Conserved Protein Domain Family
SARA
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pfam11409: SARA (this model, PSSM-Id:402839 is obsolete and has been replaced by 463271)
Smad anchor for receptor activation (SARA)
Smad proteins mediate transforming growth factor-beta (TGF-beta) signaling from the transmembrane serine-threonine receptor kinases to the nucleus. SARA recruits Smad2 to the TGF-beta receptors for phosphorylation.
Links
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Statistics
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PSSM-Id: 402839
Aligned: 8 rows
Threshold Bit Score: 35.9911
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_005155592  712 SPNPNIPSEYCSTIPPMQQARAAgtLNSPPPTVMVPVSV 750  zebrafish
XP_002428675  132 RPNPNNPMEYCSTVPPPLQINSS--GSQPPPSVMVPVGV 168  human body louse
XP_002606889 1173 SPNPNNPMEYCSTLPPMQQAQEA--LQRPPPSVLVPVGg 1209 Florida lancelet
XP_008180257  485 HPNPNNPMEYCSTVPPLQQVTDS--KNQPVPSVLVPVSV 521  pea aphid
Q7QH71        152 QPNPNNPMEYCSVIPPLQQAAASnqPQSPI-SVMVPVGV 189  Anopheles gambiae str. PEST
1_pfamImport    1 SPNPNNPMEYCSTLSPYQQVEIEnnAKTQM-EVMVPVSV 38  
Q16WS9        708 QPNPNNPMEYCSTVPPFQQATNQ--PQSPI-SVMVPVGV 743  yellow fever mosquito
XP_014282114  629 QPNPNNPMEYCSTIPPLQQAASS--MNQPPPSVLVPTGV 665  brown marmorated stink bug
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