTTKKYLKVVEEkket-----------------------edkSRFLLTSvSDYQKASLFHF- 370  Paramecium tetraurelia
Q9Y0A1  387 GTAKWNKA-----YRFKHLATDMYLSAEPSqvqvkpamng----------rrasliysktNNPMAMYsDGPNGVTNESTD 451  Caenorhabditis elegans
P29993  302 GAGDWNSL-----YRFKHLATGHYLAAEAEidvsagamsatsasghdlhlgdcskdsglsCSTMNSTiNDKPKGKQYRLV 376  fruit fly
O77089  297 GAGHWNSL-----FRFKHLATGHYLAAEIDdd--------------------------ptPDPTRTKlRDPNGGPVYQLV 345  Caribbean spiny lob...
Q8WSR4  294 GAGHWNSL-----FRFKHLATGQYMAAEVDnd--------------------------ntKDHTREKlRGPHGGTVYQMV 342  Patiria pectinifera
Q14643  295 GAGYWNSL-----FRFKHLATGHYLAAEVDpdfeeecle-------------fqpsvdpdQDASRSRlRNAQEKMVYSLV 356  human
Q6W3E4  295 GAGQWNSL-----FRFKHLATGNYLAAELNpdyrdaqn--------------egktvrdgELPTSKKkRQAGEKIMYTLV 355  Norway rat
6P2R_A  434 GFDGDa-------------NDDwvVEIDKKNSAPGVAQERVI-ALDTKFRLRHAMTGC--YLFSHEVKLPAW-----GFE 492  Saccharomyces cerev...
P91905  325 QN-----------------KDPk-KQMLDEKEEEGMGNATIR-YGETNAFIQHVKTQL--WLSYQTTEVTKK-----GLG 378  Caenorhabditis elegans
Q24498  317 QEK----------------DDE--KKVLEDKDLEVIGSPIIK-YGDTTVIVQHCETSL--WLSYKSYETKKK-----GVG 370  fruit fly
Q6BFC5  371 ------------------------ELIFSTLTTYNREKAQLYlQKDSYFRASTYVGQDqvWLRTESIQNEEEn----KDI 422  Paramecium tetraurelia
Q9Y0A1  452 TTQQNipsvwvlgptksefPEEdaNLLFQLDPSTFMKSNKEV-PRRSYVRLLHQSSDK--WVHATNATEKQNlhyssKNE 528  Caenorhabditis elegans
P29993  377 SVPYS--------------ADI--ASVFVLDATTMARPDSLV-PQSSYVRLQHICSNT--WVHATSIPIDAD-----DDK 432  fruit fly
O77089  346 SVPLS--------------NDI--ASIFELEPTTLIRGDSMV-PQSSYVRLRHLCTST--WVHSTSIPIDKE-----EDK 401  Caribbean spiny lob...
Q8WSR4  343 PIIHG--------------NDI--ASIFELDPTTLQGGDSMV-PRSSYVRLRHLCTNT--WVHSTSIPLDKG-----EDK 398  Patiria pectinifera
Q14643  357 SVPEG--------------NDI--SSIFELDPTTLRGGDSLV-PRNSYVRLRHLCTNT--WVHSTNIPIDKE-----EEK 412  human
Q6W3E4  356 SVPHG--------------NDI--ASLFELDATTLQRADCLV-PRNSYVRLRHLCTNT--WVTSTSIPIDTE-----EER 411  Norway rat
6P2R_A  493 ---QQEVTCASSGRHD--LTlwyvennsnplLP 520  Saccharomyces cerevisiae W303
P91905  379 kveEKKAVALKDGHMDdcYT-----------FF 400  Caenorhabditis elegans
Q24498  371 kveEKQAILHEEGKMDdcLD-----------FS 392  fruit fly
Q6BFC5  423 skeKKKSVPAFNKVKKeeYV-----------FK 444  Paramecium tetraurelia
Q9Y0A1  529 k-gWVKVICEKNRVDKetFA-----------LL 549  Caenorhabditis elegans
P29993  433 p-vMSMVCCSPIKEDKeaFA-----------LI 453  fruit fly
O77089  402 p-vMSKVGCAPIKEDKeaFS-----------LV 422  Caribbean spiny lobster
Q8WSR4  399 p-vMLKVGTAQIREDReaFA-----------II 419  Patiria pectinifera
Q14643  413 p-vMLKIGTSPVKEDKeaFA-----------IV 433  human
Q6W3E4  412 p-vMLKIGTCQTKEDKeaFA-----------IV 432  Norway rat
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